This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3.2 TDP-43 NLS1 YFP
catalog :
84912
citations: 3
Reference
Licht Murava A, Meadows S, Palaguachi F, Song S, Jackvony S, Bram Y, et al. Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines. Sci Adv. 2023;9:eade1282 pubmed publisher
Mann J, Gleixner A, Mauna J, Gomes E, DeChellis Marks M, Needham P, et al. RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron. 2019;102:321-338.e8 pubmed publisher
Elden A, Kim H, Hart M, Chen Plotkin A, Johnson B, Fang X, et al. Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature. 2010;466:1069-75 pubmed publisher
product information
Catalog Number :
84912
Product Name :
pcDNA3.2 TDP-43 NLS1 YFP
article :
doi10.1038/nature09320
id22579
pubmed_id20740007
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.2 DEST
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Mammalian expresion of TDP-43 NLS1 YFP
origin :
37
pi :
alt_names
TARDBP
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3TK-pA-R
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesALS10, TDP-43
geneTARDBP
id23435
genbank_ids
mutationK82A, R83A, K84A
nameTDP-43
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagYFP
resistance markers :
166
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA