This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Agrisera
product type :
antibody
product name :
AMBP Alpha-1-microglobulin
catalog :
AS01 014
quantity :
200 µl
price :
369 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, immunocytochemistry, radioimmunoassay
citations: 1
product information
Product number :
AS01 014
Product name :
AMBP Alpha-1-microglobulin
Quantity :
200 µl
List Price :
369 USD
Immunogen :
rat alpha-1-microglobulin, full length, recombinant protein, overexpressed in baculovirus-infected insect cells with N-terminal His-tag
Host :
Rabbit
Clonality :
Polyclonal
Purity :
Serum with 0.04% sodium azide.
Format :
Lyophilized
Tested applications :
Immunocytochemistry (ICC), Radioimmunoassay (RIA), Western blot (WB)
Recommended dilutions :
1 : 5000 (ELISA), 1 : 200 (IHC), 1 : 6000 (RIA), 1 : 2000 (WB)
Expected apparent MW :
27 kDa
Confirmed reactivity :
Rat
Predicted reactivity :
Mouse
Not reactive in :
No confirmed exceptions from predicted reactivity are currently known.
Related products :
Secondary antibodies
Selected references :
Wen et al. (2017). MicroRNA-148b regulates megalin expression and is associated with receptor downregulation in mice with unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2017 Mar 22:ajprenal.00585.2016. doi: 10.1152/ajprenal.00585.2016.Ostendorf et al. (2006) Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis. J Am Soc Nephrol, 17:1054-62.Sanchez et al. (2002) Expression of the AMBP gene transcript and its two protein products, alpha(1)-microglobulin and bikunin, in mouse embryogenesis. Mech Dev, 117:293-8.
Background :
Alpha-1-microglobulin is a 27-kDa glycoprotein with immunosuppressive properties. A gene AMBP in the lipocalin cluster encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Alpha-1-microglobulin is found in blood and in connective tissue in most organs. It is most abundant at interfaces between the cells of the body and the environment, such as in lungs, intestine, kidneys and placenta. Alpha 1-microglobulin is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.
Reconstitution :
For reconstitution add 200 µl of sterile water
Storage :
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Commodity Code :
38220000
Our Category :
Other proteins
Research area :
Immunology
company information
Agrisera
Agrisera is a Swedish company specializing in polyclonal and monoclonal antibody production, offering primary and secondary antibodies off-the-shelf. Agrisera offers an extensive list of antibodies suitable for detection of plant and algal proteins in a wide range of research areas and applications. They are reactive in thousands of plant and algal species and cited in thousands of scientific articles. Agrisera was awarded as the Plant Science Antibody Supplier of the Year by CiteAB for the company with the most antibody citations for research related to plant science during 2018.
questions and comments