product summary
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company name :
Agrisera
product type :
antibody
product name :
Anti-Histone H2B (Schizosaccharomyces pombe)
catalog :
AS21 4558
quantity :
50 µl
price :
339 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
IgM
reactivity :
human
application :
western blot, chromatin immunoprecipitation
more info or order :
product information
Catalog Number :
AS21 4558
Product Name :
Anti-Histone H2B (Schizosaccharomyces pombe)
Product Type :
Primary antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Clone name :
IgM
Size :
50 µl
List Price (EUR) :
339 USD
list of Pubmed id :
P04913
Product Description :
In the eukaryotic cells, DNA is packaged repetitively into nucleosomes by means of interactions among two molecules of four classes of histone, H2A, H2B, H3 and H4. Each of the histone proteins has an evolutionarily conserved amino-terminal tail that protrudes from the nucleosome. This tail is the target of numerous diverse signaling pathways, resulting in the addition of many post-translational modifications. These modifications include phosphorylation, acetylation, methylation, ADP-ribosylation and mono-ubiquitination. Many important new modifications within the structured core and the carboxy-terminal tail regions of histones are also being identified. It is becoming increasingly clear that these modifications represent crucial regulatory events that govern the accessibility and function of the genome.
CrossReactivity :
Schizosaccharomyces pombe
Background :
In the eukaryotic cells, DNA is packaged repetitively into nucleosomes by means of interactions among two molecules of four classes of histone, H2A, H2B, H3 and H4. Each of the histone proteins has an evolutionarily conserved amino-terminal tail that protrudes from the nucleosome. This tail is the target of numerous diverse signaling pathways, resulting in the addition of many post-translational modifications. These modifications include phosphorylation, acetylation, methylation, ADP-ribosylation and mono-ubiquitination. Many important new modifications within the structured core and the carboxy-terminal tail regions of histones are also being identified. It is becoming increasingly clear that these modifications represent crucial regulatory events that govern the accessibility and function of the genome.
Immunogen :
Synthetic peptide corresponding to N-terminal Schizosaccharomyces pombe histone H2B, SAAEKKPASKAPAGKA, UniProt: P04913
Purity :
Serum. Contains 0.05% sodium azide.
Uses :
Chromatin immunoprecipitation (ChIP), Western blot (WB)
Application Summary :
Chromatin immunoprecipitation (ChIP), Western blot (WB)
Storage :
Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
more info or order :
company information

Agrisera
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.
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