Tetrodotoxin citrate
Alomone Labs
catalog: T-550
citations: 324


Alomone Labs Tetrodotoxin citrateinhibits native NaVcurrents in ND7-23 cells. - Top: Time course of native inward current amplitude elicited from a holding potential of -100 mV by a 40 ms test pulse to -10 mV delivered every 15 sec. Application of 60 nM Tetrodotoxin citrate(#T-550) is marked in cyan blue. Bottom: Superimposed current traces before (blue) and during (cyan) bath perfusion of 60 nM TTX.
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Tetrodotoxin citrate free
Alomone Labs
catalog: T-500
citations: 23

Alomone Labs Tetrodotoxincitrate free inhibits native NaVcurrents in PC12 and ND7-23cells. - Tetrodotoxincitrate free(#T-500) inhibits PC12 (top) and ND7-23 (bottom) cells at a concentration of 60 nM. Left graphs show the time course of inward current amplitude upon bath application (marked by the horizontal bars) and wash of TTX. Membrane potential was clamped to -120 mV and currents were elicited by 20 ms test pulses to -10 or -20 mV (upper and lower graphs respectively) delivered every 10 sec. Right graphs show the superimposed traces of control current (red) and during perfusion of TTX (black).

Alomone LabsChembridge-5861528inhibitsAllyl isothiocyanate induced calcium signal in TRPA1 expressing cells. - Dose-response curve for the inhibition of human TRPA1 expressing HEK-293 cells loaded with Calcium 5 dye for changes in intracellular Ca2+ measurements. Allyl isothiocyanate (100 M)-induced calcium signal was inhibited by 5 M Chembridge-5861528 (#C-235) with estimated IC50 of about 4 M.
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PF-04856264
Alomone Labs
catalog: P-265
citations: 1
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XEN907
Alomone Labs
catalog: X-105
citations: 1

Alomone Labs (S)-Duloxetine hydrochloride blocks KV4. 3 channels expressed inXenopusoocytes. - A. Time course of KV4.3 current amplitude and inhibition by 100 and 300 M(S)-Duloxetine hydrochloride(#D-170). Currents were elicited by application of voltage step from a holding potential of -80 mV to +20 mV (150 msec) every 10 seconds. B. Superimposed example traces of current responses before and during perfusion of 100 and 300 M (S)-Duloxetine hydrochloride as indicated.
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Co 102862
Alomone Labs
catalog: C-160


Alomone Labs Co 102862 inhibits NaV1.7 channel currents in HEK293cells. - A. Time course of current reversible inhibition by 50 MCo 102862(#C-160). Currents were elicited by a voltage ramp from a holding potential of -100 mV to 60 mV (30 ms) delivered every 10 seconds. B. Example traces of current response to voltage ramp stimulation before and during application of 50 M Co 102862.
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NaV1.7-Compound 36
Alomone Labs
catalog: CMN-003

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KC 12291 hydrochloride
Alomone Labs
catalog: K-105

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N-Me-aminopyrimidinone 9
Alomone Labs
catalog: N-310


Alomone Labs CP 465022 hydrochloride inhibits GluA1 channels expressed inXenopusoocytes. - A. Time course of reversible inhibition by 5 ?M and 25 ?MCP 465022 hydrochloride(#C-335) of glutamate-activated current (100 ?M every 100 s at holding potential -80 mV). B. Superimposed current traces of control and inhibited currents (as indicated) taken from A.
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PF-05089771
Alomone Labs
catalog: P-315

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PF-05241328
Alomone Labs
catalog: P-345


Alomone Labs 7-Chlorokynurenic acid sodium salt inhibits NMDA (NR1+NR2A) receptors expressed inXenopusoocytes. - A. Time course of NMDA currents elicited with 10 M glutamate and 10 M glycine every 50 sec while membrane potential was held at -80 mV. 25 M7-Chlorokynurenic acidsodium salt(#C-286) applied for 2.5 min as indicated inhibited current amplitude. B. Superimposed current traces taken from the experiment described in A.

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PF-05186462
Alomone Labs
catalog: P-365


Alomone Labs PEAQX tetrasodium hydrate inhibits NMDA (NR1+NR2A) receptors expressed inXenopusoocytes. - A. Time course of NMDA currents elicited with 25 M glutamate and 25 M Glycine every 50 sec while membrane potential was held at -80 mV. 0.1 MPEAQX tetrasodium hydrate(#P-255) applied for 2.5 min as indicated inhibited current amplitude. B. Superimposed current traces taken from the experiment described in A.

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