This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
alpha Synuclein-VC
catalog :
89471
citations: 5
Reference
Oh C, Dolatabadi N, Cieplak P, Diaz Meco M, Moscat J, Nolan J, et al. S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia. J Neurosci. 2022;42:3011-3024 pubmed publisher
Albert K, Raymundo D, Panhelainen A, Eesmaa A, Shvachiy L, Araújo G, et al. Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo. Mol Ther. 2021;: pubmed publisher
Wulansari N, Darsono W, Woo H, Chang M, Kim J, Bae E, et al. Neurodevelopmental defects and neurodegenerative phenotypes in human brain organoids carrying Parkinson's disease-linked DNAJC6 mutations. Sci Adv. 2021;7: pubmed publisher
Frey B, AlOkda A, Jackson M, Riguet N, Duce J, Lashuel H. Monitoring alpha-synuclein oligomerization and aggregation using bimolecular fluorescence complementation assays: What you see is not always what you get. J Neurochem. 2020;: pubmed publisher
Outeiro T, Putcha P, Tetzlaff J, Spoelgen R, Koker M, Carvalho F, et al. Formation of toxic oligomeric alpha-synuclein species in living cells. PLoS ONE. 2008;3:e1867 pubmed publisher
product information
Catalog Number :
89471
Product Name :
alpha Synuclein-VC
article :
doi10.1371/journal.pone.0001867
id25238
pubmed_id18382657
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1
backbone_mutation
backbone_origin
backbone_size5690
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
expresses human alpha Synuclein fused to the C-terminal part of Venus
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5AflII
promoterCMV
sequencing_primer_3bGH
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesNACP, PARK1, PARK4, PD1
geneSNCA
id6622
genbank_ids
NM_000345
mutation
nameSNCA
shRNA_sequence
size423
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagC-terminal part of Venus
resistance markers :
3257
3327
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA