This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Agrisera
product type :
antibody
product name :
A1M Human alpha-1-microglobulin
catalog :
AS13 2670
quantity :
100 µg
price :
387 USD
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
application :
western blot, ELISA, radioimmunoassay
product information
Product number :
AS13 2670
Product name :
A1M Human alpha-1-microglobulin
Quantity :
100 µg
List Price :
387 USD
Immunogen :
Full-length human alpha-1-microglobulin (A1M), purified from human urine,
Host :
Chicken
Clonality :
Polyclonal
Purity :
Purified, total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.
Format :
Liquid
Tested applications :
ELISA (ELISA), Radioimmunoassay (RIA), Western blot (WB)
Recommended dilutions :
1 : 5000 (ELISA), 1 : 2000 (WB)
Expected apparent MW :
27 kDa
Confirmed reactivity :
Human
Predicted reactivity :
Human, Rabbit, Cat, Rat, Macaca fascicularis, Pan troglodytes, Gorilla, Ailuropoda melanoleuca
Not reactive in :
No confirmed exceptions from predicted reactivity are currently known.
Related products :
Secondary antibodies
Selected references :
Rutardottir et al. (2016). The cysteine 34 residue of A1M/α1-microglobulin is essential for protection of irradiated cell cultures and reduction of carbonyl groups. Free Radic Res. 2013 Jul;47(6-7):541-50. doi: 10.3109/10715762.2013.801555. Epub 2013 May 29.Olsson MG et al. (2013). The radical-binding lipocalin A1M binds to a Complex I subunit and protects mitochondrial structure and function. Antioxid Redox Signal. 2013 Jun 1;18(16):2017-28.
Background :
Alpha-1-microglobulin is a 27-kDa glycoprotein with immunosuppressive properties. A gene AMBP in the lipocalin cluster encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Alpha-1-microglobulin is found in blood and in connective tissue in most organs. It is most abundant at interfaces between the cells of the body and the environment, such as in lungs, intestine, kidneys and placenta. Alpha 1-microglobulin is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.
Storage :
Store lyophilized/reconstituted at -20°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Additional information :
IgY concentration is 19,8 mg/ml
Commodity Code :
38220000
Our Category :
Other proteins
Research area :
Proteomics
company information
Agrisera
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.
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