FgH1tUTG_huMcl-1.1 | Addgene 85530 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

FgH1tUTG_huMcl-1.1

catalog :

85530

citations: 3

Reference
Poohadsuan J, O Doherty G, Owattanapanich W, Kungwankiattichai S, Rojanasakul Y, Issaragrisil S, et al. Cardiac glycoside ouabain efficiently targets leukemic stem cell apoptotic machinery independent of cell differentiation status. Cell Commun Signal. 2023;21:283 pubmed publisher
Luanpitpong S, Poohadsuan J, Samart P, Kiratipaiboon C, Rojanasakul Y, Issaragrisil S. Reactive oxygen species mediate cancer stem-like cells and determine bortezomib sensitivity via Mcl-1 and Zeb-1 in mantle cell lymphoma. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3739-3753 pubmed publisher
Aubrey B, Kelly G, Kueh A, Brennan M, O Connor L, Milla L, et al. An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations inÂ vivo. Cell Rep. 2015;10:1422-32 pubmed publisher

product information

Catalog Number :

85530

Product Name :

FgH1tUTG_huMcl-1.1

article :

doi	10.1016/j.celrep.2015.02.002
id	15928
pubmed_id	25732831

bacterial resistance :

Ampicillin

cloning :

backbone

FUGW

backbone_mutation

backbone_origin

David Baltimore

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Lentiviral

CRISPR

growth strain :

Inducible expression of guide RNA (huMcl-1.1) with fluorescent GFP reporter

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	BsmB1
cloning_site_5	BsmB1
promoter	H1t
sequencing_primer_3
sequencing_primer_5	CAGACATACAAACTAAAGAAT
site_3_destroyed	1
site_5_destroyed	1

entrez_gene

aliases	BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
gene	MCL1
id	4170

genbank_ids

mutation

name

hu Mcl-1.1

shRNA_sequence

TCCCGGAGCTGGACGGGTACGAGC

size

species

9606

Homo sapiens