product summary
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company name :
Agrisera
product type :
antibody
product name :
mAB-M Mouse anti-human Abeta protein (3-10) region, oligomer-specific (clone 2D10.F6)
catalog :
AS13 2716
quantity :
50 µg
price :
597 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2D10.F6
more info or order :
Agrisera product webpage
citations: 2
Reference
Meilandt W, Maloney J, Imperio J, Lalehzadeh G, Earr T, Crowell S, et al. Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ. Alzheimers Res Ther. 2019;11:97 pubmed publisher
Brannstrom K, Lindhagen Persson M, Gharibyan A, Iakovleva I, Vestling M, Sellin M, et al. A generic method for design of oligomer-specific antibodies. PLoS ONE. 2014;9:e90857 pubmed publisher
product information
Catalog Number :
AS13 2716
NY :
NEJ
Product Name :
mAB-M Mouse anti-human Abeta protein (3-10) region, oligomer-specific (clone 2D10.F6)
Product Type :
Primary
Host Species :
Mouse
Clonality :
Monoclonal
Conjugation :
Unconjugated
Clone Name :
clone 2D10.F6
Size :
50 µg
List Price :
597 USD
Background :
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people, A hallmark of AD is the accumulation of plaques in the brain of AD patients, The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein, Recent findings however suggest that smaller oligomeric forms of Abeta, formed in parallel to the amyloid plaques, excert the predominant tissue damaging effect,Specific identification of the oligomeric forms is as a consequence of great interest, Based on a recently published technique a highly oligomer-specific antibody (mAB-M), targeting Abeta oligomers while omitting reactivity towards the monomeric and fibrillar counterpart, has been developed,
Immunogen :
synthetic peptide chosen from human Abeta protein (3-10) pregion, oligomer specific
Purity :
Affinity purified in PBS pH 7,4, no preservatives
Storage :
For short time storage please add sodium azide and srote at +4°C,For long time storage store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles, Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes,
more info or order :
Agrisera product webpage
company information
Agrisera
Box 57
911 21 Vannas
info@agrisera.com
https://www.agrisera.com
46 935-330000
headquarters: Sweden
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.