Anti-Mouse KV1.7 (KCNA7) Antibody | Alomone Labs APC-063 product information

product summary

company name :

Alomone Labs

product type :

antibody

product name :

Anti-Mouse KV1.7 (KCNA7) Antibody

catalog :

APC-063

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

reactivity :

mouse, rat

application :

western blot

more info or order :

Alomone Labs product webpage

citations: 2

Reference
Bhandari P, Vandael D, Fernández Fernández D, Fritzius T, Kleindienst D, Önal C, et al. GABAB receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals. elife. 2021;10: pubmed publisher
Durchschein F, Eherer A, Grill M, Sturm E, Pommer V, Langner C, et al. Involvement of EP2 and EP4 Receptors in Eosinophilic Esophagitis: A Pilot Study. Dig Dis Sci. 2019;: pubmed publisher

image

image 1 :

Western blot analysis of mouse heart membranes: - 1. Anti-Mouse KV1.7 (KCNA7) Antibody (#APC-063), (1:200).2. Anti-Mouse KV1.7 (KCNA7) Antibody, preincubated with Mouse Kv1.7/KCNA7 Blocking Peptide (#BLP-PC063).

image 2 :

Peptide TTRKAQEIHGKAPG(C) corresponding to amino acid residues 2-15 of mouse KV1.7 (AccessionQ17ST2). Intracellular N-terminus.

image 3 :

Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4)brain membranes: - 12.Anti-ASCT1 (SLC1A4) Antibody(#ANT-081) (1:200).34. Anti-ASCT1 (SLC1A4) Antibody preincubated with the negative control antigen.

product information

CAT :

APC-063

SKU :

APC-063-CF_0.2 ml

Product Name :

Anti-Mouse KV1.7 (KCNA7) Antibody

Group Type :

Antibodies

Product Type :

Antibodies

Clonality :

Polyclonal

Accession :

Q17ST2

Applications :

Reactivity :

Rat

Host :

Rabbit

Blocking Peptide :

BLP-PC063

Homology :

Mouse only

Formulation :

PBS pH7.4

isotype :

Rabbit IgG

Peptide confirmation :

Confirmed by amino acid analysis and mass spectrometry

Reconstitution :

0.2 ml double distilled water (DDW).

Antibody Concentration After Reconstitut ... :

1 mg/ml

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Preservative :

No Preservative

Immunogen Location :

Intracellular, N-terminus

Label :

Unconjugated

Storage Before Reconstitution :

The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

immunogen source species :

Mouse

Sequence :

TTRKAQEIHGKAPG(C), corresponding to amino acid residues 2-15 of mouse KV1.7

Product Page - Scientific background :

The KV1.7 voltage-gated K+ channel, is a member of the Shaker family of K+ channels that today includes eight members (KV1.1-KV1.8). KV1.7 possesses the signature structure of the voltage-dependent K+ channels: six membrane-spanning domains and intracellular N- and C-termini. As with other channels of the Shaker subfamily, KV1.7 can readily form heteromers with other members of the subfamily to compose the tetramer that forms the functional channel.KV1.7 mRNA was found to be expressed mainly in the heart with somewhat lower levels in pancreas and skeletal muscle.The biophysical and pharmacological properties of the KV1.7 channel closely resembles that of the ultra-rapidly activating delayed rectifier (IKur) in cardiac tissue. This current plays a central role in cardiac atrial repolarization that was largely believed to correspond to the activity of the KV1.5 channel. This raises the possibility that the IKur current is the result of a heteromeric KV1.5/KV1.7 channel.

Applications may also work in :

Supplier :

Alomone Labs

Target :

Potassium voltage-gated channel subfamily A member 7

Short Description :

A Rabbit Polyclonal Antibody to KV1.7 (KCNA7) Channel

Long Description :

Anti-Mouse KV1.7 (KCNA7) Antibody (#APC-063) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot analysis. It has been designed to recognize KV1.7 from mouse samples. The antibody will not recognize the protein from human or rat samples.

Negative Control :

BLP-PC063

Positive Control :

Synonyms :

Potassium voltage-gated channel subfamily A member 7

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot

Specifictiy :

KCNA7

AB Specifictiy :

The antibody does not recognize KV1.7 from rat and human samples.

Form :

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.

Comment :

Contact Alomone Labs for technical support and product customization

Species reactivity key :

H- Human, M- Mouse, R- Rat

Is Toxin :

Purity :

Affinity purified on immobilized antigen.

UNSPSC :

41116161

Clone :

Standard quality control of each lot :

Western blot analysis

Antigen preadsorption control :

1 µg peptide per 1 µg antibody

Application Dilutions: Immunohistochemis ... :

Contact Alomone for information

Application Dilutions: Western blot wb :

1:200

more info or order :

Alomone Labs product webpage