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product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV-VSV-G
catalog :
8454
citations: 664
Reference
Mohallem R, Aryal U. Nuclear phosphoproteome reveals Prolyl Isomerase PIN1 as a modulator of oncogene-induced senescence. Mol Cell Proteomics. 2024;:100715 pubmed publisher
Tarallo D, Mart xed nez J, Leyva A, M xf3 naco A, Perroni C, Tassano M, et al. Mitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after chemotherapy. Sci Rep. 2024;14:909 pubmed publisher
Xiao Y, Wu Y, Tang W. An adenine base editor variant expands context compatibility. Nat Biotechnol. 2024;: pubmed publisher
Hosawi M, Cheng J, Fankhaenel M, Przewloka M, Elias S. Interplay between the plasma membrane and cell-cell adhesion maintains epithelial identity for correct polarised cell divisions. J Cell Sci. 2024;137: pubmed publisher
Rigaux E, Chen J, George F, Lemaire J, Bertrand C, Faugeras L, et al. Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids. Curr Protoc. 2023;3:e943 pubmed publisher
Klaihmon P, Luanpitpong S, Kang X, Issaragrisil S. Anti-TIM3 chimeric antigen receptor-natural killer cells from engineered induced pluripotent stem cells effectively target acute myeloid leukemia cells. Cancer Cell Int. 2023;23:297 pubmed publisher
Ferrarone J, Thomas J, Unni A, Zheng Y, Nagiec M, Gardner E, et al. LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase. bioRxiv. 2023;: pubmed publisher
Xiong R, Shao D, Do S, Chan W. Activation of Chaperone-Mediated Autophagy Inhibits the Aryl Hydrocarbon Receptor Function by Degrading This Receptor in Human Lung Epithelial Carcinoma A549 Cells. Int J Mol Sci. 2023;24: pubmed publisher
Zhang J, Keibler M, Dong W, Ghelfi J, Cordes T, Kanashova T, et al. Stable Isotope-Assisted Untargeted Metabolomics Identifies ALDH1A1-Driven Erythronate Accumulation in Lung Cancer Cells. Biomedicines. 2023;11: pubmed publisher
Poohadsuan J, O Doherty G, Owattanapanich W, Kungwankiattichai S, Rojanasakul Y, Issaragrisil S, et al. Cardiac glycoside ouabain efficiently targets leukemic stem cell apoptotic machinery independent of cell differentiation status. Cell Commun Signal. 2023;21:283 pubmed publisher
Liu L, Wei J, Chen C, Liang Q, Wang B, Wu W, et al. Electroporation-based Easi-CRISPR yields biallelic insertions of EGFP-HiBiT cassette in immortalized chicken oviduct epithelial cells. Poult Sci. 2023;102:103112 pubmed publisher
Batra J, Chi T, Huang M, Zhu D, Chen Z, Lee D, et al. Wearable Biosensor with Molecularly Imprinted Conductive Polymer Structure to Detect Lentivirus in Aerosol. Biosensors (Basel). 2023;13: pubmed publisher
McAloney C, Makkawi R, Budhathoki Y, Cannon M, Franz E, Gross A, et al. Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization. Cell Oncol (Dordr). 2023;: pubmed publisher
Boegholm N, Petriman N, Loureiro L xf3 pez M, Wang J, Vela M, Liu B, et al. The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport. EMBO J. 2023;42:e111807 pubmed publisher
Huang Y, Drakul A, Sidhu J, Rauwolf K, Kim J, Bornhauser B, et al. MSC.sensor: Capturing cancer cell interactions with stroma for functional profiling. SLAS Discov. 2023;: pubmed publisher
Soshnikova N, Simonov Y, Feoktistov A, Khamidullina A, Yastrebova M, Bayramova D, et al. New Approach for Studying of Isoforms and High-Homology Proteins in Mammalian Cells. Int J Mol Sci. 2023;24: pubmed publisher
Duan Y, Chen X, Zhu R, Jia Y, Huang X, Zhang M, et al. High-throughput functional dissection of noncoding SNPs with biased allelic enhancer activity for insulin resistance-relevant phenotypes. Am J Hum Genet. 2023;: pubmed publisher
Danisik N, Yilmaz K, Acar A. Identification of collateral sensitivity and evolutionary landscape of chemotherapy-induced drug resistance using cellular barcoding technology. Front Pharmacol. 2023;14:1178489 pubmed publisher
Sako H, Youssef M, Elisseeva O, Akimoto T, Suzuki K, Ushida T, et al. microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes. EMBO J. 2023;:e112469 pubmed publisher
Chakraborty P, Deb B, Arige V, Musthafa T, Malik S, Yule D, et al. Regulation of store-operated Ca2+ entry by IP3 receptors independent of their ability to release Ca2. elife. 2023;12: pubmed publisher
Pearsall S, Williamson S, Humphrey S, Hughes E, Morgan D, Garc xed a Marqu xe9 s F, et al. Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry. J Thorac Oncol. 2023;: pubmed publisher
Zhang L, Jiang C, Zhong Y, Sun K, Jing H, Song J, et al. STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2. Nat Cell Biol. 2023;: pubmed publisher
Beatriz M, Rodrigues R, Vila xe7 a R, Egas C, Pinheiro P, Daley G, et al. Extracellular vesicles improve GABAergic transmission in Huntington's disease iPSC-derived neurons. Theranostics. 2023;13:3707-3724 pubmed publisher
Bal xe7 x131 k Er xe7 in P, Aysan A, Sal x131 k N, Erciyas E. SIX1 Downregulation Suppresses Self-renewal Capacity and THY1 Expression in Hepatocellular Carcinoma and SIX1 Dominate the Survival in Liver Cancer. Turk J Gastroenterol. 2023;: pubmed publisher
Reynolds L, Hernandez G, MacGowan D, Popescu C, Nouel D, Cuesta S, et al. Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice. Nat Commun. 2023;14:4035 pubmed publisher
Kim I, Diamond M, Yuan S, Kemp S, Li Q, Lin J, et al. Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy. Res Sq. 2023;: pubmed publisher
Negoita F, Addinsall A, Hellberg K, Bringas C, Hafen P, Sermersheim T, et al. CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle. Mol Metab. 2023;75:101761 pubmed publisher
Wang Y, Wang R, Liu X, Liu M, Sun L, Pan X, et al. Chemotherapy-induced executioner caspase activation increases breast cancer malignancy through epigenetic de-repression of CDH12. Oncogenesis. 2023;12:34 pubmed publisher
Omrane M, Ben M barek K, Santinho A, Nguyen N, Nag S, Melia T, et al. LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy. Dev Cell. 2023;58:1266-1281.e7 pubmed publisher
Collora J, Ho Y. Integration site-dependent HIV-1 promoter activity shapes host chromatin conformation. Genome Res. 2023;33:891-906 pubmed publisher
Esposito R, Lanz xf3 s A, Uroda T, Ramnarayanan S, B xfc chi I, Polidori T, et al. Tumour mutations in long noncoding RNAs enhance cell fitness. Nat Commun. 2023;14:3342 pubmed publisher
Wei Y, Zhang L, Wang C, Li Z, Luo M, Xie G, et al. Anti-apoptotic protein BCL-XL as a therapeutic vulnerability in gastric cancer. Animal Model Exp Med. 2023;6:245-254 pubmed publisher
Pablo J, Cornett S, Wang L, Jo S, Br xfc nger T, Budnik N, et al. Scanning mutagenesis of the voltage-gated sodium channel NaV1.2 using base editing. Cell Rep. 2023;42:112563 pubmed publisher
Zhang F, Wu Z, Yu B, Ning Z, Lu Z, Li L, et al. ATP13A2 activates the pentose phosphate pathway to promote colorectal cancer growth though TFEB-PGD axis. Clin Transl Med. 2023;13:e1272 pubmed publisher
Park S, Khan M, Chiliveri S, Hu X, Irvin P, Leek M, et al. SARS-CoV-2 omicron variants harbor spike protein mutations responsible for their attenuated fusogenic phenotype. Commun Biol. 2023;6:556 pubmed publisher
Ogunmowo T, Jing H, Raychaudhuri S, Kusick G, Imoto Y, Li S, et al. Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis. Nat Commun. 2023;14:2888 pubmed publisher
Zhang J, Prasad C, Oo A, Qiu Z, Li N, Singh D, et al. The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity. Res Sq. 2023;: pubmed publisher
Taye N, Singh M, Baldock C, Hubmacher D. Secreted ADAMTS-like 2 promotes myoblast differentiation by potentiating WNT signaling. Matrix Biol. 2023;120:24-42 pubmed publisher
Mucha M, Skrzypiec A, Kolenchery J, Brambilla V, Patel S, Labrador Ramos A, et al. miR-483-5p offsets functional and behavioural effects of stress in male mice through synapse-targeted repression of Pgap2 in the basolateral amygdala. Nat Commun. 2023;14:2134 pubmed publisher
Sagar S, Faizan M, Chaudhary N, Singh V, Singh P, Gheware A, et al. Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells. Cell Death Dis. 2023;14:324 pubmed publisher
Zorea J, Motro Y, Mazor R, Carmi Y, Shulman Z, Mahajna J, et al. TRAF3 suppression encourages B cell recruitment and prolongs survival of microbiome-intact mice with ovarian cancer. J Exp Clin Cancer Res. 2023;42:107 pubmed publisher
Olivas T, Wu Y, Yu S, Luan L, Choi P, Guinn E, et al. ATG9 vesicles comprise the seed membrane of mammalian autophagosomes. J Cell Biol. 2023;222: pubmed publisher
da Fonseca Ferreira A, Wei J, Zhang L, Macon C, Degnan B, Jayaweera D, et al. HIV Promotes Atherosclerosis via Circulating Extracellular Vesicle MicroRNAs. Int J Mol Sci. 2023;24: pubmed publisher
Licht Murava A, Meadows S, Palaguachi F, Song S, Jackvony S, Bram Y, et al. Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines. Sci Adv. 2023;9:eade1282 pubmed publisher
Xiong X, Tasan I, Yang C, Zhang M, Hernandez Gonzalez G, Liu S, et al. Imaging Method Using CRISPR/dCas9 and Engineered gRNA Scaffolds Can Perturb Replication Timing at the HSPA1 Locus. ACS Synth Biol. 2023;12:1424-1436 pubmed publisher
M xf6 ller A, Jauch Speer S, Gandhi S, Vogl T, Roth J, Fehler O. The roles of toll-like receptor 4, CD33, CD68, CD69, or CD147/EMMPRIN for monocyte activation by the DAMP S100A8/S100A9. Front Immunol. 2023;14:1110185 pubmed publisher
Hermansen J, Yin Y, Urban A, Myklebust C, Karlsen L, Melvold K, et al. A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine. Cell Death Discov. 2023;9:125 pubmed publisher
Saunders J, Sikder K, Phillips E, Ishwar A, Mothy D, Margulies K, et al. Med25 Limits Master Regulators That Govern Adipogenesis. Int J Mol Sci. 2023;24: pubmed publisher
Xing Y, Dong R, Lee L, Rengarajan S, Riggi N, Boulay G, et al. DisP-seq reveals the genome-wide functional organization of DNA-associated disordered proteins. Nat Biotechnol. 2023;: pubmed publisher
Li J, Wan F, Zhang J, Zheng S, Yang Y, Hong Z, et al. Targeting SMYD2 inhibits prostate cancer cell growth by regulating c-Myc signaling. Mol Carcinog. 2023;62:940-950 pubmed publisher
Boudra R, Patenall B, King S, Wang D, Best S, Ko J, et al. PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma. bioRxiv. 2023;: pubmed publisher
Pacheco Fiallos B, Vorl xe4 nder M, Riabov Bassat D, Fin L, O Reilly F, Ayala F, et al. mRNA recognition and packaging by the human transcription-export complex. Nature. 2023;616:828-835 pubmed publisher
Rivera Mej xed as P, Narbona P xe9 rez x, Hasberg L, Kroczek L, Bahat A, Lawo S, et al. The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage. Cell Rep. 2023;42:112332 pubmed publisher
Gengyi Z, Yuanjian H, Zhang S, Ko K, Kim B, Zhang J, et al. CDH1 loss promotes diffuse-type gastric cancer tumorigenesis via epigenetic reprogramming and immune evasion. bioRxiv. 2023;: pubmed publisher
Delgado J, Wallace Shepard L, Lamson S, Liu S, Shoemaker C. The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy. bioRxiv. 2023;: pubmed publisher
Mart Nez Terroba E, de Miguel F, Li V, Robles Oteiza C, Politi K, Zamudio J, et al. Overexpressed Malat1 Drives Metastasis through Inflammatory Reprogramming of Lung Adenocarcinoma Microenvironment. bioRxiv. 2023;: pubmed publisher
Zhang H, Kelly K, Lee J, Echeverria D, Cooper D, Panwala R, et al. Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo. bioRxiv. 2023;: pubmed publisher
Ho T, Lee M, Goh H, Ng G, Lee J, Kannan S, et al. Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Nat Commun. 2023;14:1726 pubmed publisher
Dalseno D, Anderton H, Kueh A, Herold M, Silke J, Strasser A, et al. Deletion of Gpatch2 does not alter Tnf expression in mice. Cell Death Dis. 2023;14:214 pubmed publisher
Ngo A, Puschnik A. Genome-Scale Analysis of Cellular Restriction Factors That Inhibit Transgene Expression from Adeno-Associated Virus Vectors. J Virol. 2023;97:e0194822 pubmed publisher
Sarabia S xe1 nchez M, Moreno Londo xf1 o A, Casta xf1 eda Patl xe1 n M, Alvarado Ortiz E, Mart xed nez Morales J, Robles Flores M. Non-canonical Wnt/Ca2+ signaling is essential to promote self-renewal and proliferation in colon cancer stem cells. Front Oncol. 2023;13:1121787 pubmed publisher
Li W, Liu S, Wang C, Cui L, Zhao X, Liu W, et al. DNMT3A low-expression is correlated to poor prognosis in childhood B-ALL and confers resistance to daunorubicin on leukemic cells. BMC Cancer. 2023;23:255 pubmed publisher
Lewis M, Terr xe9 B, Knobel P, Cheng T, Lu H, Attolini C, et al. GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program. Cell Death Dis. 2023;14:201 pubmed publisher
Gilhaus K, Cepok C, Kamm D, Surmann B, Nedvetsky P, Emich J, et al. Activation of Hippo Pathway Damages Slit Diaphragm by Deprivation of Ajuba Proteins. J Am Soc Nephrol. 2023;34:1039-1055 pubmed publisher
Vornholz L, Isay S, Kurgyis Z, Strobl D, Loll P, Mosa M, et al. Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Sci Adv. 2023;9:eadd8564 pubmed publisher
Phan Q, Solis N, Cravener M, Swidergall M, Lin J, Huang M, et al. Candida albicans stimulates the formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection. bioRxiv. 2023;: pubmed publisher
Dilley J, Seetharam A, Ding X, Bello M, Shutter J, Burr D, et al. CAMKK2 is upregulated in primary human osteoarthritis and its inhibition protects against chondrocyte apoptosis. Osteoarthritis Cartilage. 2023;31:908-918 pubmed publisher
Valiullina A, Zmievskaya E, Ganeeva I, Zhuravleva M, Garanina E, Rizvanov A, et al. Evaluation of CAR-T Cells' Cytotoxicity against Modified Solid Tumor Cell Lines. Biomedicines. 2023;11: pubmed publisher
Zhang S, Kim K, Huang Y, Kim D, Kim B, Ko K, et al. CRACD loss promotes small cell lung cancer tumorigenesis via EZH2-mediated immune evasion. bioRxiv. 2023;: pubmed publisher
Lin H, Sandkuhler S, Dunlea C, King D, Johnson G. BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1. bioRxiv. 2023;: pubmed publisher
Su S, Xue Y, Lee S, Zhang Y, Fan J, De S, et al. A dual-activity topoisomerase complex promotes both transcriptional activation and repression in response to starvation. Nucleic Acids Res. 2023;51:2415-2433 pubmed publisher
Maloshenok L, Abushinova G, Kazachkina N, Bogdanov A, Zherdeva V. Tet-Regulated Expression and Optical Clearing for In Vivo Visualization of Genetically Encoded Chimeric dCas9/Fluorescent Protein Probes. Materials (Basel). 2023;16: pubmed publisher
Ozkan N, Yigit B, Degirmenci B, Qureshi M, Yapici G, Kamac x131 oglu A, et al. Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis. J Cell Sci. 2023;136: pubmed publisher
Lin K, Yang Y, Cao Y, Liang J, Qian J, Wang X, et al. Combining single-cell transcriptomics and CellTagging to identify differentiation trajectories of human adipose-derived mesenchymal stem cells. Stem Cell Res Ther. 2023;14:14 pubmed publisher
Chung Y, Bisht M, Thuma J, Tu L. Single-chromosome dynamics reveals locus-dependent dynamics and chromosome territory orientation. J Cell Sci. 2023;136: pubmed publisher
Kanie T, Ng R, Abbott K, Pongs O, Jackson P. Myristoylated Neuronal Calcium Sensor-1 captures the ciliary vesicle at distal appendages. bioRxiv. 2023;: pubmed publisher
Guna A, Page K, Replogle J, Esantsi T, Wang M, Weissman J, et al. A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens. bioRxiv. 2023;: pubmed publisher
Kanie T, Love J, Fisher S, Gustavsson A, Jackson P. A hierarchical pathway for assembly of the distal appendages that organize primary cilia. bioRxiv. 2023;: pubmed publisher
Choi K, Ko C, An S, Cho S, Rowland D, Kim J, et al. Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT. Mol Metab. 2023;69:101679 pubmed publisher
Najm F, DeWeirdt P, Moore M, Bevill S, El Farran C, Macias K, et al. Chromatin complex dependencies reveal targeting opportunities in leukemia. Nat Commun. 2023;14:448 pubmed publisher
Gallagher E, Holzbaur E. The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy. Cell Rep. 2023;42:112037 pubmed publisher
Jeon E, Choi D, Choi S, Won J, Jo Y, Kim H, et al. Enhancing adoptive T-cell therapy with fucoidan-based IL-2 delivery microcapsules. Bioeng Transl Med. 2023;8:e10362 pubmed publisher
Chulpanova D, Pukhalskaia T, Gilazieva Z, Filina Y, Mansurova M, Rizvanov A, et al. Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model. Curr Issues Mol Biol. 2023;45:571-592 pubmed publisher
Katsioudi G, Dreos R, Arpa E, Gaspari S, Liechti A, Sato M, et al. A conditional Smg6 mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway. Sci Adv. 2023;9:eade2828 pubmed publisher
Xu J, Yuan A, Su R, Yang Q, Fan X, Zhang J. Trophoblast-specific knockdown of CSPG4 expression causes pregnancy complications with poor placentation in mice. Reprod Biol. 2023;23:100731 pubmed publisher
Fankhaenel M, Hashemi F, Mourao L, Lucas E, Hosawi M, Skipp P, et al. Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis. Nat Commun. 2023;14:151 pubmed publisher
De Bakshi D, Chen Y, Wuerzberger Davis S, Ma M, Waters B, Li L, et al. Ectopic CH60 mediates HAPLN1-induced cell survival signaling in multiple myeloma. Life Sci Alliance. 2023;6: pubmed publisher
Das M, Chang Y, Anderson R, Saunders R, Zhang N, Tomberlin C, et al. Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs. Proc Natl Acad Sci U S A. 2023;120:e2215071120 pubmed publisher
Ratnayeke N, Baris Y, Chung M, Yeeles J, Meyer T. CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis. Mol Cell. 2023;83:26-42.e13 pubmed publisher
Yamasaki M, Kanai Y, Wakamura Y, Kotaki T, Minami S, Nouda R, et al. Characterization of Sialic Acid-Independent Simian Rotavirus Mutants in Viral Infection and Pathogenesis. J Virol. 2023;97:e0139722 pubmed publisher
Salvi A, Hardy L, Heath K, Watry S, Pergande M, Cologna S, et al. PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome. Neoplasia. 2023;36:100866 pubmed publisher
Juras P, Racioppi L, Mukherjee D, Artham S, Gao X, Akullian D Agostino L, et al. Increased CaMKK2 Expression Is an Adaptive Response That Maintains the Fitness of Tumor-Infiltrating Natural Killer Cells. Cancer Immunol Res. 2023;11:109-122 pubmed publisher
Sloat S, Hoppins S. A dominant negative mitofusin causes mitochondrial perinuclear clusters because of aberrant tethering. Life Sci Alliance. 2023;6: pubmed publisher
Anderson K, Whitehead B, Petersen E, Kemme M, Wedster A, Hochgeschwender U, et al. Behavioral Context Improves Optogenetic Stimulation of Transplanted Dopaminergic Cells in Unilateral 6-OHDA Rats. Behav Brain Res. 2022;:114279 pubmed publisher
Huo J, Dijokaite Guraliuc A, Liu C, Zhou D, Ginn H, Das R, et al. A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75. Cell Rep. 2022;:111903 pubmed publisher
Kamimoto K, Adil M, Jindal K, Hoffmann C, Kong W, Yang X, et al. Gene regulatory network reconfiguration in direct lineage reprogramming. Stem Cell Reports. 2022;: pubmed publisher
Kim M, Park J, Kim S, Han D, Shin B, Sch xf6 ler H, et al. Generation of Induced Pluripotent Stem Cells from Lymphoblastoid Cell Lines by Electroporation of Episomal Vectors. Int J Stem Cells. 2022;: pubmed publisher
Peng Q, Huang Z, Sun K, Liu Y, Yoon C, Harrison R, et al. Engineering inducible biomolecular assemblies for genome imaging and manipulation in living cells. Nat Commun. 2022;13:7933 pubmed publisher
Kriachkov V, Ormsby A, Kusnadi E, McWilliam H, Mintern J, Amarasinghe S, et al. Arginine-rich C9ORF72 ALS proteins stall ribosomes in a manner distinct from a canonical ribosome-associated quality control substrate. J Biol Chem. 2022;299:102774 pubmed publisher
Peng N, Kang H, Feng Y, Minikes A, Jiang X. Autophagy inhibition signals through senescence to promote tumor suppression. Autophagy. 2022;:1-17 pubmed publisher
Luanpitpong S, Janan M, Yosudjai J, Poohadsuan J, Chanvorachote P, Issaragrisil S. Bcl-2 Family Members Bcl-xL and Bax Cooperatively Contribute to Bortezomib Resistance in Mantle Cell Lymphoma. Int J Mol Sci. 2022;23: pubmed publisher
K xf6 hler B, Dubovik S, H xf6 rterer E, Wilk U, St xf6 ckl J, Tekarslan Sahin H, et al. Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification. Cancers (Basel). 2022;14: pubmed publisher
Duan Y, Wang J, Cai J, Kelley N, He Y. The leucine-rich repeat (LRR) domain of NLRP3 is required for NLRP3 inflammasome activation in macrophages. J Biol Chem. 2022;298:102717 pubmed publisher
Darawshi O, Muz B, Naamat S, Praveen B, Mahameed M, Goldberg K, et al. An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma. Cell Death Dis. 2022;13:969 pubmed publisher
Angulo M, Bertalovitz A, Argenziano M, Yang J, Patel A, Zesiewicz T, et al. Frataxin deficiency alters gene expression in Friedreich ataxia derived IPSC-neurons and cardiomyocytes. Mol Genet Genomic Med. 2022;:e2093 pubmed publisher
Feng X, Yang G, Zhang L, Tao S, Shim J, Chen L, et al. TRIM59 guards ER proteostasis and prevents Bortezomib-mediated colorectal cancer (CRC) cells' killing. Invest New Drugs. 2022;40:1244-1253 pubmed publisher
Morente L xf3 pez M, Mato Basalo R, Lucio Gallego S, Silva Fern xe1 ndez L, Gonz xe1 lez Rodr xed guez A, De Toro F, et al. Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA. Cell Mol Life Sci. 2022;79:557 pubmed publisher
Faizan M, Chaudhuri R, Sagar S, Albogami S, Chaudhary N, Azmi I, et al. NSP4 and ORF9b of SARS-CoV-2 Induce Pro-Inflammatory Mitochondrial DNA Release in Inner Membrane-Derived Vesicles. Cells. 2022;11: pubmed publisher
Ruibal P, Derksen I, van Wolfswinkel M, Voogd L, Franken K, El Hebieshy A, et al. Thermal-exchange HLA-E multimers reveal specificity in HLA-E and NKG2A/CD94 complex interactions. Immunology. 2022;: pubmed publisher
Weier A, Homrich M, Ebbinghaus S, Juda P, Mikov xe1 E, Hauschild R, et al. Multiple centrosomes enhance migration and immune cell effector functions of mature dendritic cells. J Cell Biol. 2022;221: pubmed publisher
Bao C, Duan J, Xie Y, Liu Y, Li P, Li J, et al. A novel oncogenic enhancer of estrogen receptor-positive breast cancer. Mol Ther Nucleic Acids. 2022;29:836-851 pubmed publisher
Tao X, Wu X, Zhou P, Yu X, Zhao C, Peng X, et al. UBE2T promotes glioblastoma malignancy through ubiquitination-mediated degradation of RPL6. Cancer Sci. 2022;: pubmed publisher
Luanpitpong S, Rodboon N, Samart P, Janan M, Klaihmon P, Lorthongpanich C, et al. Inhibition of O-GlcNAcase Inhibits Hematopoietic and Leukemic Stem Cell Self-Renewal and Drives Dendritic Cell Differentiation via STAT3/5 Signaling. Stem Cells. 2022;40:1078-1093 pubmed publisher
Russell S, Lim F, Peters P, Wardell S, Whitaker R, Chang C, et al. Development and Characterization of a Luciferase Labeled, Syngeneic Murine Model of Ovarian Cancer. Cancers (Basel). 2022;14: pubmed publisher
Kim Y, Potashnikova D, Gisina A, Kholodenko I, Kopylov A, Tikhonova O, et al. TRIM28 Is a Novel Regulator of CD133 Expression Associated with Cancer Stem Cell Phenotype. Int J Mol Sci. 2022;23: pubmed publisher
Olou A, Ambrose J, Jack J, Walsh M, Ruckert M, Eades A, et al. SHP2 regulates adipose maintenance and adipocyte-pancreatic cancer cell crosstalk via PDHA1. J Cell Commun Signal. 2022;: pubmed publisher
DeWeirdt P, McGee A, Zheng F, Nwolah I, Hegde M, Doench J. Accounting for small variations in the tracrRNA sequence improves sgRNA activity predictions for CRISPR screening. Nat Commun. 2022;13:5255 pubmed publisher
Choi S, Flamand M, Liu B, Zhu H, Hu M, Wang M, et al. RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs. Cell Rep. 2022;40:111293 pubmed publisher
Li S, Patel J, Yang J, Crabtree A, Rubenstein B, Lund Andersen P, et al. Defining the HIV Capsid Binding Site of Nucleoporin 153. mSphere. 2022;7:e0031022 pubmed publisher
Sanidas I, Lee H, Rumde P, Boulay G, Morris R, Golczer G, et al. Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression. Mol Cell. 2022;82:3333-3349.e9 pubmed publisher
Ratto E, Chowdhury S, Siefert N, Schneider M, Wittmann M, Helm D, et al. Direct control of lysosomal catabolic activity by mTORC1 through regulation of V-ATPase assembly. Nat Commun. 2022;13:4848 pubmed publisher
Li J, Lin J, Lin J, Farris M, Robbins L, Andrada L, et al. Dolutegravir Inhibits Proliferation and Motility of BT-20 Tumor Cells Through Inhibition of Human Endogenous Retrovirus Type K. Cureus. 2022;14:e26525 pubmed publisher
Zhao P, Xu Y, Fan X, Li L, Li X, Arase H, et al. Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice. MAbs. 2022;14:2107971 pubmed publisher
Brown M, Abdollahi B, Wilkins O, Lu H, Chakraborty P, Ognjenovic N, et al. Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer. Sci Adv. 2022;8:eabj8002 pubmed publisher
Hiatt J, Sandborg H, Garrison S, Arnold H, Liao S, Norton J, et al. Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing. Clin Cancer Res. 2022;28:4551-4564 pubmed publisher
Gusho E, Laimins L. Human papillomaviruses sensitize cells to DNA damage induced apoptosis by targeting the innate immune sensor cGAS. PLoS Pathog. 2022;18:e1010725 pubmed publisher
Acklin S, Sadhukhan R, Du W, Patra M, Cholia R, Xia F. Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation. Neurooncol Adv. 2022;4:vdac101 pubmed publisher
Oktelik F, Yilmaz V, Gelmez M, Akdeniz N, Pamukcu C, Sutlu T, et al. Decline of humoral immune responses after natural SARS-CoV-2 infection can be efficiently reversed by vaccination. Can J Microbiol. 2022;68:543-550 pubmed publisher
Schmieder S, Tatituri R, Anderson M, Kelly K, Lencer W. Structural basis for acyl chain control over glycosphingolipid sorting and vesicular trafficking. Cell Rep. 2022;40:111063 pubmed publisher
Jiang Y, Ji J. Progerin-Induced Impairment in Wound Healing and Proliferation in Vascular Endothelial Cells. Front Aging. 2022;3:844885 pubmed publisher
Narita S, Unno K, Kato K, Okuno Y, Sato Y, Tsumura Y, et al. Direct reprogramming of adult adipose-derived regenerative cells toward cardiomyocytes using six transcriptional factors. iScience. 2022;25:104651 pubmed publisher
Kim P, Park J, Lee D, Mizuno S, Shinohara M, Hong C, et al. Mast4 determines the cell fate of MSCs for bone and cartilage development. Nat Commun. 2022;13:3960 pubmed publisher
Chu H, Peterson C, Chamling X, Berlinicke C, Zack D, Jun A, et al. Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production. Invest Ophthalmol Vis Sci. 2022;63:1 pubmed publisher
Ragab N, Bauer J, Uhmann A, Marx A, Hahn H, Simon Keller K. Tumor suppressive functions of WNT5A in rhabdomyosarcoma. Int J Oncol. 2022;61: pubmed publisher
Schmitt D, Curtis S, Lyons A, Zhang J, Chen M, He C, et al. Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter. Nat Commun. 2022;13:3856 pubmed publisher
Quan M, Oh Y, Cho S, Kim J, Moon H. Polo-Like Kinase 1 Regulates Chromosomal Instability and Paclitaxel Resistance in Breast Cancer Cells. J Breast Cancer. 2022;25:178-192 pubmed publisher
Hutcheson R, Hayes M, Sugden B. Optimal LentiCRISPR-Based System for Sequential CRISPR/Cas9 Screens. ACS Synth Biol. 2022;: pubmed publisher
Im N, Guillaumet Adkins A, Wal M, Rogers A, Frede J, Havig C, et al. Regulatory programs of B-cell activation and germinal center reaction allow B-ALL escape from CD19 CAR T-cell therapy. Cancer Immunol Res. 2022;: pubmed publisher
Khan T, Ginsburg D, Emmer B. The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes. J Lipid Res. 2022;:100248 pubmed publisher
Chen P, Wang W, Wong S, Li J, Wu Q, Zhang S, et al. RUNDC3A regulates SNAP25-mediated chemotherapy resistance by binding AKT in gastric neuroendocrine carcinoma (GNEC). Cell Death Discov. 2022;8:296 pubmed publisher
Zhang P, Amarasinghe H, Whalley J, Tay C, Fang H, Migliorini G, et al. Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance. Genome Biol. 2022;23:136 pubmed publisher
Cortés Kaplan S, Kurdieh R, Hasim M, Kaczmarek S, Taha Z, Maznyi G, et al. A New Functional Screening Platform Identifies Colistin Sulfate as an Enhancer of Natural Killer Cell Cytotoxicity. Cancers (Basel). 2022;14: pubmed publisher
Liu H, Lin J, Zhou W, Moses R, Dai Z, Kossenkov A, et al. KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer. Cancer Immunol Res. 2022;:OF1-OF11 pubmed publisher
Velimirovic M, Zanetti L, Shen M, Fife J, Lin L, Cha M, et al. Peptide fusion improves prime editing efficiency. Nat Commun. 2022;13:3512 pubmed publisher
Zhao P, Xu Y, Jiang L, Fan X, Ku Z, Li L, et al. LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Mol Neurodegener. 2022;17:44 pubmed publisher
Zhou R, Han B, Nowak R, Lu Y, Heller E, Xia C, et al. Proteomic and functional analyses of the periodic membrane skeleton in neurons. Nat Commun. 2022;13:3196 pubmed publisher
Cao L, Luo Y, Guo X, Liu S, Li S, Li J, et al. SAFA facilitates chromatin opening of immune genes through interacting with anti-viral host RNAs. PLoS Pathog. 2022;18:e1010599 pubmed publisher
Kim K, Shin D, Lee G, Bae H. Loss of SP-A in the Lung Exacerbates Pulmonary Fibrosis. Int J Mol Sci. 2022;23: pubmed publisher
Thege F, Cardle I, Gruber C, Siemann M, Cong S, Wittmann K, et al. Acquired chemoresistance drives spatial heterogeneity, chemoprotection and collective migration in pancreatic tumor spheroids. PLoS ONE. 2022;17:e0267882 pubmed publisher
Gubat J, Selvaraju K, Sjöstrand L, Kumar Singh D, Turkina M, Schmierer B, et al. Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action. Front Oncol. 2022;12:852980 pubmed publisher
Reticker Flynn N, Zhang W, Belk J, Basto P, Escalante N, Pilarowski G, et al. Lymph node colonization induces tumor-immune tolerance to promote distant metastasis. Cell. 2022;185:1924-1942.e23 pubmed publisher
Kalejaiye T, Bhattacharya R, Burt M, Travieso T, Okafor A, Mou X, et al. SARS-CoV-2 Employ BSG/CD147 and ACE2 Receptors to Directly Infect Human Induced Pluripotent Stem Cell-Derived Kidney Podocytes. Front Cell Dev Biol. 2022;10:855340 pubmed publisher
Li R, Klingbeil O, Monducci D, Young M, Rodríguez D, Bayyat Z, et al. Comparative optimization of combinatorial CRISPR screens. Nat Commun. 2022;13:2469 pubmed publisher
Shi X, Reinstadler B, Shah H, To T, Byrne K, Summer L, et al. Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS. Nat Commun. 2022;13:2483 pubmed publisher
Saito Y, Matsuda S, Ohnishi N, Endo K, Ashitani S, Ohishi M, et al. Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer. Commun Biol. 2022;5:403 pubmed publisher
Nouruzi S, Ganguli D, Tabrizian N, Kobelev M, Sivak O, Namekawa T, et al. ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer. Nat Commun. 2022;13:2282 pubmed publisher
Tse L, Meganck R, Araba K, Yount B, Shaffer K, Hou Y, et al. Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection. Proc Natl Acad Sci U S A. 2022;119:e2118126119 pubmed publisher
Huang D, Camacho C, Martire S, Nagari A, Setlem R, Gong X, et al. Oncohistone Mutations Occur at Functional Sites of Regulatory ADP-Ribosylation. Cancer Res. 2022;82:2361-2377 pubmed publisher
Ma H, de Zwaan E, Guo Y, Cejas P, Thiru P, van de Bunt M, et al. The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes. Cell Stem Cell. 2022;29:795-809.e11 pubmed publisher
Greenough M, Lane D, Balez R, Anastacio H, Zeng Z, Ganio K, et al. Selective ferroptosis vulnerability due to familial Alzheimer's disease presenilin mutations. Cell Death Differ. 2022;: pubmed publisher
Cao K, Riley J, Heilig R, Montes Gómez A, Vringer E, Berthenet K, et al. Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage. Dev Cell. 2022;57:1211-1225.e6 pubmed publisher
Winkler L, Jimenez M, Zimmer J, Williams A, Simon M, Dimitrova N. Functional elements of the cis-regulatory lincRNA-p21. Cell Rep. 2022;39:110687 pubmed publisher
Caruso L, Guo R, Keith K, Madzo J, Maestri D, Boyle S, et al. The nuclear lamina binds the EBV genome during latency and regulates viral gene expression. PLoS Pathog. 2022;18:e1010400 pubmed publisher
Hasim M, Marotel M, Hodgins J, Vulpis E, Makinson O, Asif S, et al. When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer. Sci Adv. 2022;8:eabj3286 pubmed publisher
Xu D, He Y, Xiao B, Si Y, Shi J, Liu X, et al. A Novel Sushi-IL15-PD1 CAR-NK92 Cell Line With Enhanced and PD-L1 Targeted Cytotoxicity Against Pancreatic Cancer Cells. Front Oncol. 2022;12:726985 pubmed publisher
Zhao P, Anami Y, Gao P, Fan X, Li L, Tsuchikama K, et al. Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model. MAbs. 2022;14:2057269 pubmed publisher
Piao X, Meng D, Zhang X, Song Q, Lv H, Jia Y. Dual-gRNA approach with limited off-target effect corrects C9ORF72 repeat expansion in vivo. Sci Rep. 2022;12:5672 pubmed publisher
Yu S, Sui Y, Wang J, Li Y, Li H, Cao Y, et al. Crystal structure and cellular functions of uPAR dimer. Nat Commun. 2022;13:1665 pubmed publisher
Skylar Scott M, Huang J, Lu A, Ng A, Duenki T, Liu S, et al. Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissues. Nat Biomed Eng. 2022;6:449-462 pubmed publisher
Allen V, Coulombe J, Zhao H, Kreps L, Cook D, Pryce B, et al. VIVA1: a more invasive subclone of MDA-MB-134VI invasive lobular carcinoma cells with increased metastatic potential in xenograft models. Br J Cancer. 2022;: pubmed publisher
Böck D, Rothgangl T, Villiger L, Schmidheini L, Matsushita M, Mathis N, et al. In vivo prime editing of a metabolic liver disease in mice. Sci Transl Med. 2022;14:eabl9238 pubmed publisher
Zhou P, Song G, He W, Beutler N, Tse L, Martinez D, et al. Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease. bioRxiv. 2022;: pubmed publisher
Townley B, Soll J, Mosammaparast N. Immunoaffinity Purification of Epitope-Tagged DNA Repair Complexes from Human Cells. Methods Mol Biol. 2022;2444:29-41 pubmed publisher
Sangree A, Griffith A, Szegletes Z, Roy P, DeWeirdt P, Hegde M, et al. Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2. Nat Commun. 2022;13:1318 pubmed publisher
Bonilla Pons S, Nakagawa S, Bahima E, Fernández Blanco Á, Pesaresi M, D Antin J, et al. Müller glia fused with adult stem cells undergo neural differentiation in human retinal models. EBioMedicine. 2022;77:103914 pubmed publisher
Krajka V, Vulinović F, Genova M, Tanzer K, Jijumon A, Bodakuntla S, et al. H-ABC- and dystonia-causing TUBB4A mutations show distinct pathogenic effects. Sci Adv. 2022;8:eabj9229 pubmed publisher
Tian H, Zhao H, Qu B, Chu X, Xin X, Zhang Q, et al. TRIM24 promotes colorectal cancer cell progression via the Wnt/β-catenin signaling pathway activation. Am J Transl Res. 2022;14:831-848 pubmed
Xu W, Zhang W, Cui L, Shi L, Zhu B, Lyu T, et al. Novel mutation of SIK1 gene causing a mild form of pediatric epilepsy in a Chinese patient. Metab Brain Dis. 2022;37:1207-1219 pubmed publisher
Fanfone D, Wu Z, Mammi J, Berthenet K, Neves D, Weber K, et al. Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness. elife. 2022;11: pubmed publisher
Murray C, Brady J, Han M, Cai H, Tsai M, Pierce S, et al. LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer. Nat Commun. 2022;13:1090 pubmed publisher
Vaidyanathan S, Salmi T, Sathiqu R, McConville M, Cox A, Brown K. YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth. Dev Cell. 2022;57:719-731.e8 pubmed publisher
Nuth M, Benakanakere M, Ricciardi R. Discovery of a potent cytotoxic agent that promotes G2/M phase cell cycle arrest and apoptosis in a malignant human pharyngeal squamous carcinoma cell line. Int J Oncol. 2022;60: pubmed publisher
Roblek M, Bicher J, van Gogh M, György A, Seeböck R, Szulc B, et al. The Solute Carrier MFSD1 Decreases the Activation Status of β1 Integrin and Thus Tumor Metastasis. Front Oncol. 2022;12:777634 pubmed publisher
Zhang T, Zhao J, Liu T, Cheng W, Wang Y, Ding S, et al. A novel mechanism for NLRP3 inflammasome activation. Metabol Open. 2022;13:100166 pubmed publisher
Marcheva B, Weidemann B, Taguchi A, Perelis M, Ramsey K, Newman M, et al. P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure. elife. 2022;11: pubmed publisher
Boyero L, Martin Padron J, Fárez Vidal M, Rodriguez M, Andrades Á, Peinado P, et al. PKP1 and MYC create a feedforward loop linking transcription and translation in squamous cell lung cancer. Cell Oncol (Dordr). 2022;45:323-332 pubmed publisher
Shi X, Yang J, Liu M, Zhang Y, Zhou Z, Luo W, et al. Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-β Signaling Axis in Pancreatic Cancer. Gastroenterology. 2022;162:2004-2017.e2 pubmed publisher
Ruan Y, Hu J, Che Y, Liu Y, Luo Z, Cheng J, et al. CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response. Cell Death Dis. 2022;13:156 pubmed publisher
Pang J, Feng X, Liang Q, Zheng X, Duan Y, Zhang X, et al. Ferritin-Nanocaged ATP Traverses the Blood-Testis Barrier and Enhances Sperm Motility in an Asthenozoospermia Model. ACS Nano. 2022;16:4175-4185 pubmed publisher
Deng Z, Yao J, Xiao N, Han Y, Wu X, Ci C, et al. DNA methyltransferase 1 (DNMT1) suppresses mitophagy and aggravates heart failure via the microRNA-152-3p/ETS1/RhoH axis. Lab Invest. 2022;: pubmed publisher
Gerber P, Duncan L, Greenwood E, Marelli S, Naamati A, Teixeira Silva A, et al. A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection. PLoS Pathog. 2022;18:e1010265 pubmed publisher
Dutto I, Gerhards J, Herrera A, Souckova O, Skopova V, Smak J, et al. Pathway-specific effects of ADSL deficiency on neurodevelopment. elife. 2022;11: pubmed publisher
Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, et al. A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection. Sci Transl Med. 2022;14:eabi9215 pubmed publisher
Ito Y, Takasawa A, Takasawa K, Murakami T, Akimoto T, Kyuno D, et al. Aberrant expression of claudin-6 contributes to malignant potentials and drug resistance of cervical adenocarcinoma. Cancer Sci. 2022;113:1519-1530 pubmed publisher
Steiner S, Seleznik G, Reding T, Stopic M, Lenggenhager D, Ten Buren E, et al. De novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancer. Oncogene. 2022;41:1507-1517 pubmed publisher
Date Y, Matsuura A, Itakura E. Disruption of actin dynamics induces autophagy of the eukaryotic chaperonin TRiC/CCT. Cell Death Discov. 2022;8:37 pubmed publisher
Hagenlocher C, Siebert R, Taschke B, Wieske S, Hausser A, Rehm M. ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic β cells. Cell Death Discov. 2022;8:34 pubmed publisher
Maslennikova A, Kruglova N, Kalinichenko S, Komkov D, Shepelev M, Golubev D, et al. Engineering T-Cell Resistance to HIV-1 Infection via Knock-In of Peptides from the Heptad Repeat 2 Domain of gp41. MBio. 2022;:e0358921 pubmed publisher
Martin M, Sandhu P, Kumar R, Buchkovich N. The Immune-Specific E3 Ubiquitin Ligase MARCH1 Is Upregulated during Human Cytomegalovirus Infection to Regulate Iron Levels. J Virol. 2022;96:e0180621 pubmed publisher
Luke C, Markovina S, Good M, Wight I, Thomas B, Linneman J, et al. Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins. Commun Biol. 2022;5:47 pubmed publisher
Salvi A, Young A, Huntsman A, Pergande M, Korkmaz M, Rathnayake R, et al. PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer. Cell Death Dis. 2022;13:45 pubmed publisher
Park S, Irvin P, Hu Z, Khan M, Hu X, Zeng Q, et al. Targeting the Fusion Process of SARS-CoV-2 Infection by Small Molecule Inhibitors. MBio. 2022;:e0323821 pubmed publisher
Saliakoura M, Sebastiano M, Nikdima I, Pozzato C, Konstantinidou G. Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy. J Exp Clin Cancer Res. 2022;41:16 pubmed publisher
Du L, Liu W, Aldana Masangkay G, Pozhitkov A, Pichiorri F, Chen Y, et al. SUMOylation inhibition enhances dexamethasone sensitivity in multiple myeloma. J Exp Clin Cancer Res. 2022;41:8 pubmed publisher
Lu Y, Chan Y, Tan H, Zhang C, Guo W, Xu Y, et al. Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma. J Exp Clin Cancer Res. 2022;41:3 pubmed publisher
Dellomo A, Abbotts R, Eberly C, Karbowski M, Baer M, Kingsbury T, et al. PARP1 PARylates and stabilizes STAT5 in FLT3-ITD acute myeloid leukemia and other STAT5-activated cancers. Transl Oncol. 2022;15:101283 pubmed publisher
Quan Y, Shan X, Hu M, Jin P, Ma J, Fan J, et al. YAP inhibition promotes endothelial cell differentiation from pluripotent stem cell through EC master transcription factor FLI1. J Mol Cell Cardiol. 2022;163:81-96 pubmed publisher
Shaimardanova A, Chulpanova D, Solovyeva V, Aimaletdinov A, Rizvanov A. Functionality of a bicistronic construction containing HEXA and HEXB genes encoding β-hexosaminidase A for cell-mediated therapy of GM2 gangliosidoses. Neural Regen Res. 2022;17:122-129 pubmed publisher
Chaki S, Alkanfari I, Roy S, Amponnawarat A, Hui Y, Oskeritzian C, et al. Inhibition of Orai Channel Function Regulates Mas-Related G Protein-Coupled Receptor-Mediated Responses in Mast Cells. Front Immunol. 2021;12:803335 pubmed publisher
Rappaport J, Entezari A, Caspi A, Caksa S, Jhaveri A, Stanek T, et al. A β-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2021;: pubmed publisher
Gutierrez C, Al Khafaji A, Brenner E, Johnson K, Gohil S, Lin Z, et al. Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment. Nat Cancer. 2021;2:758-772 pubmed publisher
Hu L, Chen L, Xiao Z, Zheng X, Chen Y, Xian N, et al. Ablation of T cell-associated PD-1H enhances functionality and promotes adoptive immunotherapy. JCI Insight. 2021;: pubmed publisher
Reint G, Li Z, Labun K, Keskitalo S, Soppa I, Mamia K, et al. Rapid genome editing by CRISPR-Cas9-POLD3 fusion. elife. 2021;10: pubmed publisher
Zimmer M, Kibe A, Rand U, Pekarek L, Ye L, Buck S, et al. The short isoform of the host antiviral protein ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting. Nat Commun. 2021;12:7193 pubmed publisher
Troitskaya O, Novak D, Nushtaeva A, Savinkova M, Varlamov M, Ermakov M, et al. EGFR Transgene Stimulates Spontaneous Formation of MCF7 Breast Cancer Cells Spheroids with Partly Loss of HER3 Receptor. Int J Mol Sci. 2021;22: pubmed publisher
Campden R, Warren A, Greene C, Chiriboga J, Arnold C, Aggarwal D, et al. Extracellular cathepsin Z signals through the α5 integrin and augments NLRP3 inflammasome activation. J Biol Chem. 2021;:101459 pubmed publisher
Tremblay M, Green M, Goldstein B, Aldridge A, Rosenfeld J, Streff H, et al. Mutations of the histone linker H1-4 in neurodevelopmental disorders and functional characterization of neurons expressing C-terminus frameshift mutant H1.4. Hum Mol Genet. 2021;: pubmed publisher
Yang D, Wu X, Wang W, Zhou Y, Wang Z. Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy. Adv Sci (Weinh). 2021;:e2102568 pubmed publisher
Ageely E, Chilamkurthy R, Jana S, Abdullahu L, O Reilly D, Jensik P, et al. Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles. Nat Commun. 2021;12:6591 pubmed publisher
Farooq U, Notani D. Optimized protocol to create deletion in adherent cell lines using CRISPR/Cas9 system. STAR Protoc. 2021;2:100857 pubmed publisher
Shaw A, Tóth B, Kiraly R, Arianti R, Csomós I, Poliska S, et al. Irisin Stimulates the Release of CXCL1 From Differentiating Human Subcutaneous and Deep-Neck Derived Adipocytes via Upregulation of NFκB Pathway. Front Cell Dev Biol. 2021;9:737872 pubmed publisher
Rahman F, Johnson J, Zhang J, He J, Pestonjamasp K, Cherqui S, et al. DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis. Autophagy. 2021;:1-19 pubmed publisher
Shao M, Zhang Q, Truong A, Shan B, Vishvanath L, Li L, et al. ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes. Genes Dev. 2021;35:1461-1474 pubmed publisher
Sengupta D, Zeng L, Li Y, Hausmann S, Ghosh D, Yuan G, et al. NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis. Mol Cell. 2021;81:4481-4492.e9 pubmed publisher
Liu W, Hsu A, Wang Y, Lin T, Sun H, Pachter J, et al. Mitofusin-2 regulates leukocyte adhesion and β2 integrin activation. J Leukoc Biol. 2021;: pubmed publisher
Francis C, Kushner E. Capturing membrane trafficking events during 3D angiogenic development in vitro. Microcirculation. 2021;:e12726 pubmed publisher
Yu W, Ma H, Li J, Ge J, Wang P, Zhou Y, et al. DDX52 knockdown inhibits the growth of prostate cancer cells by regulating c-Myc signaling. Cancer Cell Int. 2021;21:430 pubmed publisher
Quinn S, Huang L, Kerkvliet J, Swanson J, Smith S, Hoppe A, et al. The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy. Nat Commun. 2021;12:4838 pubmed publisher
Nuebel E, Morgan J, Fogarty S, Winter J, Lettlova S, Berg J, et al. The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder. EMBO Rep. 2021;:e51991 pubmed publisher
Reilly S, Gosai S, Gutierrez A, Mackay Smith A, Ulirsch J, Kanai M, et al. Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR-FlowFISH. Nat Genet. 2021;53:1166-1176 pubmed publisher
Challa S, Khulpateea B, Nandu T, Camacho C, Ryu K, Chen H, et al. Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers. Cell. 2021;: pubmed publisher
Liu M, Klement J, Langan C, van Riggelen J, Liu K. Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells. Cell Immunol. 2021;366:104397 pubmed publisher
Garcia Garcia S, Rodrigo Faus M, Fonseca N, Manzano S, Gyorffy B, Ocana A, et al. HGK promotes metastatic dissemination in prostate cancer. Sci Rep. 2021;11:12287 pubmed publisher
Chen S, Chen Y, Wen Y, Cai W, Zhu P, Yuan W, et al. miR-590-5p targets RMND5A and promotes migration in pancreatic adenocarcinoma cell lines. Oncol Lett. 2021;22:532 pubmed publisher
Wei T, Choi S, Buehler D, Lee D, Ward Shaw E, Anderson R, et al. Role of IQGAP1 in Papillomavirus-Associated Head and Neck Tumorigenesis. Cancers (Basel). 2021;13: pubmed publisher
Nazitto R, Amon L, Mast F, Aitchison J, Aderem A, Johnson J, et al. ILF3 Is a Negative Transcriptional Regulator of Innate Immune Responses and Myeloid Dendritic Cell Maturation. J Immunol. 2021;: pubmed publisher
Ganga A, Kennedy M, Oguchi M, Gray S, Oliver K, Knight T, et al. Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway. Curr Biol. 2021;31:2895-2905.e7 pubmed publisher
Cai H, Liu X, Zhang F, Han Q, Liu Z, Xue W, et al. G3BP1 Inhibition Alleviates Intracellular Nucleic Acid-Induced Autoimmune Responses. J Immunol. 2021;206:2453-2467 pubmed publisher
Miwatani Minter B, Róna G. Laser Micro-Irradiation to Study DNA Recruitment During S Phase. J Vis Exp. 2021;: pubmed publisher
Le Voyer T, Neehus A, Yang R, Ogishi M, Rosain J, Alroqi F, et al. Inherited deficiency of stress granule ZNFX1 in patients with monocytosis and mycobacterial disease. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Liu Y, Zou L, Wang P, Zhou J, Yuan C, Wang J. Construction of differential expression plasmids of NGF to detect its influence on PC12 cell neuronal differentiation. Exp Ther Med. 2021;21:363 pubmed publisher
Samart P, Luanpitpong S, Rojanasakul Y, Issaragrisil S. O-GlcNAcylation homeostasis controlled by calcium influx channels regulates multiple myeloma dissemination. J Exp Clin Cancer Res. 2021;40:100 pubmed publisher
Klement J, Poschel D, Lu C, Merting A, Yang D, Redd P, et al. Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression. Cancers (Basel). 2021;13: pubmed publisher
Rybakova Y, Gonzalez J, Bogorad R, Chauhan V, Dong Y, Whittaker C, et al. Identification of a long non-coding RNA regulator of liver carcinoma cell survival. Cell Death Dis. 2021;12:178 pubmed publisher
Zhou X, Xiao F, Sugimoto H, Li B, McAndrews K, Kalluri R. Acute kidney injury instigates malignant renal cell carcinoma via CXCR2 in mice with inactivated Trp53 and Pten in proximal tubular kidney epithelial cells. Cancer Res. 2021;: pubmed publisher
Addison J, Voronkova M, Fugett J, Lin C, Linville N, Trinh B, et al. Functional hierarchy and cooperation of EMT master transcription factors in breast cancer metastasis. Mol Cancer Res. 2021;: pubmed publisher
Trayssac M, Clarke C, Stith J, Snider J, Newen N, Gault C, et al. Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides. Cell Death Dis. 2021;12:27 pubmed publisher
Ledet R, Ruff S, Wang Y, Nayak S, Schneider J, Ueberheide B, et al. Identification of PIM1 substrates reveals a role for NDRG1 phosphorylation in prostate cancer cellular migration and invasion. Commun Biol. 2021;4:36 pubmed publisher
Smith M, Querido E, Chartrand P, Sfeir A. Quantitative Imaging of MS2-Tagged hTR in Cajal Bodies: Photobleaching and Photoactivation. STAR Protoc. 2020;1:100112 pubmed publisher
Dong X, Yang Y, Zou Z, Zhao Y, Ci B, Zhong L, et al. Sorting nexin 5 mediates virus-induced autophagy and immunity. Nature. 2021;589:456-461 pubmed publisher
Wei H, Beeson G, Ye Z, Zhang J, Yao H, Damon B, et al. Activation of Wnt/β-catenin signalling and HIF1α stabilisation alters pluripotency and differentiation/proliferation properties of human-induced pluripotent stem cells. Biol Cell. 2020;: pubmed publisher
Duan Y, Zhang L, Angosto Bazarra D, Pelegrin P, Nunez G, He Y. RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly. Cell Rep. 2020;33:108405 pubmed publisher
Kimura Y, Iwanaga E, Iwanaga K, Endo S, Inoue Y, Tokunaga K, et al. A regulatory element in the 3'-untranslated region of CEBPA is associated with myeloid/NK/T-cell leukemia. Eur J Haematol. 2021;106:327-339 pubmed publisher
Avanzini M, Mura M, Percivalle E, Bastaroli F, Croce S, Valsecchi C, et al. Human mesenchymal stromal cells do not express ACE2 and TMPRSS2 and are not permissive to SARS-CoV-2 infection. Stem Cells Transl Med. 2021;10:636-642 pubmed publisher
Saliakoura M, Rossi Sebastiano M, Pozzato C, Heidel F, Schnöder T, Savic Prince S, et al. PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nat Cell Biol. 2020;22:1382-1395 pubmed publisher
Olivo Pimentel V, Yaromina A, Marcus D, Dubois L, Lambin P. A novel co-culture assay to assess anti-tumor CD8+ T cell cytotoxicity via luminescence and multicolor flow cytometry. J Immunol Methods. 2020;487:112899 pubmed publisher
Yang J, Lee S, Kwon Y, Ma L, Kim J. Tumor suppressive function of Matrin 3 in the basal-like breast cancer. Biol Res. 2020;53:42 pubmed publisher
Koessinger A, Koessinger D, Stevenson K, Cloix C, Mitchell L, Nixon C, et al. Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts. Sci Rep. 2020;10:15361 pubmed publisher
Zhan H, Bhattacharya S, Cai H, Iglesias P, Huang C, Devreotes P. An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells. Dev Cell. 2020;54:608-623.e5 pubmed publisher
Wang S, Liu Y, Crisman L, Wan C, Miller J, Yu H, et al. Genetic evidence for an inhibitory role of tomosyn in insulin-stimulated GLUT4 exocytosis. Traffic. 2020;21:636-646 pubmed publisher
Du L, Fakih M, Rosen S, Chen Y. SUMOylation of E2F1 Regulates Expression of EZH2. Cancer Res. 2020;80:4212-4223 pubmed publisher
Barbuti P, Santos B, Dording C, Cruciani G, Massart F, Hummel A, et al. Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson's disease patient carrying the heterozygous p.A30P mutation in SNCA. Stem Cell Res. 2020;48:101951 pubmed publisher
Barter M, Cheung K, Falk J, Panagiotopoulos A, Cosimini C, O Brien S, et al. Dynamic chromatin accessibility landscape changes following interleukin-1 stimulation. Epigenetics. 2021;16:106-119 pubmed publisher
Garbutt T, Zhou Y, Keepers B, Liu J, Qian L. An Optimized Protocol for Human Direct Cardiac Reprogramming. STAR Protoc. 2020;1: pubmed publisher
Foltz L, Palacios Moreno J, Mayfield M, Kinch S, Dillon J, Syrenne J, et al. PAG1 directs SRC-family kinase intracellular localization to mediate receptor tyrosine kinase-induced differentiation. Mol Biol Cell. 2020;31:2269-2282 pubmed publisher
Berkhout B, Herrera Carrillo E. Design and Evaluation of AgoshRNAs with 3'-Terminal HDV Ribozymes to Enhance the Silencing Activity. Methods Mol Biol. 2021;2167:225-252 pubmed publisher
Cambria E, Arlt M, Wandel S, Krupkova O, Hitzl W, Passini F, et al. TRPV4 Inhibition and CRISPR-Cas9 Knockout Reduce Inflammation Induced by Hyperphysiological Stretching in Human Annulus Fibrosus Cells. Cells. 2020;9: pubmed publisher
Whitlock N, Trostel S, Wilkinson S, Terrigino N, Hennigan S, Lake R, et al. MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity. Oncogene. 2020;: pubmed publisher
Zhao G, Kim E, Jiang J, Bhoot C, Charles K, Baek J, et al. CCN1/Cyr61 is required in osteoblasts for responsiveness to the anabolic activity of PTH. J Bone Miner Res. 2020;: pubmed publisher
Perrigue P, Rakoczy M, Pawlicka K, Belter A, Giel Pietraszuk M, Naskret Barciszewska M, et al. Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts. Cancers (Basel). 2020;12: pubmed publisher
Demirkol Canlı S, Seza E, Sheraj I, Gomceli I, Turhan N, Carberry S, et al. Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway. Carcinogenesis. 2020;: pubmed publisher
Brownmiller T, Juric J, Ivey A, Harvey B, Westemeier E, Winters M, et al. Y Chromosome LncRNA are involved in Radiation Response of Male Non-Small Cell Lung Cancer Cells. Cancer Res. 2020;: pubmed publisher
Vergara Mendoza M, Gomez Quiroz L, Miranda Labra R, Fuentes Romero L, Romero Rodríguez D, González Ruiz J, et al. Regulation of Cas9 by viral proteins Tat and Rev for HIV-1 inactivation. Antiviral Res. 2020;180:104856 pubmed publisher
Yang Y, Huang X, Ma G, Cui J, Matsubara J, Kazlauskas A, et al. PDGFRβ plays an essential role in patient vitreous-stimulated contraction of retinal pigment epithelial cells from epiretinal membranes. Exp Eye Res. 2020;197:108116 pubmed publisher
Kang Y, Falzone A, Liu M, González Sánchez P, Choi B, Coloff J, et al. PHGDH supports liver ceramide synthesis and sustains lipid homeostasis. Cancer Metab. 2020;8:6 pubmed publisher
DiScala M, Najor M, Yung T, Morgan D, Abukhdeir A, Cobleigh M. Loss of STAT6 leads to anchorage-independent growth and trastuzumab resistance in HER2+ breast cancer cells. PLoS ONE. 2020;15:e0234146 pubmed publisher
Gregory J, Hoelzli E, Abdelaal R, Braine C, Cuevas M, Halpern M, et al. Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models. Cells. 2020;9: pubmed publisher
Ibrahim M, Lu C, Klement J, Redd P, Yang D, Smith A, et al. Expression profiles and function of IL6 in polymorphonuclear myeloid-derived suppressor cells. Cancer Immunol Immunother. 2020;: pubmed publisher
Delavallée L, Mathiah N, Cabon L, Mazeraud A, Brunelle Navas M, Lerner L, et al. Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus. Mol Metab. 2020;40:101027 pubmed publisher
Kim K, Yoon J, Shin B, Röpke A, Han D, Scholer H. Generation of a human iPSC line (MPIi006-A) from a patient with Pelizaeus-Merzbacher disease. Stem Cell Res. 2020;46:101839 pubmed publisher
Stöhr D, Schmid J, Beigl T, Mack A, Maichl D, Cao K, et al. Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids. Cell Death Differ. 2020;: pubmed publisher
Yatsuka Y, Kishita Y, Formosa L, Shimura M, Nozaki F, Fujii T, et al. A homozygous variant in NDUFA8 is associated with developmental delay, microcephaly, and epilepsy due to mitochondrial complex I deficiency. Clin Genet. 2020;98:155-165 pubmed publisher
He C, Jaffar Ali D, Xu H, Kumaravel S, Si K, Li Y, et al. Epithelial cell -derived microvesicles: A safe delivery platform of CRISPR/Cas9 conferring synergistic anti-tumor effect with sorafenib. Exp Cell Res. 2020;392:112040 pubmed publisher
Oizel K, Tait Mulder J, Fernandez de Cossio Diaz J, Pietzke M, Brunton H, Lilla S, et al. Formate induces a metabolic switch in nucleotide and energy metabolism. Cell Death Dis. 2020;11:310 pubmed publisher
Morikawa K, Furuhashi K, de Sena Tomás C, Garcia Garcia A, Bekdash R, Klein A, et al. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Nat Commun. 2020;11:2141 pubmed publisher
Elsarraj H, Hong Y, Limback D, Zhao R, Berger J, Bishop S, et al. BCL9/STAT3 regulation of transcriptional enhancer networks promote DCIS progression. NPJ Breast Cancer. 2020;6:12 pubmed publisher
Fassmannová D, Sedlák F, Sedlacek J, Spicka I, Grantz Sasková K. Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma. Cancers (Basel). 2020;12: pubmed publisher
Martello A, Lauriola A, Mellis D, Parish E, Dawson J, Imrie L, et al. Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy. EMBO Rep. 2020;21:e48192 pubmed publisher
Ding B, Yuan F, Damle P, Litovchick L, Drapkin R, Grossman S. CtBP determines ovarian cancer cell fate through repression of death receptors. Cell Death Dis. 2020;11:286 pubmed publisher
Hock D, Reljic B, Ang C, Muellner Wong L, Mountford H, Compton A, et al. HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV. Mol Cell Proteomics. 2020;19:1145-1160 pubmed publisher
Nallanthighal S, Rada M, Heiserman J, Cha J, Sage J, Zhou B, et al. Inhibition of collagen XI alpha 1-induced fatty acid oxidation triggers apoptotic cell death in cisplatin-resistant ovarian cancer. Cell Death Dis. 2020;11:258 pubmed publisher
Murugaiah V, Varghese P, Saleh S, Tsolaki A, Alrokayan S, Khan H, et al. Complement-Independent Modulation of Influenza A Virus Infection by Factor H. Front Immunol. 2020;11:355 pubmed publisher
Ward N, Kang Y, Falzone A, Boyle T, DeNicola G. Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function. J Exp Med. 2020;217: pubmed publisher
Akimov Y, Bulanova D, Timonen S, Wennerberg K, Aittokallio T. Improved detection of differentially represented DNA barcodes for high-throughput clonal phenomics. Mol Syst Biol. 2020;16:e9195 pubmed publisher
Kanasugi J, Hanamura I, Ota A, Karnan S, Lam V, Mizuno S, et al. Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells. Cancer Sci. 2020;111:1663-1675 pubmed publisher
Ray J, de Boer C, Fulco C, Lareau C, Kanai M, Ulirsch J, et al. Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features. Nat Commun. 2020;11:1237 pubmed publisher
Demaret T, Courtoy G, Ravau J, Van Der Smissen P, Najimi M, Sokal E. Accurate and live peroxisome biogenesis evaluation achieved by lentiviral expression of a green fluorescent protein fused to a peroxisome targeting signal 1. Histochem Cell Biol. 2020;153:295-306 pubmed publisher
De Fusco A, Cerullo M, Marte A, Michetti C, Romei A, Castroflorio E, et al. Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis. Neurobiol Dis. 2020;139:104822 pubmed publisher
Zhang J, Yu W, Wang X, Hu B, Wu D, Shi G. KLF16 Affects the MYC Signature and Tumor Growth in Prostate Cancer. Onco Targets Ther. 2020;13:1303-1310 pubmed publisher
Wang W, Lin D, Jarman E, Polacheck W, Baker B. Functional angiogenesis requires microenvironmental cues balancing endothelial cell migration and proliferation. Lab Chip. 2020;20:1153-1166 pubmed publisher
Farrants H, Tarnawski M, Müller T, Otsuka S, Hiblot J, Koch B, et al. Chemogenetic Control of Nanobodies. Nat Methods. 2020;17:279-282 pubmed publisher
Lee D, Park S, Huh Y, Jung Kim M, Seo H, Ha T, et al. Iridoids of Valeriana fauriei contribute to alleviating hepatic steatosis in obese mice by lipophagy. Biomed Pharmacother. 2020;125:109950 pubmed publisher
Kong W, Biddy B, Kamimoto K, Amrute J, Butka E, Morris S. CellTagging: combinatorial indexing to simultaneously map lineage and identity at single-cell resolution. Nat Protoc. 2020;15:750-772 pubmed publisher
DeWeirdt P, Sangree A, Hanna R, Sanson K, Hegde M, Strand C, et al. Genetic screens in isogenic mammalian cell lines without single cell cloning. Nat Commun. 2020;11:752 pubmed publisher
Bunda S, Heir P, Li A, Mamatjan Y, Zadeh G, Aldape K. c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein. Mol Cancer Res. 2020;18:774-786 pubmed publisher
Marin Navarro A, Pronk R, van der Geest A, Oliynyk G, Nordgren A, Arsenian Henriksson M, et al. p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids. Cell Death Dis. 2020;11:52 pubmed publisher
Hiranniramol K, Chen Y, Liu W, Wang X. Generalizable sgRNA design for improved CRISPR/Cas9 editing efficiency. Bioinformatics. 2020;36:2684-2689 pubmed publisher
Ahi Y, Yimer D, Shi G, Majdoul S, Rahman K, Rein A, et al. IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag. MBio. 2020;11: pubmed publisher
Johnstone C, Pattison A, Harrison P, Powell D, Lock P, Ernst M, et al. FGF13 promotes metastasis of triple-negative breast cancer. Int J Cancer. 2020;147:230-243 pubmed publisher
Zhang S, Gao W, Tang J, Zhang H, Zhou Y, Liu J, et al. The Roles of GSK-3β in Regulation of Retinoid Signaling and Sorafenib Treatment Response in Hepatocellular Carcinoma. Theranostics. 2020;10:1230-1244 pubmed publisher
Yamazaki H, Shirakawa K, Matsumoto T, Kazuma Y, Matsui H, Horisawa Y, et al. APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression. PLoS ONE. 2020;15:e0223463 pubmed publisher
Bodakuntla S, Janke C, Magiera M. Knocking Out Multiple Genes in Cultured Primary Neurons to Study Tubulin Posttranslational Modifications. Methods Mol Biol. 2020;2101:327-351 pubmed publisher
Wang C. A Sensitive and Quantitative mKeima Assay for Mitophagy via FACS. Curr Protoc Cell Biol. 2020;86:e99 pubmed publisher
Carbonetti G, Wilpshaar T, Kroonen J, Studholme K, Converso C, d Oelsnitz S, et al. FABP5 coordinates lipid signaling that promotes prostate cancer metastasis. Sci Rep. 2019;9:18944 pubmed publisher
Dudek A, Zabaleta N, Zinn E, Pillay S, Zengel J, Porter C, et al. GPR108 Is a Highly Conserved AAV Entry Factor. Mol Ther. 2019;: pubmed publisher
Luong P, Li Q, Chen P, Wrighton P, Chang D, Dwyer S, et al. A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization. Mol Biol Cell. 2019;:mbcE19070375 pubmed publisher
Yang L, Wang Y, Li S, Yao R, Luan P, Wu H, et al. Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems. Mol Cell. 2019;76:981-997.e7 pubmed publisher
Wang S, Crisman L, Miller J, Datta I, Gulbranson D, Tian Y, et al. Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis. J Biol Chem. 2019;294:19988-19996 pubmed publisher
Wang L, Shen E, Luo L, Rabe H, Wang Q, Yin J, et al. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2019;29:1848-1861.e6 pubmed publisher
Garland K, Sevimli S, Kilchrist K, Duvall C, Cook R, Wilson J. Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles. Cell Mol Bioeng. 2019;12:429-442 pubmed publisher
Ehsanipour A, Nguyen T, Aboufadel T, Sathialingam M, Cox P, Xiao W, et al. Injectable, Hyaluronic Acid-Based Scaffolds with Macroporous Architecture for Gene Delivery. Cell Mol Bioeng. 2019;12:399-413 pubmed publisher
Helassa N, Nugues C, Rajamanoharan D, Burgoyne R, Haynes L. A centrosome-localized calcium signal is essential for mammalian cell mitosis. FASEB J. 2019;33:14602-14610 pubmed publisher
Lee J, Ghonime M, Cassady K. STING Restricts oHSV Replication and Spread in Resistant MPNSTs but Is Dispensable for Basal IFN-Stimulated Gene Upregulation. Mol Ther Oncolytics. 2019;15:91-100 pubmed publisher
Shohat S, Shifman S. Genes essential for embryonic stem cells are associated with neurodevelopmental disorders. Genome Res. 2019;29:1910-1918 pubmed publisher
Dong H, Godlewska M, Wade M. A rapid assay of human thyroid peroxidase activity. Toxicol In Vitro. 2020;62:104662 pubmed publisher
Gul N, Karlsson J, Tängemo C, Linsefors S, Tuyizere S, Perkins R, et al. The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway. Sci Rep. 2019;9:14667 pubmed publisher
