Anti-P2X6 Receptor (extracellular) Antibody | Alomone Labs APR-028 product information

product summary

company name :

Alomone Labs

product type :

antibody

product name :

Anti-P2X6 Receptor (extracellular) Antibody

catalog :

APR-028

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

reactivity :

mouse, rat

application :

western blot

more info or order :

Alomone Labs product webpage

citations: 3

Reference
Xu X, Li Y, Wu Y, Xu Y, Weng R, Wang C, et al. Upregulation of spinal ASIC1 by miR-485 mediates enterodynia in adult offspring rats with prenatal maternal stress. CNS Neurosci Ther. 2021;27:244-255 pubmed publisher
Patel J, Bourne L, Millan J, Arnett T, Macrae V, Wheeler Jones C, et al. Inhibition of vascular smooth muscle cell calcification by ATP analogues. Purinergic Signal. 2019;15:315-326 pubmed publisher
Fagerberg S, Patel P, Andersen L, Lui X, Donnino M, Praetorius H. Erythrocyte P2X1 receptor expression is correlated with change in haematocrit in patients admitted to the ICU with blood pathogen-positive sepsis. Crit Care. 2018;22:181 pubmed publisher

image

image 1 :

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: - 1,2. Anti-P2X6 Receptor (extracellular) Antibody (#APR-028), (1:200).3,4. Anti-P2X6 Receptor (extracellular) Antibody, preincubated with P2X6 Receptor (extracellular) Blocking Peptide (#BLP-PR028).

product information

CAT :

APR-028

SKU :

APR-028-CF_0.2 ml

Product Name :

Anti-P2X6 Receptor (extracellular) Antibody

Group Type :

Antibodies

Product Type :

Antibodies

Clonality :

Polyclonal

Accession :

P51579

Applications :

Reactivity :

Rat Mouse

Host :

Rabbit

Blocking Peptide :

BLP-PR028

Homology :

Mouse - 13/14 amino acid residues identical; human - 11/14 amino acid residues identical

Formulation :

PBS pH7.4

isotype :

Rabbit IgG

Peptide confirmation :

Confirmed by amino acid analysis and mass spectrometry

Reconstitution :

0.2 ml double distilled water (DDW).

Antibody Concentration After Reconstitut ... :

1 mg/ml

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Preservative :

No Preservative

Immunogen Location :

Extracellular

Label :

Unconjugated

Storage Before Reconstitution :

The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

immunogen source species :

Rat

Sequence :

CPEGEMGTYSHGIK, corresponding to amino acid residues 136-149 of rat P2X6 receptor

Product Page - Scientific background :

P2X receptors belong to the ligand-gated ion channel family and are activated by extracellular ATP. P2X receptors are involved in synaptic communication and in diseases of the nervous system. The P2X receptor family consists of at least seven isoforms: P2X1-P2X7.1,2,3 All P2X subunits can assemble to form homomeric or heteromeric functional channels with the exception of P2X6, which only seems to function as part of a heteromeric complex.4-9 The P2X6 receptor assembles to a heteromultimer with two other P2X subunits, P2X2 and P2X4. P2RX6 is extensively expressed throughout the central nervous system.7

Applications may also work in :

Supplier :

Alomone Labs

Target :

P2RX6, P2X purinoceptor 6, P2XM, Purinergic receptor P2X-like 1, P2RXL1

Short Description :

A Rabbit Polyclonal Antibody to P2X6 Receptor

Long Description :

Alomone Labs is pleased to offer a highly specific antibody directed against an epitope of the rat P2X6 purinergic receptor. Anti-P2X6 Receptor Antibody (#APR-028) can be used in western blot applications. The antibody recognizes an extracellular epitope and is thus ideal for detecting P2RX6 in living cells. It has been designed to recognize P2RX6 from rat, mouse and human samples.

Negative Control :

BLP-PR028

Positive Control :

Synonyms :

P2RX6, P2X purinoceptor 6, P2XM, Purinergic receptor P2X-like 1, P2RXL1

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot

Specifictiy :

P2RX6

Form :

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.

Comment :

Contact Alomone Labs for technical support and product customization

Species reactivity key :

H- Human, M- Mouse, R- Rat

Is Toxin :

Purity :

Affinity purified on immobilized antigen.

UNSPSC :

41116161

Clone :

Standard quality control of each lot :

Western blot analysis

Antigen preadsorption control :

1 µg peptide per 1 µg antibody

Application Dilutions: Immunohistochemis ... :

Contact Alomone for information

Application Dilutions: Western blot wb :

1:200

more info or order :

Alomone Labs product webpage