Tetrodotoxin citrate
Alomone Labs
catalog: T-550
citations: 324


Alomone Labs Tetrodotoxin citrateinhibits native NaVcurrents in ND7-23 cells. - Top: Time course of native inward current amplitude elicited from a holding potential of -100 mV by a 40 ms test pulse to -10 mV delivered every 15 sec. Application of 60 nM Tetrodotoxin citrate(#T-550) is marked in cyan blue. Bottom: Superimposed current traces before (blue) and during (cyan) bath perfusion of 60 nM TTX.
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Tetrodotoxin citrate free
Alomone Labs
catalog: T-500
citations: 23

Alomone Labs Tetrodotoxincitrate free inhibits native NaVcurrents in PC12 and ND7-23cells. - Tetrodotoxincitrate free(#T-500) inhibits PC12 (top) and ND7-23 (bottom) cells at a concentration of 60 nM. Left graphs show the time course of inward current amplitude upon bath application (marked by the horizontal bars) and wash of TTX. Membrane potential was clamped to -120 mV and currents were elicited by 20 ms test pulses to -10 or -20 mV (upper and lower graphs respectively) delivered every 10 sec. Right graphs show the superimposed traces of control current (red) and during perfusion of TTX (black).

Alomone LabsChembridge-5861528inhibitsAllyl isothiocyanate induced calcium signal in TRPA1 expressing cells. - Dose-response curve for the inhibition of human TRPA1 expressing HEK-293 cells loaded with Calcium 5 dye for changes in intracellular Ca2+ measurements. Allyl isothiocyanate (100 M)-induced calcium signal was inhibited by 5 M Chembridge-5861528 (#C-235) with estimated IC50 of about 4 M.
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Veratridine
Alomone Labs
catalog: V-110
citations: 4

Alomone Labs Veratridine modulates NaV1.4 Na+currents inXenopusoocytes. - A. Superimposed example current traces of NaV1.4 channels before (black) and during application of 100 ?MVeratridine(#V-110) (green). Note that the current is inhibited during the peak but is enhanced at its end and especially once the membrane potential is back to rest (tail). B. Time course of NaV1.4 channel activity (measured at the tail current) before and during applications of 100 ?M Veratridine (green) and upon wash. Holding potential was -100 mV and currents were elicited every 10 seconds by 100 ms steps to 0 mV.
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4,9-Anhydrotetrodotoxin
Alomone Labs
catalog: T-560
citations: 3
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Co 102862
Alomone Labs
catalog: C-160


Alomone Labs Co 102862 inhibits NaV1.7 channel currents in HEK293cells. - A. Time course of current reversible inhibition by 50 MCo 102862(#C-160). Currents were elicited by a voltage ramp from a holding potential of -100 mV to 60 mV (30 ms) delivered every 10 seconds. B. Example traces of current response to voltage ramp stimulation before and during application of 50 M Co 102862.
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KC 12291 hydrochloride
Alomone Labs
catalog: K-105

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