Tetrodotoxin citrate
Alomone Labs
catalog: T-550
citations: 324


Alomone Labs Tetrodotoxin citrateinhibits native NaVcurrents in ND7-23 cells. - Top: Time course of native inward current amplitude elicited from a holding potential of -100 mV by a 40 ms test pulse to -10 mV delivered every 15 sec. Application of 60 nM Tetrodotoxin citrate(#T-550) is marked in cyan blue. Bottom: Superimposed current traces before (blue) and during (cyan) bath perfusion of 60 nM TTX.
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Tetrodotoxin citrate free
Alomone Labs
catalog: T-500
citations: 23

Alomone Labs Tetrodotoxincitrate free inhibits native NaVcurrents in PC12 and ND7-23cells. - Tetrodotoxincitrate free(#T-500) inhibits PC12 (top) and ND7-23 (bottom) cells at a concentration of 60 nM. Left graphs show the time course of inward current amplitude upon bath application (marked by the horizontal bars) and wash of TTX. Membrane potential was clamped to -120 mV and currents were elicited by 20 ms test pulses to -10 or -20 mV (upper and lower graphs respectively) delivered every 10 sec. Right graphs show the superimposed traces of control current (red) and during perfusion of TTX (black).

Alomone LabsChembridge-5861528inhibitsAllyl isothiocyanate induced calcium signal in TRPA1 expressing cells. - Dose-response curve for the inhibition of human TRPA1 expressing HEK-293 cells loaded with Calcium 5 dye for changes in intracellular Ca2+ measurements. Allyl isothiocyanate (100 M)-induced calcium signal was inhibited by 5 M Chembridge-5861528 (#C-235) with estimated IC50 of about 4 M.
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Co 102862
Alomone Labs
catalog: C-160


Alomone Labs Co 102862 inhibits NaV1.7 channel currents in HEK293cells. - A. Time course of current reversible inhibition by 50 MCo 102862(#C-160). Currents were elicited by a voltage ramp from a holding potential of -100 mV to 60 mV (30 ms) delivered every 10 seconds. B. Example traces of current response to voltage ramp stimulation before and during application of 50 M Co 102862.
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KC 12291 hydrochloride
Alomone Labs
catalog: K-105

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µ-Conotoxin GIIIA
Alomone Labs
catalog: STC-280


Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4)brain membranes: - 12.Anti-SLC6A7 (Proline Transporter) Antibody(#AGT-013) (1:400).34. Anti-SLC6A7 (Proline Transporter) Antibody preincubated with the negative control antigen.

Alomone Labs -Conotoxin GIIIA blocks NaV1.4 currents in Xenopus oocytes. - A. Time course of-Conotoxin GIIIA(#STC-280) action on maximum NaV1.4 current amplitude. Maximum peak current amplitudes were plotted as a function of time. Membrane potential was held at -100 mV and oocytes were stimulated by a 100 ms voltage step to 0 mV. 100 nM -Conotoxin-GIIIA was perfused as indicated by the bar (green) for 5 min. B. Superimposed examples of NaV1.4 channel peak current in the absence (control) and presence (green) of 100 nM -Conotoxin-GIIIA (taken from the experiment in A).
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µ-Conotoxin BuIIIC
Alomone Labs
catalog: STC-690


Alomone LabsGinkgolideB blocks 5-HT3A receptors expressed in HEK 293T cells. - 5-HT3A receptor currents were elicited by 10 M 5-HT delivered every 3 minutes.GinkgolideB(#G-170) was applied 30 seconds before stimulation at 50 200 and 500 M as indicated and inhibited the 5-HT induced current in a dose dependent and reversible manner.

Alomone Labs -Conotoxin BuIIIC blocks NaV1.4 currents expressed in Xenopus oocytes. - A. Time course of-Conotoxin BuIIIC(#STC-690) blocking action on NaV1.4 currents. Peak current amplitude was plotted as a function of time. Membrane potential was held at -100 mV and cells were stimulated by a 100 ms voltage step to -10 mV. 20 nM -Conotoxin BuIIIC were perfused as indicated by the bar (green) during 5 min. B. Superimposed examples of NaV1.4 channel current in the absence (control) and presence (green) of 20 nM -Conotoxin BuIIIC (taken from the experiment in A).
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