This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Agrisera
product type :
antibody
product name :
PEN2 gamma-secretase subunit PEN-2
catalog :
AS06 154
quantity :
100 µg
price :
369 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
product information
Product number :
AS06 154
Product name :
PEN2 gamma-secretase subunit PEN-2
Quantity :
100 µg
List Price :
369 USD
Immunogen :
The antibody was raised against the N-terminal eleven residues of human PEN-2. PEN-2 is the smallest component of the multi-protein gamma-secretase complex. Chosen synthetic peptide has been conjugated to KLH
Host :
Rabbit
Clonality :
Polyclonal
Purity :
Immunogen affinity purified serum in PBS pH 7.4.
Format :
Lyophilized
Tested applications :
Western blot (WB)
Recommended dilutions :
1 : 250 (WB)
Expected apparent MW :
15 kDa
Confirmed reactivity :
Human, Mouse, Hamster
Predicted reactivity :
Bovine, Xenopus laevis (Frog), Rat
Not reactive in :
No confirmed exceptions from predicted reactivity are currently known.
Additional information :
Approx, MW of the target protein is 15 kDa, Antibodies recognize also an unknown protein at around 40 kDa
Related products :
Secondary antibodies
Background :
One characteristic feature of Alzheimer 's disease is the deposition of amyloid-beta peptide (Abeta) as amyloid plaques within specific regions of the human brain. Abeta is derived from the amyloid-beta peptide precursor protein (beta-APP) by the intramembranous cleavage activity of gamma-secretase. PEN-2 (Q9NZ42) is a critical component of PS1/gamma secretase (Farmery et al. 2003; Bergman et al. 2004).Alternative name: presenilin enhancer protein 2
Reconstitution :
For reconstitution add 83,3 µl of sterile water
Storage :
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
UniProt number :
Q9NZ42
Commodity Code :
38220000
Our Category :
Alzheimer's disease
Research area :
Pathology
company information
Agrisera
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.
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