Anti-CACNG3 Antibody | Alomone Labs ACC-113 product information

product summary

company name :

Alomone Labs

product type :

antibody

product name :

Anti-CACNG3 Antibody

catalog :

ACC-113

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Alomone Labs product webpage

image

image 1 :

Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and human neuroblastoma (SH-SY5Y) cells (lanes 3 and 6): - 1-3. Anti-CACNG3 Antibody (#ACC-113), (1:1000).4-6. Anti-CACNG3 Antibody, preincubated with CACNG3 Blocking Peptide (#BLP-CC113).

image 2 :

Expression of GKAP in rat hippocampus - Immunohistochemical staining of perfusion-fixed frozen rat brain sections withAnti-DLGAP1/GKAP Antibody(#APZ-041) (1:200) followed by goat anti-rabbit-AlexaFluor-488. GKAP staining (green) in hippocampal CA3 region is detected in neurons (arrows) of CA3 pyramidal layer (P). Cell nuclei are stained with DAPI (blue).

product information

CAT :

ACC-113

SKU :

ACC-113-CF_0.2 ml

Product Name :

Anti-CACNG3 Antibody

Group Type :

Antibodies

Product Type :

Antibodies

Clonality :

Polyclonal

Accession :

Q8VHX0

Applications :

Reactivity :

Human Rat Mouse

Host :

Rabbit

Blocking Peptide :

BLP-CC113

Homology :

Mouse - identical, human - 12/14 amino acid residues identical

Formulation :

PBS pH7.4

isotype :

Rabbit IgG

Peptide confirmation :

Confirmed by amino acid analysis and mass spectrometry

Reconstitution :

0.2 ml double distilled water (DDW).

Antibody Concentration After Reconstitut ... :

1 mg/ml

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Preservative :

No Preservative

Immunogen Location :

Intracellular, C-terminus

Label :

Unconjugated

Storage Before Reconstitution :

The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

immunogen source species :

Rat

Sequence :

(C)RSHSELLKKSTFAR, corresponding to amino acid residues 210-223 of rat CACNG3

Product Page - Scientific background :

Voltage-gated Ca2+ (CaV) channels are ubiquitously expressed and function as Ca2+ conducting pores in the plasma membrane1. Based on their electrophysiological and pharmacological properties, Ca2+ channels have traditionally been classified into L, T, N, P/Q, and R types2.L-type calcium channels are heteromultimers composed of four independently encoded proteins, the pore-forming α1 subunit, which triggers Ca2+ flow across the membrane, and the subunits α2δ, γ, and β3.The γ subunit is an integral membrane protein. The γ family consists of at least 8 members, which share a number of common structural features. Each member is predicted to possess four transmembrane domains, with intracellular N- and C-termini. The first extracellular loop contains a highly conserved N-glycosylation site and a pair of conserved cysteine residues5. CaVγ subunits inhibit CaV channel activity and modulate its activation and inactivation kinetics. CaVγ subunits have little effect on CaV channel trafficking4. CaVγ3 mRNAs are only detectable in mouse brain6.

Applications may also work in :

Supplier :

Alomone Labs

Target :

CaVγ3, Voltage-dependent calcium channel gamma-3 subunit, TARP gamma-3, Transmembrane AMPAR regulatory protein gamma-3

Short Description :

A Rabbit Polyclonal Antibody to CACNG3 (CaVγ3) Subunit

Long Description :

Alomone Labs is pleased to offer a highly specific antibody directed against an epitope of rat TARP gamma-3 (CaVγ3, CACNG3). Anti-CACNG3 Antibody (#ACC-113) can be used in western blot analysis. It has been designed to recognize TARP gamma-3 from rat, mouse and human samples.

Negative Control :

BLP-CC113

Positive Control :

Synonyms :

CaVγ3, Voltage-dependent calcium channel gamma-3 subunit, TARP gamma-3, Transmembrane AMPAR regulatory protein gamma-3

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot

Specifictiy :

CACNG3

Form :

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.

Comment :

Contact Alomone Labs for technical support and product customization

Species reactivity key :

H- Human, M- Mouse, R- Rat

Is Toxin :

Purity :

Affinity purified on immobilized antigen.

UNSPSC :

41116161

Clone :

Standard quality control of each lot :

Western blot analysis

Antigen preadsorption control :

1 µg peptide per 1 µg antibody

Application Dilutions: Immunohistochemis ... :

Contact Alomone for information

Application Dilutions: Western blot wb :

1:1000

more info or order :

Alomone Labs product webpage