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company name :
Agrisera
product type :
antibody
product name :
Anti-H3R17me2(asym) Histone H3 (asym-dimethyl Arg17)
catalog :
AS16 3180
quantity :
50 µg
price :
539 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, chromatin immunoprecipitation
more info or order :
Agrisera product webpage
product information
Catalog Number :
AS16 3180
Product Name :
Anti-H3R17me2(asym) Histone H3 (asym-dimethyl Arg17)
Product Type :
Primary antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Size :
50 µg
List Price (EUR) :
539 USD
list of Pubmed id :
Q71DI3
Product Description :
Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine. In particular, dimetylation of H3 Arg17 (H3 R17Me2) has been linked to gene activation. Coactivator-associated arginine methyltransferase-1 (CARM1) methylates Arg17 with its protein arginine methyltransferase (PRMT) catalytic core. Activation of this modification is linked to transcription hormone response promotors, as well as cell fate regulation. Interestingly, H3 methylation of R17 and R26 contributes to greater pluripotency potential of stem cells, while downregulation of this PTM increases differentiation.
CrossReactivity :
Caenorhabditis elegans, Human
Background :
Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine. In particular, dimetylation of H3 Arg17 (H3 R17Me2) has been linked to gene activation. Coactivator-associated arginine methyltransferase-1 (CARM1) methylates Arg17 with its protein arginine methyltransferase (PRMT) catalytic core. Activation of this modification is linked to transcription hormone response promotors, as well as cell fate regulation. Interestingly, H3 methylation of R17 and R26 contributes to greater pluripotency potential of stem cells, while downregulation of this PTM increases differentiation.
Immunogen :
KLH-conjugated synthetic peptide
Purity :
Immunogen affinity purified serum.
Uses :
Chromatin immunoprecipitation (ChIP), Immunofluorescence (IF), Western blot (WB)
Application Summary :
Chromatin immunoprecipitation (ChIP), Immunofluorescence (IF), Western blot (WB)
Storage :
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
more info or order :
Agrisera product webpage
company information
Agrisera
Box 57
911 21 Vannas
info@agrisera.com
https://www.agrisera.com
46 935-330000
headquarters: Sweden
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.