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company name :
Agrisera
product type :
antibody
product name :
IAPP Human IAPP (amylin) 1-37, specific for the native hormone having a disulphide-bridge between Cys2-Cys7
catalog :
AS08 359
quantity :
50 µl
price :
302 USD
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
application :
western blot, ELISA
more info or order :
product information
Product number :
AS08 359
Product name :
IAPP Human IAPP (amylin) 1-37, specific for the native hormone having a disulphide-bridge between Cys2-Cys7
Quantity :
50 µl
List Price :
302 USD
Special price 2+ units (List Price) :
226
Special price 3+ units (List Price) :
205
Immunogen :
Synthetic peptide corresponding to the human the 37 residue IAPP also known as amylin, The IAPP/amylin peptide contains a disulphide-bridge between Cys2-Cys7 Amino acid sequence: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (disulphide link between Cys2-Cys7)
Host :
Chicken
Clonality :
Polyclonal
Purity :
Purified,total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.
Format :
Lyophilized
Tested applications :
ELISA (ELISA), Western blot (WB)
Recommended dilutions :
1:1000 (WB), 1:1000 (ELISA)
Expected apparent MW :
3,9 kDa
Confirmed reactivity :
Human
Predicted reactivity :
Primates, mouse, rat, dog, seal, Chinese hamster
Not reactive in :
No confirmed exceptions from predicted reactivity are currently known.
Additional information :
Antibody is specific for the native hormone having a disulphide-bridge between Cys2-Cys7
Background :
Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzherimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the deleopment of type 2 diabetes.
Storage :
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Commodity Code :
38220000
Our Category :
Alzheimer's disease
Research area :
Pathology
more info or order :
company information
Agrisera
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.