(S)-AMPA | Alomone Labs A-267 product information

product summary

company name :

Alomone Labs

product type :

chemical

product name :

(S)-AMPA

catalog :

A-267

more info or order :

Alomone Labs product webpage

image

image 1 :

Alomone Labs Ro46-8443inhibits ETB receptor-mediated Ca2+mobilization in CHO cells. - Dose response plot ofRo46-8443(#R-185) inhibition of the ET-B receptor-mediated endothelin-1-evoked Ca2+mobilization (IC50= 0.88 M). Cells were loaded with Calcium 6 dye incubated with Ro46-8443 and stimulated with 30 nM endothelin-1 (EC80). Changes in intracellular Ca2+levels were detected as changes in maximum relative fluorescence (RLU) using FLIPRTETRA?.

product information

CAT :

A-267

SKU :

A-267_1 mg

Product Name :

(S)-AMPA

Group Type :

Non Antibodies

Product Type :

S. Molecules

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

Product Page - Scientific background :

(S)-AMPA enantiomer is a synthetic AMPA receptor agonist. The compound mimics the effects of the glutamate neurotransmitter1.Ionotropic glutamate AMPA receptors (AMPARs) are the primary receptors that mediate fast excitatory synaptic transmission in the mammalian brain. The majority of this transmission in the mammalian central nervous system is mediated by the release of glutamate from the presynaptic terminal and its binding to glutamate receptors on the postsynaptic membrane2.

Supplier :

Alomone Labs

Target :

AMPA receptors

Long Description :

(S)-AMPA (#A-267) is a highly pure, synthetic, and biologically active compound.

Short Description :

An Agonist of AMPA Receptors

MW :

186.17

Synonyms :

(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

Source :

Synthetic

Molecular formula :

C7H10N2O4.

Effective Concentration :

0.01-10 µM.

Activity :

An active enantiomer of AMPA (EC50 = 3.5 μM)1.

Reconstitution and Solubility :

100 mM in H2O. Centrifuge all products before reconstitution (10000 x g 5 min).

Solubility :

100 mM in H2O. Centrifuge all products before reconstitution (10000 x g 5 min).

Storage of solutions :

Up to four weeks at 4°C or three months at -20°C. It is recommended to aliquot reconstituted stock solutions.

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.

Purity :

>99% (HPLC)

CAS No :

83643-88-3

Form :

Lyophilized powder.

Comment :

Contact Alomone Labs for technical support and product customization

UNSPSC :

41116134

Bioassay Tested :

Yes

Chemical Name :

(2S)-2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid.

more info or order :

Alomone Labs product webpage