This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
c-myc-PT3EF1a
catalog :
92046
citations: 17
Reference
Wu Y, Zhang C, Xiong J, Cai D, Wang C, Liu Y, et al. Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate. Cell Res. 2023;33:835-850 pubmed publisher
Chebotarev A, Ledyaeva V, Patsap O, Ivanov A, Fedotov A, Belousov V, et al. Multimodal label-free imaging of murine hepatocellular carcinoma with a subcellular resolution. J Biophotonics. 2023;16:e202300228 pubmed publisher
Zhu C, Soto Feliciano Y, Morris J, Huang C, Koche R, Ho Y, et al. MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer. elife. 2023;12: pubmed publisher
Kido T, Lau Y. Androgen receptor variant 7 exacerbates hepatocarcinogenesis in a c-MYC-driven mouse HCC model. Oncogenesis. 2023;12:4 pubmed publisher
Mulero S xe1 nchez A, Ramirez C, du Chatinier A, Wang H, Koomen S, Song J, et al. Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma. Mol Oncol. 2023;17:964-980 pubmed publisher
Abakumova T, Vaneev A, Naumenko V, Shokhina A, Belousov V, Mikaelyan A, et al. Intravital electrochemical nanosensor as a tool for the measurement of reactive oxygen/nitrogen species in liver diseases. J Nanobiotechnology. 2022;20:497 pubmed publisher
Feng G, Sun H, Piao M. FBXL6 is dysregulated in keloids and promotes keloid fibroblast growth by inducing c-Myc expression. Int Wound J. 2022;: pubmed publisher
Zheng C, Liang S, Liu B, Liu P, Kwan S, Wolfe S, et al. A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver. Mol Ther. 2022;30:1343-1351 pubmed publisher
Du L, Liu W, Aldana Masangkay G, Pozhitkov A, Pichiorri F, Chen Y, et al. SUMOylation inhibition enhances dexamethasone sensitivity in multiple myeloma. J Exp Clin Cancer Res. 2022;41:8 pubmed publisher
Jin H, Shi Y, Lv Y, Yuan S, Ramirez C, Lieftink C, et al. EGFR activation limits the response of liver cancer to lenvatinib. Nature. 2021;595:730-734 pubmed publisher
Liu P, Liang S, Zheng C, Mintzer E, Zhao Y, Ponnienselvan K, et al. Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice. Nat Commun. 2021;12:2121 pubmed publisher
Jiang T, Sanchez Rivera F, Soto Feliciano Y, Yang Q, Song C, Bhuatkar A, et al. Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function. Hepatology. 2021;74:233-247 pubmed publisher
Shi W, Feng L, Dong S, Ning Z, Hua Y, Liu L, et al. FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1. Cell Commun Signal. 2020;18:100 pubmed publisher
Leibold J, Ruscetti M, Cao Z, Ho Y, Baslan T, Zou M, et al. Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis. Cancer Discov. 2020;10:1038-1057 pubmed publisher
Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, et al. Inducing and exploiting vulnerabilities for the treatment of liver cancer. Nature. 2019;: pubmed publisher
Liu X, Song X, Zhang J, Xu Z, Che L, Qiao Y, et al. Focal adhesion kinase activation limits efficacy of Dasatinib in c-Myc driven hepatocellular carcinoma. Cancer Med. 2018;7:6170-6181 pubmed publisher
Liu P, Ge M, Hu J, Li X, Che L, Sun K, et al. A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis. Hepatology. 2017;66:167-181 pubmed publisher
product information
Catalog Number :
92046
Product Name :
c-myc-PT3EF1a
article :
doi10.1002/hep.29183
id25526
pubmed_id28370287
bacterial resistance :
Ampicillin
cloning :
backbonepT3-EF1a
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
This plasmid is in the OPEN state: there is no stop codon on c-myc.
growth strain :
Expresses c-Myc in mammalian cells
origin :
37
pi :
alt_names
MYC
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoterEF-1a
sequencing_primer_3TAGAAGGCACAGTCGAGG
sequencing_primer_5GAGTTTGGATCTTGGTTCATTC
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMRTL, MYCC, bHLHe39, c-Myc
geneMYC
id4609
genbank_ids
P01106.1
mutation
nameC-MYC
shRNA_sequence
size
species
9606
Homo sapiens
tags
resistance markers :
1021
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA