This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pmCherry-Gal3
catalog :
85662
citations: 10
Reference
Rodrigues Lopes I, Alcântara L, Silva R, Josse J, Vega E, Cabrerizo A, et al. Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature. Nat Commun. 2022;13:7174 pubmed publisher
Bai Y, Yu G, Zhou H, Amarasinghe O, Zhou Y, Zhu P, et al. PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805. Autophagy. 2022;:1-20 pubmed publisher
Remy J, Linder B, Weirauch U, Day B, Stringer B, Herold Mende C, et al. STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death. Cancers (Basel). 2022;14: pubmed publisher
Millarte V, Schlienger S, Kälin S, Spiess M. Rabaptin5 targets autophagy to damaged endosomes and Salmonella vacuoles via FIP200 and ATG16L1. EMBO Rep. 2022;23:e53429 pubmed publisher
Hu P, Li H, Sun W, Wang H, Yu X, Qing Y, et al. Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218. Acta Pharm Sin B. 2021;11:3178-3192 pubmed publisher
Sønder S, Häger S, Heitmann A, Frankel L, Dias C, Simonsen A, et al. Restructuring of the plasma membrane upon damage by LC3-associated macropinocytosis. Sci Adv. 2021;7: pubmed publisher
Meyer N, Henkel L, Linder B, Zielke S, Tascher G, Trautmann S, et al. Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death. Autophagy. 2021;:1-20 pubmed publisher
Hu P, Wang J, Qing Y, Li H, Sun W, Yu X, et al. FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation. Cell Death Dis. 2021;12:80 pubmed publisher
Polanco J, Hand G, Briner A, Li C, Götz J. Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol. Acta Neuropathol. 2021;141:235-256 pubmed publisher
Papadopoulos C, Kirchner P, Bug M, Grum D, Koerver L, Schulze N, et al. VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy. EMBO J. 2017;36:135-150 pubmed publisher
product information
Catalog Number :
85662
Product Name :
pmCherry-Gal3
article :
doi10.15252/embj.201695148
id22737
pubmed_id27753622
bacterial resistance :
Kanamycin
cloning :
backbonepmCherry-C1
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
PCR amplification of the Gal3 coding sequence from U2OS cDNA
growth strain :
Fluorescent reporter for lysosomal damage
origin :
37
pi :
alt_names
Galectin-3
Gal3
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5HindIII
promoterCMV
sequencing_primer_3SV40pA-R
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
geneLGALS3
id3958
genbank_ids
NM_002306.3
NM_001177388.1
mutation
nameLGALS3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagmCherry
resistance markers :
335
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA