This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK7-HA-S6K1-F5A-E389-R3A
catalog :
8991
citations: 9
Reference
Iezaki T, Horie T, Fukasawa K, Kitabatake M, Nakamura Y, Park G, et al. Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis. Stem Cell Reports. 2018;11:228-241 pubmed publisher
Posada I, Lectez B, Siddiqui F, Oetken Lindholm C, Sharma M, Abankwa D. Opposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1. Sci Rep. 2017;7:8944 pubmed publisher
Erbil S, Oral O, Mitou G, Kig C, Durmaz Timucin E, Guven Maiorov E, et al. RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy. J Biol Chem. 2016;291:16753-65 pubmed publisher
Glanz S, Mirsaidi A, López Fagundo C, Filliat G, Tiaden A, Richards P. Loss-of-Function of HtrA1 Abrogates All-Trans Retinoic Acid-Induced Osteogenic Differentiation of Mouse Adipose-Derived Stromal Cells Through Deficiencies in p70S6K Activation. Stem Cells Dev. 2016;25:687-98 pubmed publisher
Gong Q, Hu Z, Zhang F, Cui A, Chen X, Jiang H, et al. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice. Hepatology. 2016;64:425-38 pubmed publisher
Xiao F, Deng J, Yu J, Guo Y, Chen S, Guo F. A novel function of B-cell translocation gene 1 (BTG1) in the regulation of hepatic insulin sensitivity in mice via c-Jun. FASEB J. 2016;30:348-59 pubmed publisher
Yu J, Xiao F, Zhang Q, Liu B, Guo Y, Lv Z, et al. PRLR regulates hepatic insulin sensitivity in mice via STAT5. Diabetes. 2013;62:3103-13 pubmed publisher
Xiao F, Huang Z, Li H, Yu J, Wang C, Chen S, et al. Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways. Diabetes. 2011;60:746-56 pubmed publisher
Schalm S, Blenis J. Identification of a conserved motif required for mTOR signaling. Curr Biol. 2002;12:632-9 pubmed
product information
Catalog Number :
8991
Product Name :
pRK7-HA-S6K1-F5A-E389-R3A
article :
doi10.1016/S0960-9822(02)00762-5
id344
pubmed_id11967149
bacterial resistance :
Ampicillin
cloning :
backbonepRK7
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
See Schalm et. al., 2005 JBC Vol. 280(12)11101-11106.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5XbaI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesp70 S6K-alpha
geneRps6kb1
id83840
genbank_ids
mutationF5A, T389E, R3A (C-terminal RSPRR motif to ASPAA)
nameS6K1
shRNA_sequence
size1500
species
10116
Rattus norvegicus
tags
locationN terminal on insert
tagHA
resistance markers :
41
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA