product summary
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company name :
Agrisera
product type :
antibody
product name :
Anti-ExoS Exoenzyme S
catalog :
AS05 056
quantity :
100 µl
price :
461 USD
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
reactivity :
Pseudomonas aeruginosa PAO1
application :
western blot
more info or order :
Agrisera product webpage
citations: 2
Reference
Anantharajah A, Buyck J, Sundin C, Tulkens P, Mingeot Leclercq M, Van Bambeke F. Salicylidene Acylhydrazides and Hydroxyquinolines Act as Inhibitors of Type Three Secretion Systems in Pseudomonas aeruginosa by Distinct Mechanisms. Antimicrob Agents Chemother. 2017;61: pubmed publisher
Anantharajah A, Faure E, Buyck J, Sundin C, Lindmark T, Mecsas J, et al. Inhibition of the Injectisome and Flagellar Type III Secretion Systems by INP1855 Impairs Pseudomonas aeruginosa Pathogenicity and Inflammasome Activation. J Infect Dis. 2016;214:1105-16 pubmed publisher
product information
Catalog Number :
AS05 056
Product Name :
Anti-ExoS Exoenzyme S
Product Type :
Primary antibody
Host Species :
Chicken
Clonality :
Polyclonal
Size :
100 µl
List Price (EUR) :
461 USD
list of Pubmed id :
Q51449 , PA3841
Product Description :
Exoenzyme S (ExoS) is a toxin directly translocated into eukaryotic cells by the type III secretory process of Pseudomonas aeruginosa. It is a bi-functional toxin and contain an N-terminal Rho GAP domain that disrupts the actin cytoskeleton and interference of phagocytosis. The C-terminal of ExoS contains an ADP-ribosyltransferase domain, which elicits a cytotoxic phenotype in cultured cells.
CrossReactivity :
Pseudomonas aeruginosa
Background :
Exoenzyme S (ExoS) is a toxin directly translocated into eukaryotic cells by the type III secretory process of Pseudomonas aeruginosa. It is a bi-functional toxin and contain an N-terminal Rho GAP domain that disrupts the actin cytoskeleton and interference of phagocytosis. The C-terminal of ExoS contains an ADP-ribosyltransferase domain, which elicits a cytotoxic phenotype in cultured cells.
Immunogen :
amino acids 366 to 453 of PA3841 of ADP-rbosylating enzyme - Exoenzyme S overexpressed in a GST fusion. Afterwards cleaved with a help of trombin and separated on a polyacrylamide gel. Gel piece has been used for immunizations.
Purity :
Purified, total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.
Uses :
Western blot (WB)
Application Summary :
Western blot (WB)
Storage :
Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
more info or order :
Agrisera product webpage
company information
Agrisera
Box 57
911 21 Vannas
info@agrisera.com
https://www.agrisera.com
46 935-330000
headquarters: Sweden
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.