This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
1014 pcDNA3 T7 Akt1 K179M T308A S473A
catalog :
9031
citations: 7
Reference
Wie J, Liu Z, Song H, Tropea T, Yang L, Wang H, et al. A growth-factor-activated lysosomal K+ channel regulates Parkinson's pathology. Nature. 2021;: pubmed publisher
Zhu L, Yang H, Chao Y, Gu Y, Zhang J, Wang F, et al. Akt phosphorylation regulated by IKKε in response to low shear stress leads to endothelial inflammation via activating IRF3. Cell Signal. 2021;80:109900 pubmed publisher
Swaminathan G, Zhu W, Plowey E. BECN1/Beclin 1 sorts cell-surface APP/amyloid ? precursor protein for lysosomal degradation. Autophagy. 2016;12:2404-2419 pubmed
Jia R, Cao L, Zhang L, Jing W, Chen R, Zhu M, et al. Enhanced myeloid differentiation factor 88 promotes tumor metastasis via induction of epithelial-mesenchymal transition in human hepatocellular carcinoma. Cell Death Dis. 2014;5:e1103 pubmed publisher
Osório C, Chacón P, White M, Kisiswa L, Wyatt S, Rodríguez Tébar A, et al. Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL. Mol Cell Neurosci. 2014;59:24-36 pubmed publisher
Darr J, Klochendler A, Isaac S, Eden A. Loss of IGFBP7 expression and persistent AKT activation contribute to SMARCB1/Snf5-mediated tumorigenesis. Oncogene. 2014;33:3024-32 pubmed publisher
Ramaswamy S, Nakamura N, Vazquez F, Batt D, Perera S, Roberts T, et al. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci U S A. 1999;96:2110-5 pubmed
product information
Catalog Number :
9031
Product Name :
1014 pcDNA3 T7 Akt1 K179M T308A S473A
article :
doi10.1073/pnas.96.5.2110
id351
pubmed_id10051603
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Akt1
Akt
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
geneAKT1
id207
genbank_ids
mutationK179M T308A S473A
nameAkt1 K179M T308A S473A
shRNA_sequence
size1500
species
9606
Homo sapiens
tags
resistance markers :
455
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA