Anti-CACNG4 Antibody | Alomone Labs ACC-114 product information

product summary

company name :

Alomone Labs

product type :

antibody

product name :

Anti-CACNG4 Antibody

catalog :

ACC-114

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Alomone Labs product webpage

citations: 1

Reference
Luan C, Ye Y, Singh T, Barghouth M, Eliasson L, Artner I, et al. The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification. Commun Biol. 2019;2:106 pubmed publisher

image

image 1 :

Western blot analysis of rat brain (lanes 1 and 5), mouse brain (lanes 2 and 6), human SH-SY5Y brain neuroblastoma (lanes 3 and 7) and rat PC12 pheochromocytoma adrenal gland (lanes 4 and 8) lysates: - 1-4. Anti-CACNG4 Antibody (#ACC-114), (1:800).5-8. Anti-CACNG4 Antibody, preincubated with CACNG4 Blocking Peptide (#BLP-CC114).

image 2 :

Peptide (C)EKNKELRFKTKRE corresponding to amino acid residues 208-220 of rat CACNG4 (AccessionQ8VHW9). Intracellular C-terminus.

product information

CAT :

ACC-114

SKU :

ACC-114-CF_0.2 ml

Product Name :

Anti-CACNG4 Antibody

Group Type :

Antibodies

Product Type :

Antibodies

Clonality :

Polyclonal

Accession :

Q8VHW9

Applications :

IC WB

Reactivity :

Human Rat Mouse

Host :

Rabbit

Blocking Peptide :

BLP-CC114

Homology :

Mouse, human - identical

Formulation :

PBS pH7.4

isotype :

Rabbit IgG

Peptide confirmation :

Confirmed by amino acid analysis and mass spectrometry

Reconstitution :

0.2 ml double distilled water (DDW).

Antibody Concentration After Reconstitut ... :

1 mg/ml

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Preservative :

No Preservative

Immunogen Location :

Intracellular, C-terminus

Label :

Unconjugated

Storage Before Reconstitution :

The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

immunogen source species :

Rat

Sequence :

(C)EKNKELRFKTKRE, corresponding to amino acid residues 208-220 of rat CACNG4

Product Page - Scientific background :

Voltage dependent Ca2+ channels (CaV channels) are pivotal players in many physiological roles such as secretion, contraction migration and excitation1.They are composed of several subunits; α1, β, α2δ and γ. CaV channels were originally divided into six physiological types: L, N, P, Q, R, and T type2.L-type calcium channels are composed of five subunits. CaVγ4, represents one of these subunits, and is one of several γ subunit proteins. It is an integral membrane protein that is thought to stabilize the Ca2+ channel in an inactive (closed) state. The encoding gene is a member of the neuronal Ca2+ channel γ subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes3.CaVγ4, along with CaVγ2, CaVγ3 and CaVγ8 have been associated with AMPA receptors and have been shown to modulate the trafficking of receptors to the plasma membrane as well as electrophysiological key properties4.

Applications may also work in :

IC WB

Supplier :

Alomone Labs

Target :

CaVγ4, Voltage-dependent calcium channel gamma-4 subunit, TARP gamma-4, Transmembrane AMPAR regulatory protein gamma-4

Short Description :

A Rabbit Polyclonal Antibody to CACNG4 (CaVγ4) Subunit

Long Description :

Anti-CACNG4 Antibody (#ACC-114) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunocytochemistry applications. It has been designed to recognize CaVγ4 from rat, mouse, and human samples.

Negative Control :

BLP-CC114

Positive Control :

Synonyms :

CaVγ4, Voltage-dependent calcium channel gamma-4 subunit, TARP gamma-4, Transmembrane AMPAR regulatory protein gamma-4

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot

Specifictiy :

CACNG4

Form :

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.

Comment :

Contact Alomone Labs for technical support and product customization

Species reactivity key :

H- Human, M- Mouse, R- Rat

Is Toxin :

Purity :

Affinity purified on immobilized antigen.

UNSPSC :

41116161

Clone :

Standard quality control of each lot :

Western blot analysis

Antigen preadsorption control :

1 µg peptide per 1 µg antibody

Application Dilutions: Immunohistochemis ... :

Contact Alomone for information

Application Dilutions: Western blot wb :

1:800

more info or order :

Alomone Labs product webpage