This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
3120 pSFFV-neo Bcl-XL
catalog :
8749
citations: 10
Reference
Yu C, Yeung T, Fu W, Poon R. BCL-XL regulates the timing of mitotic apoptosis independently of BCL2 and MCL1 compensation. Cell Death Dis. 2024;15:2 pubmed publisher
Xiao B, Deng X, Lim G, Zhou W, Saw W, Zhou Z, et al. p62-Mediated mitochondrial clustering attenuates apoptosis induced by mitochondrial depolarization. Biochim Biophys Acta Mol Cell Res. 2017;1864:1308-1317 pubmed publisher
Huang S, Tang R, Poon R. BCL-W is a regulator of microtubule inhibitor-induced mitotic cell death. Oncotarget. 2016;7:38718-38730 pubmed publisher
Wang W, Childress M, Geahlen R. Syk interacts with and phosphorylates nucleolin to stabilize Bcl-x(L) mRNA and promote cell survival. Mol Cell Biol. 2014;34:3788-99 pubmed publisher
Li X, Liu Y, Granberg K, Wang Q, Moore L, Ji P, et al. Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma. Oncogene. 2015;34:1619-1628 pubmed publisher
Sarkar S, Azab B, Quinn B, Shen X, Dent P, Klibanov A, et al. Chemoprevention gene therapy (CGT) of pancreatic cancer using perillyl alcohol and a novel chimeric serotype cancer terminator virus. Curr Mol Med. 2014;14:125-40 pubmed
Eichhorn J, Sakurikar N, Alford S, Chu R, Chambers T. Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death. Cell Death Dis. 2013;4:e834 pubmed publisher
Cheng Z, Gong Y, Ma Y, Lu K, Lu X, Pierce L, et al. Inhibition of BET bromodomain targets genetically diverse glioblastoma. Clin Cancer Res. 2013;19:1748-59 pubmed publisher
James M, Wen W, Wang Y, Byers L, Heymach J, Coombes K, et al. Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus. PLoS ONE. 2012;7:e36116 pubmed publisher
Chao D, Linette G, Boise L, White L, Thompson C, Korsmeyer S. Bcl-XL and Bcl-2 repress a common pathway of cell death. J Exp Med. 1995;182:821-8 pubmed
product information
Catalog Number :
8749
Product Name :
3120 pSFFV-neo Bcl-XL
article :
doi10.1084/jem.182.3.821
id273
pubmed_id7650488
bacterial resistance :
Ampicillin
cloning :
backbonepSFFV-neo
backbone_mutation
backbone_origin
backbone_size7200
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5SFFV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52
geneBCL2L1
id598
genbank_ids
NM_138578
mutation
nameBcl-xl
shRNA_sequence
size700
species
9606
Homo sapiens
tags
plasmid copy :
Gabriel Nunez
resistance markers :
264
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA