This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
3336 pcDNA3 Bcl-2
catalog :
8768
citations: 13
Reference
Ebelt N, Zuniga E, Passi K, Sobocinski L, Manuel E. Hyaluronidase-Expressing Salmonella Effectively Targets Tumor-Associated Hyaluronic Acid in Pancreatic Ductal Adenocarcinoma. Mol Cancer Ther. 2019;: pubmed publisher
Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, et al. Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Nat Commun. 2019;10:4710 pubmed publisher
Cheng Y, Li S, Chuang W, Li C, Chen G, Chang C, et al. Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4'-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells. Int J Mol Sci. 2019;20: pubmed publisher
Berrak Ã, Akkoç Y, Arısan E, Çoker Gürkan A, Obakan Yerlikaya P, Palavan Ünsal N. The inhibition of PI3K and NFκB promoted curcumin-induced cell cycle arrest at G2/M via altering polyamine metabolism in Bcl-2 overexpressing MCF-7 breast cancer cells. Biomed Pharmacother. 2016;77:150-60 pubmed publisher
Liu K, Frazier W. Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy. PLoS ONE. 2015;10:e0129667 pubmed publisher
Eichhorn J, Alford S, Sakurikar N, Chambers T. Molecular analysis of functional redundancy among anti-apoptotic Bcl-2 proteins and its role in cancer cell survival. Exp Cell Res. 2014;322:415-24 pubmed publisher
Obakan P, Arisan E, Ozfiliz P, Coker Gurkan A, Palavan Unsal N. Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells. Mol Biol Rep. 2014;41:145-54 pubmed publisher
Eichhorn J, Sakurikar N, Alford S, Chu R, Chambers T. Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death. Cell Death Dis. 2013;4:e834 pubmed publisher
Yang S, Wang H, Wu T, Chen Y, Shieh J, Lin J, et al. Subamolide B Isolated from Medicinal Plant Cinnamomum subavenium Induces Cytotoxicity in Human Cutaneous Squamous Cell Carcinoma Cells through Mitochondrial and CHOP-Dependent Cell Death Pathways. Evid Based Complement Alternat Med. 2013;2013:630415 pubmed publisher
Ferdek P, Gerasimenko J, Peng S, Tepikin A, Petersen O, Gerasimenko O. A novel role for Bcl-2 in regulation of cellular calcium extrusion. Curr Biol. 2012;22:1241-6 pubmed publisher
Lamers F, Schild L, den Hartog I, Ebus M, Westerhout E, Ora I, et al. Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth. Eur J Cancer. 2012;48:3093-103 pubmed publisher
Bhalla S, Evens A, Dai B, Prachand S, Gordon L, Gartenhaus R. The novel anti-MEK small molecule AZD6244 induces BIM-dependent and AKT-independent apoptosis in diffuse large B-cell lymphoma. Blood. 2011;118:1052-61 pubmed publisher
Yamamoto K, Ichijo H, Korsmeyer S. BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol Cell Biol. 1999;19:8469-78 pubmed
product information
Catalog Number :
8768
Product Name :
3336 pcDNA3 Bcl-2
article :
doi
id284
pubmed_id10567572
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
ORF contains SacI, PstI, and BamHI sites sense from T7 direction.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesBcl-2, PPP1R50
geneBCL2
id596
genbank_ids
NM_000633
mutation
nameBcl-2
shRNA_sequence
size720
species
9606
Homo sapiens
tags
resistance markers :
264
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA