Anti-P2X6 Receptor Antibody | Alomone Labs APR-013 product information

product summary

company name :

Alomone Labs

product type :

antibody

product name :

Anti-P2X6 Receptor Antibody

catalog :

APR-013

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Alomone Labs product webpage

citations: 2

Reference
Centeio R, Ousingsawat J, Schreiber R, Kunzelmann K. CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A. Int J Mol Sci. 2021;22: pubmed publisher
Doyle C, Cristofaro V, Sack B, Mahmood F, Sullivan M, Adam R. The role of the mucosa in modulation of evoked responses in the spinal cord injured rat bladder. Neurourol Urodyn. 2018;37:1583-1593 pubmed publisher

image

image 1 :

Western blot analysis of rat brain membranes: - 1. Anti-P2X6 Receptor Antibody (#APR-013), (1:200). 2. Anti-P2X6 Receptor Antibody, preincubated with P2X6 Receptor Blocking Peptide (#BLP-PR013).

image 2 :

Expression of P2X6 in rat hypothalamus. - Immunohistochemical staining of perfusion-fixed frozen rat brain sections Anti-P2X6 Receptor Antibody (#APR-013), (1:200), followed by goat anti-rabbit-AlexaFluor-488. A. P2X6 immunoreactivity (green) appears in neurons (arrows). B. Pre-incubation of the antibody with P2X6 Blocking Peptide (BLP-PR013), suppressed staining. Cell nuclei are stained with DAPI (blue). 3rd V = Third ventricle.

product information

CAT :

APR-013

SKU :

APR-013-CF_0.2 ml

Product Name :

Anti-P2X6 Receptor Antibody

Group Type :

Antibodies

Product Type :

Antibodies

Clonality :

Polyclonal

Accession :

P51579

Applications :

IC IF IFC IHC WB

Reactivity :

Human Rat Mouse

Host :

Rabbit

Blocking Peptide :

BLP-PR013

Homology :

Mouse - 15/17 amino acid residues identical; human - 14/17 amino acid residues identical

Formulation :

PBS pH7.4

isotype :

Rabbit IgG

Peptide confirmation :

Confirmed by amino acid analysis and mass spectrometry

Reconstitution :

0.2 ml double distilled water (DDW).

Antibody Concentration After Reconstitut ... :

1 mg/ml

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Preservative :

No Preservative

Immunogen Location :

Intracellular, C-terminus

Label :

Unconjugated

Storage Before Reconstitution :

The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

immunogen source species :

Rat

Sequence :

(C)RTKYEEARAPKATTNSA, corresponding to amino acid residues 363-379 of rat P2X6 receptor

Product Page - Scientific background :

P2X receptors belong to the ligand-gated ion channel family and are activated by extracellular ATP. P2X receptors are involved in synaptic communication and in diseases of the nervous system. The P2X receptor family consists of at least seven isoforms: P2X1-P2X7.1,2,3All P2X subunits can assemble to form homomeric or heteromeric functional channels with the exception of P2X6, which only seems to function as part of a heteromeric complex.4-9The P2X6 receptor assembles to a heteromultimer with two other P2X subunits, P2X2 and P2X4.P2RX6 is extensively expressed throughout the central nervous system.7

Applications may also work in :

IC IF IFC IHC WB

Supplier :

Alomone Labs

Target :

P2RX6, P2X purinoceptor 6, P2XM, Purinergic receptor P2X-like 1, P2RXL1

Short Description :

A Rabbit Polyclonal Antibody to P2X6 Receptor

Long Description :

Anti-P2X6 Receptor Antibody (#APR-013) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunohistochemistry, immunocytochemistry, and indirect flow cytometry applications. It has been designed to recognize P2RX6 from human, mouse, and rat samples.

Negative Control :

BLP-PR013

Positive Control :

Synonyms :

P2RX6, P2X purinoceptor 6, P2XM, Purinergic receptor P2X-like 1, P2RXL1

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot

Specifictiy :

P2RX6

Form :

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.

Comment :

Contact Alomone Labs for technical support and product customization

Species reactivity key :

H- Human, M- Mouse, R- Rat

Is Toxin :

Purity :

Affinity purified on immobilized antigen.

UNSPSC :

41116161

Clone :

Standard quality control of each lot :

Western blot analysis

Antigen preadsorption control :

1 µg peptide per 1 µg antibody

Application Dilutions: Immunohistochemis ... :

1:200

Application Dilutions: Western blot wb :

1:200

more info or order :

Alomone Labs product webpage