This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-myc-FLNa WT
catalog :
8982
citations: 4
Reference
Urra H, Henríquez D, Cánovas J, Villarroel Campos D, Carreras Sureda A, Pulgar E, et al. IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A. Nat Cell Biol. 2018;20:942-953 pubmed publisher
van Vliet A, Giordano F, Gerlo S, Segura I, Van Eygen S, Molenberghs G, et al. The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling. Mol Cell. 2017;65:885-899.e6 pubmed publisher
Wang Q, Zheng W, Wang Z, Yang J, Hussein S, Tang J, et al. Filamin-a increases the stability and plasma membrane expression of polycystin-2. PLoS ONE. 2015;10:e0123018 pubmed publisher
Woo M, Ohta Y, Rabinovitz I, Stossel T, Blenis J. Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin A on an important regulatory site. Mol Cell Biol. 2004;24:3025-35 pubmed
product information
Catalog Number :
8982
Product Name :
pcDNA3-myc-FLNa WT
article :
doi10.1128/MCB.24.7.3025-3035.2004
id343
pubmed_id15024089
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_origin
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Addgene sequencing results find amino acid substitution D2626H compared to reference sequence NP_001447.1.
origin :
37
pi :
alt_names
FLNa
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5HindIII
promoter
sequencing_primer_3pGEX-3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesABP-280, ABPX, CSBS, CVD1, FGS2, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
geneFLNA
id2316
genbank_ids
NP_001447.1
mutation
nameFilamin A
shRNA_sequence
size8640
species
9606
Homo sapiens
tags
locationN terminal on insert
tagmyc
resistance markers :
41
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA