This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Rc/CMV cyclin D2
catalog :
8958
citations: 6
Reference
Joshi J, Xu B, Rubart M, Chang Y, Bao X, Chaliki H, et al. Optogenetic Control of Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Live Mice: A Proof-of-Concept Study. Cells. 2022;11: pubmed publisher
Zhao M, Nakada Y, Wei Y, Bian W, Chu Y, Borovjagin A, et al. Cyclin D2 Overexpression Enhances the Efficacy of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Myocardial Repair in a Swine Model of Myocardial Infarction. Circulation. 2021;144:210-228 pubmed publisher
Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher
Chang Y, Hellwarth P, Randolph L, Sun Y, Xing Y, Zhu W, et al. Fluorescent indicators for continuous and lineage-specific reporting of cell-cycle phases in human pluripotent stem cells. Biotechnol Bioeng. 2020;117:2177-2186 pubmed publisher
Potapova T, Seidel C, Box A, Rancati G, Li R. Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53. Mol Biol Cell. 2016;27:3065-3084 pubmed
Baker G, Landis M, Hinds P. Multiple functions of D-type cyclins can antagonize pRb-mediated suppression of proliferation. Cell Cycle. 2005;4:330-8 pubmed
product information
Catalog Number :
8958
Product Name :
Rc/CMV cyclin D2
article :
doi10.4161/cc.4.2.1485
id337
pubmed_id15684604
bacterial resistance :
Ampicillin
cloning :
backbonepRc/CMV
backbone_mutation
backbone_origin
backbone_size5542
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Full-length cyclin D2 cDNA excised from Bluescript SK+ with NcoI and XbaI and subcloned into Rc/CMV along with a HindIII to NcoI fragment of the cyclin D1 5'UTS that enhances expression. See author's map.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesKIAK0002, MPPH3
geneCCND2
id894
genbank_ids
mutation
namecyclin D2
shRNA_sequence
size1000
species
9606
Homo sapiens
tags
resistance markers :
202
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA