This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
VN-Tau (wt)
catalog :
87368
citations: 5
Reference
Nishida K, Matsumura K, Tamura M, Nakamichi T, Shimamori K, Kuragano M, et al. Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules' physical properties and neurite morphology. Sci Rep. 2023;13:8870 pubmed publisher
Samluk L, Ostapczuk P, Dziembowska M. Long-term mitochondrial stress induces early steps of Tau aggregation by increasing reactive oxygen species levels and affecting cellular proteostasis. Mol Biol Cell. 2022;33:ar67 pubmed publisher
Choi C, Gwin M, Voth S, Kolb C, Zhou C, Nelson A, et al. Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy. J Biol Chem. 2022;298:101482 pubmed publisher
Moreira G, Cantrelle F, Quezada A, Carvalho F, Cristóvão J, Sengupta U, et al. Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding. Nat Commun. 2021;12:6292 pubmed publisher
Blum D, Herrera F, Francelle L, Mendes T, Basquin M, Obriot H, et al. Mutant huntingtin alters Tau phosphorylation and subcellular distribution. Hum Mol Genet. 2015;24:76-85 pubmed publisher
product information
Catalog Number :
87368
Product Name :
VN-Tau (wt)
article :
doi10.1093/hmg/ddu421
id24991
pubmed_id25143394
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1
backbone_mutation
backbone_origin
backbone_size5642
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Original clone (VN-alpha Synuclein) includes already the N-terminal part of venus, and was a gift from Pamela J.McLean.
growth strain :
expresses hTau fused to the N-terminal part of Venus
origin :
37
pi :
alt_names
Tau
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5AflII
promoterCMV
sequencing_primer_3bGH
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesDDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, Tau-PHF6, tau-40
geneMAPT
id4137
genbank_ids
NM_005910.5
mutation
nameMAPT
shRNA_sequence
size1322
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagN-terminal part of Venus
plasmid copy :
Original clone (VN-alpha-Synuclein) comes from Pamela J.McLean.
resistance markers :
3327
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA