This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCIpA102-G-HLA-A2_GFP
catalog :
85162
citations: 8
Reference
Bj xf8 rnestad S, Solbakken M, Jakobsen K, Jentoft S, Bakke O, Progida C. Atlantic cod (Gadus morhua) MHC I localizes to endolysosomal compartments independently of cytosolic sorting signals. Front Cell Dev Biol. 2023;11:1050323 pubmed publisher
Joung J, Kirchgatterer P, Singh A, Cho J, Nety S, Larson R, et al. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nat Commun. 2022;13:1606 pubmed publisher
Filali L, Puissegur M, Cortacero K, Cussat Blanc S, Khazen R, Van Acker N, et al. Ultrarapid lytic granule release from CTLs activates Ca2+-dependent synaptic resistance pathways in melanoma cells. Sci Adv. 2022;8:eabk3234 pubmed publisher
Wang Y, Wang X, Cui X, Zhuo Y, Li H, Ha C, et al. Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8+ T cell response in tumor. Sci Adv. 2020;6:eaba5412 pubmed publisher
Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed publisher
Mensali N, Dillard P, Hebeisen M, Lorenz S, Theodossiou T, Myhre M, et al. NK cells specifically TCR-dressed to kill cancer cells. EBioMedicine. 2019;40:106-117 pubmed publisher
Walseng E, Köksal H, Sektioglu I, Fane A, Skorstad G, Kvalheim G, et al. A TCR-based Chimeric Antigen Receptor. Sci Rep. 2017;7:10713 pubmed publisher
Walchli S, Kumari S, Fallang L, Sand K, Yang W, Landsverk O, et al. Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation. Eur J Immunol. 2014;44:774-84 pubmed publisher
product information
Catalog Number :
85162
Product Name :
pCIpA102-G-HLA-A2_GFP
article :
doi10.1002/eji.201343671
id22631
pubmed_id24293164
bacterial resistance :
Ampicillin
cloning :
backbonepCIpA102-GTW(JO249)
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Other
mRNA expression
growth notes :
pCI-A102 constructs were opened with MfeI and used as a template for small-scale mRNA synthesis
growth strain :
for mRNA expression of HLA.A2-EGFP
origin :
37
pi :
alt_names
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3EGFP-N
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHLAA
geneHLA-A
id3105
genbank_ids
mutation
nameHLA.A2
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagEGFP
plasmid copy :
It was cloned from the cDNA of an healthy donor and sequence confirmed as HLA-A*0201
resistance markers :
3132
3133
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA