This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
hAur-A
catalog :
8510
citations: 5
Reference
Duhamel S, Girondel C, Dorn J, Tanguay P, Voisin L, Smits R, et al. Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7?-Aurora A pathway. Cell Cycle. 2016;15:1631-42 pubmed publisher
Rivas S, Armisén R, Rojas D, Maldonado E, Huerta H, Tapia J, et al. The Ski Protein is Involved in the Transformation Pathway of Aurora Kinase A. J Cell Biochem. 2016;117:334-43 pubmed publisher
Oruganty K, Talathi N, Wood Z, Kannan N. Identification of a hidden strain switch provides clues to an ancient structural mechanism in protein kinases. Proc Natl Acad Sci U S A. 2013;110:924-9 pubmed publisher
Grover A, Singh R, Shandilya A, Priyandoko D, Agrawal V, Bisaria V, et al. Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity. PLoS ONE. 2012;7:e30890 pubmed publisher
Crane R, Kloepfer A, Ruderman J. Requirements for the destruction of human Aurora-A. J Cell Sci. 2004;117:5975-83 pubmed
product information
Catalog Number :
8510
Product Name :
hAur-A
article :
doi10.1242/jcs.01418
id215
pubmed_id15536123
bacterial resistance :
Ampicillin
cloning :
backbonepBABE-puro
backbone_mutation
backbone_origin
backbone_size5169
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
See author's map. For production of retrovirus expressing human Aur-A wild-type. (Ruderman RC232)
origin :
37
pi :
alt_names
Aurora A
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5pBABE 5'
site_3_destroyed1
site_5_destroyed
entrez_gene
aliasesAIK, ARK1, AURA, BTAK, PPP1R47, STK15, STK6, STK7
geneAURKA
id6790
genbank_ids
mutation
namehAur-A
shRNA_sequence
size1200
species
9606
Homo sapiens
tags
resistance markers :
429
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA