This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
3544 pMIG Bcl-2
catalog :
8793
citations: 3
Reference
Falco A, Bartolome Cabrero R, Gascón S. Bcl-2-Assisted Reprogramming of Mouse Astrocytes and Human Fibroblasts into Induced Neurons. Methods Mol Biol. 2021;2352:57-71 pubmed publisher
Lee J, Tang S, Ortiz V, Vo T, Fruman D. MCL-1-independent mechanisms of synergy between dual PI3K/mTOR and BCL-2 inhibition in diffuse large B cell lymphoma. Oncotarget. 2015;6:35202-17 pubmed publisher
Cheng E, Wei M, Weiler S, Flavell R, Mak T, Lindsten T, et al. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol Cell. 2001;8:705-11 pubmed
product information
Catalog Number :
8793
Product Name :
3544 pMIG Bcl-2
article :
doi10.1016/S1097-2765(01)00320-3
id289
pubmed_id11583631
bacterial resistance :
Ampicillin
cloning :
backbonepMIG
backbone_mutation
backbone_origin
backbone_size7000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
Note that the GFP in this plasmid is not fused to gene. It is for selection purposes only. Please note that this plasmid is an extremely slow grower and may take up to 3 days to grow.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoR1
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5pLXSN 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBcl-2, PPP1R50
geneBCL2
id596
genbank_ids
NM_000633
mutation
nameBcl-2
shRNA_sequence
size720
species
9606
Homo sapiens
tags
resistance markers :
264
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA