This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-HA-ERK2 WT
catalog :
8974
citations: 12
Reference
Xie M, Wu Z, Ying S, Liu L, Zhao C, Yao C, et al. Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis. Exp Mol Med. 2021;53:572-590 pubmed publisher
Paul T, Roy R, Sarkar R, Sinha S, Biswas N. H2O2 mediated FLIP and XIAP down-regulation involves increased ITCH expression and ERK-Akt crosstalk in imatinib resistant Chronic Myeloid Leukemia cell line K562. Free Radic Biol Med. 2021;166:265-276 pubmed publisher
Du Q, Wang W, Liu T, Shang C, Huang J, Liao Y, et al. High Expression of Integrin α3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer. Front Oncol. 2020;10:36 pubmed publisher
Bunda S, Heir P, Li A, Mamatjan Y, Zadeh G, Aldape K. c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein. Mol Cancer Res. 2020;18:774-786 pubmed publisher
Hiyama A, Morita K, Sakai D, Watanabe M. CCN family member 2/connective tissue growth factor (CCN2/CTGF) is regulated by Wnt-β-catenin signaling in nucleus pulposus cells. Arthritis Res Ther. 2018;20:217 pubmed publisher
Asensio Juan E, Fueyo R, PAPPA S, Iacobucci S, Badosa C, Lois S, et al. The histone demethylase PHF8 is a molecular safeguard of the IFNγ response. Nucleic Acids Res. 2017;45:3800-3811 pubmed publisher
Huang H, Joseph L, Gurin M, Thorp E, Morrow J. Extracellular signal-regulated kinase activation during cardiac hypertrophy reduces sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) transcription. J Mol Cell Cardiol. 2014;75:58-63 pubmed publisher
Heckler M, Thakor H, Schafer C, Riggins R. ERK/MAPK regulates ERR? expression, transcriptional activity and receptor-mediated tamoxifen resistance in ER+ breast cancer. FEBS J. 2014;281:2431-42 pubmed publisher
Martínez López N, ATHONVARANGKUL D, Mishall P, Sahu S, Singh R. Autophagy proteins regulate ERK phosphorylation. Nat Commun. 2013;4:2799 pubmed publisher
Tyagarajan S, Ghosh H, Yevenes G, Imanishi S, Zeilhofer H, Gerrits B, et al. Extracellular signal-regulated kinase and glycogen synthase kinase 3? regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism. J Biol Chem. 2013;288:9634-47 pubmed publisher
Bose A, Janes K. A high-throughput assay for phosphoprotein-specific phosphatase activity in cellular extracts. Mol Cell Proteomics. 2013;12:797-806 pubmed publisher
Dimitri C, Dowdle W, Mackeigan J, Blenis J, Murphy L. Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo. Curr Biol. 2005;15:1319-24 pubmed
product information
Catalog Number :
8974
Product Name :
pcDNA3-HA-ERK2 WT
article :
doi10.1016/j.cub.2005.06.037
id342
pubmed_id16051177
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1
backbone_mutation
backbone_origin
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5KpnI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesERK-2, ERT1, Erk2, p42-MAPK
geneMapk1
id116590
genbank_ids
mutation
nameERK2
shRNA_sequence
size1200
species
10116
Rattus norvegicus
tags
locationN terminal on insert
tagHA
resistance markers :
41
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA