product summary
Loading...
company name :
Agrisera
product type :
antibody
product name :
Anti-Amyloid beta oligomer-specific monoclonal antibody (OMAB), Biotinylated
catalog :
AS10 932B
quantity :
50 µg
price :
662.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
IgM
application :
ELISA, immunohistochemistry
more info or order :
citations: 1
product information
Catalog Number :
AS10 932B
Product Name :
Anti-Amyloid beta oligomer-specific monoclonal antibody (OMAB), Biotinylated
Product Type :
Primary antibody
Host Species :
Mouse
Clonality :
Monoclonal
Size :
50 µg
List Price :
662.00 USD
Product Description :
Soluble oligomeric assemblies of the Amyloid-β peptide are today anticipated to be the direct cause regarding the Alzheimer pathology. As a consequence, oligomeric Aβ-assemblies constitute a very interesting therapeutic target. Identification of Aβ-oligomers is however, technically challenging due to there labile nature and low abundance. Abeta oligomer-specific OMAB antibody is based on the IgM isotype and represents a new concept of Aβ-oligomer binders using a combination of high avidity and very low monovalent affinity. This combination creates a selectivity of the antibody towards the oligomeric fraction and minimizes reactivity towards monomeric species.
CrossReactivity :
Human Abeta oligomers only
Background :
Soluble oligomeric assemblies of the Amyloid-β peptide are today anticipated to be the direct cause regarding the Alzheimer pathology. As a consequence, oligomeric Aβ-assemblies constitute a very interesting therapeutic target. Identification of Aβ-oligomers is however, technically challenging due to there labile nature and low abundance. Abeta oligomer-specific OMAB antibody is based on the IgM isotype and represents a new concept of Aβ-oligomer binders using a combination of high avidity and very low monovalent affinity. This combination creates a selectivity of the antibody towards the oligomeric fraction and minimizes reactivity towards monomeric species.
Immunogen :
Partly aggregated, recombinant peptide corresponding to the human Abeta (1-40). Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V.
Purity :
Affinity purified in PBS pH 7.4.
Uses :
ELISA (ELISA), Immunohistochemistry (IHC)
Application Summary :
ELISA (ELISA), Immunohistochemistry (IHC)
Storage :
Store lyophilized/reconstituted at 4°C. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
more info or order :
company information
Agrisera
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.