This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Integrin beta 2 - mYFP
catalog :
8638
citations: 5
Reference
Rubio K, Romero Olmedo A, Sarvari P, Swaminathan G, Ranvir V, Rogel Ayala D, et al. Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer. Theranostics. 2023;13:2384-2407 pubmed publisher
Blackburn J, Lau D, Liu E, Ellins J, Vrieze A, Pawlak E, et al. Soluble CD93 is an apoptotic cell opsonin recognized by αx β2. Eur J Immunol. 2019;49:600-610 pubmed publisher
Swaim C, Scott A, Canadeo L, Huibregtse J. Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor. Mol Cell. 2017;68:581-590.e5 pubmed publisher
Luo Y, Jacobs E, Greco T, Mohammed K, Tong T, Keegan S, et al. HIV-host interactome revealed directly from infected cells. Nat Microbiol. 2016;1:16068 pubmed
Kim M, Carman C, Springer T. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science. 2003;301:1720-5 pubmed
product information
Catalog Number :
8638
Product Name :
Integrin beta 2 - mYFP
article :
doi10.1126/science.1084174
id243
pubmed_id14500982
bacterial resistance :
Kanamycin
cloning :
backbonepEYFP N1
backbone_mutation
backbone_originClontech
backbone_size4900
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
CD18
cloning
clone_methodRestriction Enzyme
cloning_site_3AgeI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5EGFP-N
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7
geneITGB2
id3689
genbank_ids
mutationstop codon of beta2 was replaced with AgeI restriction site. Leu221 of YFP was replaced with lysine by PCR to generate monomeric YFP.
nameIntegrin beta 2
shRNA_sequence
size3500
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagYFP
resistance markers :
496
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA