This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5 HA-RagC
catalog :
99718
citations: 4
Reference
Reijnders M, Seibt A, Brügger M, Lamers I, Ott T, Klaas O, et al. De novo missense variants in RRAGC lead to a fatal mTORopathy of early childhood. Genet Med. 2023;25:100838 pubmed publisher
Nardone C, Palanski B, Scott D, Timms R, Barber K, Gu X, et al. A central role for regulated protein stability in the control of TFE3 and MITF by nutrients. Mol Cell. 2023;83:57-73.e9 pubmed publisher
Alesi N, Akl E, Khabibullin D, Liu H, Nidhiry A, Garner E, et al. TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism. Nat Commun. 2021;12:4245 pubmed publisher
Shen K, Choe A, Sabatini D. Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability. Mol Cell. 2017;68:552-565.e8 pubmed publisher
product information
Catalog Number :
99718
Product Name :
pRK5 HA-RagC
article :
doi10.1016/j.molcel.2017.09.026
id28192222
pubmed_id29056322
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
growth strain :
Mammalian expression of HA-RagC
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5SalI
promoterCMV
sequencing_primer_3
sequencing_primer_5ATT TAG GTG ACA CTA TAG
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesGTR2, RAGC, TIB929
geneRRAGC
id64121
genbank_ids
mutation
nameRagC
shRNA_sequence
size
species
tags
locationN terminal on backbone
tagHA
resistance markers :
432
6075
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA