This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Agrisera
product type :
antibody
product name :
GDE / AGL Glycogen debranching enzyme
catalog :
AS09 454
quantity :
200 µg
price :
424 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 2
Reference
Sottnik J, Mallaredy V, Chauca Diaz A, Ritterson Lew C, Owens C, Dancik G, et al. Elucidating the role of Agl in bladder carcinogenesis by generation and characterization of genetically engineered mice. Carcinogenesis. 2019;40:194-201 pubmed publisher
Oldenburg D, Ru Y, Weinhaus B, Cash S, Theodorescu D, Guin S. CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL). BMC Cancer. 2016;16:713 pubmed publisher
product information
Product number :
AS09 454
Product name :
GDE / AGL Glycogen debranching enzyme
Quantity :
200 µg
List Price :
424 USD
Immunogen :
KLH-conjugated peptide derived from the sequence of human glycogen debranching enzyme UniProt: P35573
Host :
Rabbit
Clonality :
Polyclonal
Purity :
Immunogen affinity purified serum in PBS pH 7.4.
Format :
Lyophilized
Tested applications :
Immunoprecipitation (IP), Western blot (WB)
Recommended dilutions :
5 µg (IP), 1 : 2000 (WB)
Expected apparent MW :
175 kDa
Confirmed reactivity :
Human, Mouse, Rabbit, Rat
Predicted reactivity :
Dog
Not reactive in :
No confirmed exceptions from predicted reactivity are currently known.
Related products :
Secondary antibodies
Selected references :
Sottnik et al. (2018). Elucidating the role of Agl in bladder carcinogenesis by generation and characterization of genetically engineered mice. Carcinogenesis. 2018 Nov 7. doi: 10.1093/carcin/bgy139.Richmond et al. (2018). Glycogen debranching enzyme (AGL) is a novel regulator of non-small cell lung cancer growth. Oncotarget, 2018, Vol. 9, (No. 24), pp: 16718-16730.Oldenburg et al. (2016). CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL). BMC Cancer. 2016 Sep 5;16:713. doi: 10.1186/s12885-016-2756-5.Pagliarani et al. (2014). Glycogen storage disease type III: A novel Agl knockout mouse model. Biochim Biophys Acta. 2014 Aug 1. pii: S0925-4439(14)00250-6. doi: 10.1016/j.bbadis.2014.07.029.
Background :
Synonymes:Glycogen debrancher, 4-alpha-glucanotransferase (EC=2.4.1.25), Oligo-1,4-1,4-glucantransferase, amylo-alpha-1,6-glucosidase, amylo-1,6-glucosidase (EC=3.2.1.33), Dextrin 6-alpha-D-glucosidase,amylo-1, 6-glucosidase, 4-alpha-glucanotransferase
Reconstitution :
For reconstitution add 200 µl of sterile water
Storage :
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Additional information :
This antibody can detect GDE in crude tissue homogenate in both, liver and muscle tissue and is able to immunoprecipiate GDE.Antibody will work as an excellent marker for glycogen. In tissues with no glycogen extression there will be no signal using this antibody.
UniProt number :
P35573
Commodity Code :
38220000
Our Category :
Other proteins
Research area :
Proteomics
company information
Agrisera
Box 57
911 21 Vannas
info@agrisera.com
https://www.agrisera.com
46 935-330000
headquarters: Sweden
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.