This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCI flag PCAF
catalog :
8941
citations: 11
Reference
Kim G, Bhattarai P, Lim S, Lee K, Choi H. Sirtuin 5-mediated deacetylation of TAZ at K54 promotes melanoma development. Cell Oncol (Dordr). 2023;: pubmed publisher
Kong C, Wang D, Wang F, Lv Y, Zhou W, Ye P, et al. PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway. Oxid Med Cell Longev. 2022;2022:1200602 pubmed publisher
Cai W, Su L, Liao L, Liu Z, Langbein L, Dulaimi E, et al. PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth. Nat Commun. 2019;10:5800 pubmed publisher
Savoia M, Cencioni C, Mori M, Atlante S, Zaccagnini G, Devanna P, et al. P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation. FASEB J. 2019;33:4107-4123 pubmed publisher
Karim M, Yoshizawa T, Sobuz S, Sato Y, Yamagata K. Sirtuin 7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR4. Biochem Biophys Res Commun. 2017;490:423-428 pubmed publisher
Kikani C, Wu X, Paul L, Sabic H, Shen Z, Shakya A, et al. Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis. elife. 2016;5: pubmed publisher
Andrews P, Kao K. Wnt/?-catenin-dependent acetylation of Pygo2 by CBP/p300 histone acetyltransferase family members. Biochem J. 2016;473:4193-4203 pubmed
Wright D, Marchal C, Hoang K, Ankney J, Nguyen S, Rushing A, et al. Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. Oncotarget. 2016;7:1687-706 pubmed publisher
North B, Rosenberg M, Jeganathan K, Hafner A, Michan S, Dai J, et al. SIRT2 induces the checkpoint kinase BubR1 to increase lifespan. EMBO J. 2014;33:1438-53 pubmed publisher
Dai M, Al Odaini A, Arakelian A, Rabbani S, Ali S, Lebrun J. A novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGF?-mediated breast cancer cell migration and invasion. Breast Cancer Res. 2012;14:R127 pubmed publisher
Yang X, Ogryzko V, Nishikawa J, Howard B, Nakatani Y. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature. 1996;382:319-24 pubmed
product information
Catalog Number :
8941
Product Name :
pCI flag PCAF
article :
doi10.1038/382319a0
id335
pubmed_id8684459
bacterial resistance :
Ampicillin
cloning :
backbonepCI
backbone_mutation
backbone_origin
backbone_size4000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Compared to GenBank reference sequence NP_003875.3, Serine-2 is actually Valine-2 immediately after the FLAG tag.
origin :
37
pi :
alt_names
P/CAF
cloning
clone_methodRestriction Enzyme
cloning_site_3KpnI
cloning_site_5EcoRI
promoter
sequencing_primer_3EBV-rev
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCAF, P/CAF, PCAF
geneKAT2B
id8850
genbank_ids
NM_003884
mutation
namePCAF
shRNA_sequence
size2579
species
9606
Homo sapiens
tags
locationN terminal on insert
tagflag
resistance markers :
357
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA