This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
FAS promoter luciferase
catalog :
8890
citations: 4
Reference
Li L, Hua L, Fan H, He Y, Xu W, Zhang L, et al. Interplay of PKD3 with SREBP1 Promotes Cell Growth via Upregulating Lipogenesis in Prostate Cancer Cells. J Cancer. 2019;10:6395-6404 pubmed publisher
Shao D, Han J, Hou X, Fry J, Behring J, Seta F, et al. Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. Antioxid Redox Signal. 2017;27:313-327 pubmed publisher
Madsen A, Bozickovic O, Bjune J, Mellgren G, Sagen J. Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). Sci Rep. 2015;5:16430 pubmed publisher
Kim J, Sarraf P, Wright M, Yao K, Mueller E, Solanes G, et al. Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J Clin Invest. 1998;101:1-9 pubmed
product information
Catalog Number :
8890
Product Name :
FAS promoter luciferase
article :
doi10.1172/JCI1411
id317
pubmed_id9421459
bacterial resistance :
Ampicillin
cloning :
backbonen/a
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
-220 to +25 fragment of the Fatty Acid Synthetase promoter with regard to the transcription start site.
origin :
37
pi :
alt_names
FAS promoter
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5KpnI
promoter
sequencing_primer_3LucNrev
sequencing_primer_5EBV-rev
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneFasn
id50671
genbank_ids
mutation
nameFatty Acid Synthetase Promoter
shRNA_sequence
size245
species
10116
Rattus norvegicus
32644
Other
unknown - rat or mouse
tags
locationC terminal on backbone
tagluciferase
resistance markers :
495
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA