This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
hnRNPA2_LC_WT
catalog :
98657
citations: 6
Reference
Van Lindt J, Lazar T, Pakravan D, Demulder M, Mészáros A, Van Den Bosch L, et al. F/YGG-motif is an intrinsically disordered nucleic-acid binding motif. RNA Biol. 2022;19:622-635 pubmed publisher
Yuan F, Alimohamadi H, Bakka B, Trementozzi A, Day K, Fawzi N, et al. Membrane bending by protein phase separation. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Perdikari T, Murthy A, Ryan V, Watters S, Naik M, Fawzi N. SARS-CoV-2 nucleocapsid protein phase-separates with RNA and with human hnRNPs. EMBO J. 2020;:e106478 pubmed publisher
Ryan V, Watters S, Amaya J, Khatiwada B, Venditti V, Naik M, et al. Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation. Nucleic Acids Res. 2020;48:10542-10554 pubmed publisher
Perdikari T, Murthy A, Ryan V, Watters S, Naik M, Fawzi N. SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins. bioRxiv. 2020;: pubmed publisher
Ryan V, Dignon G, Zerze G, Chabata C, Silva R, Conicella A, et al. Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation. Mol Cell. 2018;69:465-479.e7 pubmed publisher
product information
Catalog Number :
98657
Product Name :
hnRNPA2_LC_WT
article :
doi10.1016/j.molcel.2017.12.022
id28192244
pubmed_id29358076
bacterial resistance :
Kanamycin
cloning :
backbonepJ411
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
growth strain :
Expresses 6xHis-tagged hnRNPA2 AA 190-341
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Unknown
cloning_site_5Unknown
promoter
sequencing_primer_3
sequencing_primer_5
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, OPMD2, RNPA2, SNRPB1
geneHNRNPA2B1
id3181
genbank_ids
NP_002128.1
mutation
namehnRNPA2
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tag6xHis
resistance markers :
3468
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA