This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Agrisera
product type :
antibody
product name :
mPGES-1 glutathione dependent prostaglandin E synthase (1ml)
catalog :
AS03 031-1ml
quantity :
1 ml
price :
3430 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
product information
Product number :
AS03 031-1ml
Product name :
mPGES-1 glutathione dependent prostaglandin E synthase (1ml)
Quantity :
1 ml
List Price :
3430 USD
Immunogen :
Recombinant human purified 6-His mPGES-1 O14684
Host :
Rabbit
Clonality :
Polyclonal
Purity :
Serum
Format :
Lyophilized
Tested applications :
Immunohistochemistry (IHC), Western blot (WB)
Recommended dilutions :
1 : 10 000, human and rat samples (WB) 1 :6 000 on mice samples and in sheep seminal vesicles (IHC)
Expected apparent MW :
17 kDa
Confirmed reactivity :
Human, Mouse, Rat, sheep
Predicted reactivity :
Dog, Hamster, Horse
Not reactive in :
No confirmed exceptions from predicted reactivity are currently known.
Additional information :
Antibody is only recognizing mPGES1 not mPGES2 or cPGES
Related products :
Secondary antibodies
Selected references :
Olajide et al. (2014). Picralima nitida seeds suppress PGE2 production by interfering with multiple signalling pathways in IL-1 β-stimulated SK-N-SH neuronal cells. J Ethnopharmacol. 2014 Jan 31. pii: S0378-8741(14)00074-9. doi: 10.1016/j.jep.2014.01.027.Tuure et al. (2014). Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes. Scand J Rheumatol. 2014 Oct 14:1-6.
Background :
mPGES-1 is an inducible glutathione dependent prostaglandin E synthase that converts cyclooxygenase derived PGH2 into PGE2.
Reconstitution :
For reconstitution add 1 ml of sterile water
Storage :
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Additional information :
In our hands this antibody works with fresh frozen sections not in paraffin embeded material in IHCmPGES-1 antibody was characterized using spleen tissue from LPS-induced mPGES-1 knock-out and wild type mice, In spleen tissue from wt mice we observed strong positive staining in macrophage-like cells, while there was no staining for mPGES-1 in ko mice
UniProt number :
O14684
Commodity Code :
38220000
Our Category :
Other proteins
Research area :
Immunology
company information
Agrisera
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.
questions and comments