This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Agrisera
product type :
antibody
product name :
CO4c Complement component C4c
catalog :
IMS01-031-305
quantity :
100 µl (25.9 mg/ml)
price :
348 USD
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
product information
Product number :
IMS01-031-305
Product name :
CO4c Complement component C4c
Quantity :
100 µl (25.9 mg/ml)
List Price :
348 USD
Immunogen :
Full lenth native CO4c Complement component C4c protein purified from human plasma
Host :
Chicken
Clonality :
Polyclonal
Purity :
Purified, total IgY (chicken egg yolk immunoglobulin) in 0.9% NaCl, 0.02% sodium azide.
Format :
Liquid
Recommended dilutions :
Use at an assay dependent dilution (WB)
Expected apparent MW :
35 kDa
Confirmed reactivity :
Human
Predicted reactivity :
Human
Not reactive in :
No confirmed exceptions from predicted reactivity are currently known.
Additional information :
Only one precipitin arcs in immunodiffusion against normal human serum or human C4. Reacts with α and β chain in electroblotting.The names C4 and C4c for this target protein are frequently used together and almost interchangeably. The difference between the two is a single cleavage and the difference will not be able to be discerned in a polyclonal antibody.
Related products :
Secondary antibodies
Selected references :
Bidula et al. (2013). The role of ficolin-A and lectin complement pathway in the innate defence against pathogenic Aspergillus species. Infect. Immun. March 11.
Background :
Complement component C4 consists of three polypeptide chains (alpha, molecular weight 95 kDa; beta, molecular weight 75 kDa and gamma, molecular weight 33 kDa) and is usually present in serum at 200-600 mg/L. It is a protein of the classical complement pathway. When activated by C1s, peptide C4a is released and the generated C4b binds C2 which is in turn cleaved by C1s to produce the classical pathway C3 convertase, namely C4b2a. C4b also has opsonin activity and binds to macrophages and neutrophils via their CR1 receptor.
Storage :
Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Additional information :
The IgY fraction is isolated by a two-step PEG precipitation, procedure followed by ammonium sulphate precipitation
Commodity Code :
38220000
Our Category :
Immunology
Research area :
Immunology
company information
Agrisera
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.
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