Allen M, Zhou W, Thangaraj J, Kyriakakis P, Wu Y, Huang Z, et al. An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics. ACS Synth Biol. 2019;8:2359-2371 pubmed publisher
Gomes A, Ilter D, Low V, Rosenzweig A, Shen Z, Schild T, et al. Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Cancer Cell. 2019;36:402-417.e13 pubmed publisher
Ko T, Sharma R, Li S. Genome-wide screening identifies novel genes implicated in cellular sensitivity to BRAFV600E expression. Oncogene. 2019;: pubmed publisher
Roczniak Ferguson A, Ferguson S. Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis. Life Sci Alliance. 2019;2: pubmed publisher
Babosova O, Kapralova K, Raskova Kafkova L, Korinek V, Divoky V, Prchal J, et al. Iron chelation and 2-oxoglutarate-dependent dioxygenase inhibition suppress mantle cell lymphoma's cyclin D1. J Cell Mol Med. 2019;23:7785-7795 pubmed publisher
Shi Y, Yu J, Zhang Y, Zhao B, Li Y, Ye Y, et al. RhTyrRS (Y341A), a novel human tyrosyl-tRNA synthetase mutant, stimulates thrombopoiesis through activation of the VEGF-R II/NF-κB pathway. Biochem Pharmacol. 2019;169:113634 pubmed publisher
Bassaganyas L, Popa S, Horlbeck M, Puri C, Stewart S, Campelo F, et al. New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells. J Cell Biol. 2019;218:3861-3879 pubmed publisher
Yagensky O, Kohansal Nodehi M, Gunaseelan S, Rabe T, Zafar S, Zerr I, et al. Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. elife. 2019;8: pubmed publisher
Hennessy E, van Solingen C, Scacalossi K, Ouimet M, Afonso M, Prins J, et al. The long noncoding RNA CHROME regulates cholesterol homeostasis in primate. Nat Metab. 2019;1:98-110 pubmed publisher
Shim J, Lee B, Park H. Visualization of Single mRNAs in Live Neurons. Methods Mol Biol. 2019;2038:47-61 pubmed publisher
Vera M, Tutucci E, Singer R. Imaging Single mRNA Molecules in Mammalian Cells Using an Optimized MS2-MCP System. Methods Mol Biol. 2019;2038:3-20 pubmed publisher
Park M, Wong M, Arauzo Bravo M, Lee H, Nam D, Park S, et al. Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model. PLoS ONE. 2019;14:e0221085 pubmed publisher
Antao N, Marcet Ortega M, Cifani P, Kentsis A, Foley E. A Cancer-Associated Missense Mutation in PP2A-Aα Increases Centrosome Clustering during Mitosis. iScience. 2019;19:74-82 pubmed publisher
Kim D, Camacho C, Nagari A, Malladi V, Challa S, Kraus W. Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21. Mol Cell. 2019;: pubmed publisher
Liu G, Wang Y, Zheng W, Cheng H, Zhou R. P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice. Int J Biol Sci. 2019;15:1383-1395 pubmed publisher
Caines R, Cochrane A, Kelaini S, Vilà González M, Yang C, Eleftheriadou M, et al. The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy. J Cell Sci. 2019;132: pubmed publisher
Zhang H, Huang J, Liu Y, Ren H, Xie J, Chen N. Endoplasmic reticulum stress and proteasome pathway involvement in human podocyte injury with a truncated COL4A3 mutation. Chin Med J (Engl). 2019;132:1823-1832 pubmed publisher
Guo H, Shen S, Li Y, Bi R, Zhang N, Zheng W, et al. Adenovirus oncoprotein E4orf6 triggers Cullin5 neddylation to activate the CLR5 E3 ligase for p53 degradation. Biochem Biophys Res Commun. 2019;516:1242-1247 pubmed publisher
Garanina E, Martynova E, Davidyuk Y, Kabwe E, Ivanov K, Titova A, et al. Cytokine Storm Combined with Humoral Immune Response Defect in Fatal Hemorrhagic Fever with Renal Syndrome Case, Tatarstan, Russia. Viruses. 2019;11: pubmed publisher
Wang F, Chang C, Li R, Zhang Z, Jiang H, Zeng N, et al. Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells. Toxicology. 2019;: pubmed publisher
Liu X, Wei L, Dong Q, Liu L, Zhang M, Xie Z, et al. A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. Aging (Albany NY). 2019;11:4011-4031 pubmed publisher
Turturro S, Najor M, Yung T, Portt L, Malarkey C, Abukhdeir A, et al. Somatic loss of PIK3R1 may sensitize breast cancer to inhibitors of the MAPK pathway. Breast Cancer Res Treat. 2019;: pubmed publisher
Wu L, Xia M, Duan Y, Zhang L, Jiang H, Hu X, et al. Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans. Cell Death Dis. 2019;10:468 pubmed publisher
Won H, Huang J, Opland C, Hartl C, Geschwind D. Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility. Nat Commun. 2019;10:2396 pubmed publisher
Tsutsumiuchi M, Hoshino H, Kogami A, Tsutsumiuchi T, Yokoyama O, Akama T, et al. Preferential expression of sialyl 6'-sulfo N-acetyllactosamine-capped O-glycans on high endothelial venules in human peripheral lymph nodes. Lab Invest. 2019;: pubmed publisher
Freije A, Sanz Gómez N, Gandarillas A. Genetic Modification of Human Primary Keratinocytes by Lentiviral Vectors. Methods Mol Biol. 2019;: pubmed publisher
Kang Y, Torrente L, Falzone A, Elkins C, Liu M, Asara J, et al. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. elife. 2019;8: pubmed publisher
Zhao X, Ren Y, Lawlor M, Shah B, Park P, Lwin T, et al. BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models. Cancer Cell. 2019;35:752-766.e9 pubmed publisher
Malik N, Yan H, Moshkovich N, Palangat M, Yang H, Sanchez V, et al. The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription. Nat Commun. 2019;10:2071 pubmed publisher
Yan C, Brunson D, Tang Q, Do D, Iftimia N, Moore J, et al. Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish. Cell. 2019;: pubmed publisher
Saito Y, Li L, Coyaud E, Luna A, Sander C, Raught B, et al. LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer. Nature. 2019;569:275-279 pubmed publisher
Lee D, Ahn J, Jang Y, Ha T, Jung C. Oleic acid-induced defective autolysosome shows impaired lipid degradation. Biochem Biophys Res Commun. 2019;513:553-559 pubmed publisher
Schulman J, Szczesniak L, Bunker E, Nelson H, Roe M, Wagner L, et al. Bok regulates mitochondrial fusion and morphology. Cell Death Differ. 2019;: pubmed publisher
Valverde D, Yu S, Boggavarapu V, Kumar N, Lees J, Walz T, et al. ATG2 transports lipids to promote autophagosome biogenesis. J Cell Biol. 2019;218:1787-1798 pubmed publisher
Chryplewicz A, Tienda S, Nahotko D, Peters P, Lengyel E, Eckert M. Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6. Sci Rep. 2019;9:5195 pubmed publisher
Stringer B, Day B, D Souza R, Jamieson P, Ensbey K, Bruce Z, et al. A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma. Sci Rep. 2019;9:4902 pubmed publisher
Li H, Petersen S, García Mariscal A, Brakebusch C. Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation. Cancer Res. 2019;79:2167-2181 pubmed publisher
Chua M, Yildirim E, Tan J, Chua Y, Low S, Ding S, et al. Assessment of different strategies for scalable production and proliferation of human myoblasts. Cell Prolif. 2019;52:e12602 pubmed publisher
Ko T, Li S. Genome-wide screening identifies novel genes and biological processes implicated in cisplatin resistance. FASEB J. 2019;33:7143-7154 pubmed publisher
Vershkov D, Fainstein N, Suissa S, Golan Lev T, Ben Hur T, Benvenisty N. FMR1 Reactivating Treatments in Fragile X iPSC-Derived Neural Progenitors In Vitro and In Vivo. Cell Rep. 2019;26:2531-2539.e4 pubmed publisher
Schatoff E, Paz Zafra M, Dow L. Base editing the mammalian genome. Methods. 2019;: pubmed publisher
Zotova A, Pichugin A, Atemasova A, Knyazhanskaya E, Lopatukhina E, Mitkin N, et al. Isolation of gene-edited cells via knock-in of short glycophosphatidylinositol-anchored epitope tags. Sci Rep. 2019;9:3132 pubmed publisher
Cui J, Zhou Z, Yang H, Jiao F, Li N, Gao Y, et al. MST1 Suppresses Pancreatic Cancer Progression via ROS-Induced Pyroptosis. Mol Cancer Res. 2019;17:1316-1325 pubmed publisher
Yuan N, Cai C, Wu M, Zhu Q, Su H, Li M, et al. Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology. Front Pharmacol. 2019;10:16 pubmed publisher
Deng Y, Bi R, Guo H, Yang J, Du Y, Wang C, et al. Andrographolide Enhances TRAIL-Induced Apoptosis via p53-Mediated Death Receptors Up-Regulation and Suppression of the NF-кB Pathway in Bladder Cancer Cells. Int J Biol Sci. 2019;15:688-700 pubmed publisher
Tedja R, Roberts C, Alvero A, Cardenas C, Yang Hartwich Y, Spadinger S, et al. Protein kinase Cα-mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it. J Biol Chem. 2019;294:5082-5093 pubmed publisher
Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, et al. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019;176:1113-1127.e16 pubmed publisher
Gao X, Rodríguez T, Sontheimer E. Adapting dCas9-APEX2 for subnuclear proteomic profiling. Methods Enzymol. 2019;616:365-383 pubmed publisher
D Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, et al. The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. Mol Cell. 2019;73:775-787.e10 pubmed publisher
Boyd N, Walker K, Ayokanmbi A, Gordon E, Whetsel J, Smith C, et al. Chromodomain Helicase DNA-Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma Angiogenesis. Stem Cells. 2019;37:453-462 pubmed publisher
Jachimowicz R, Beleggia F, Isensee J, Velpula B, Goergens J, Bustos M, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019;176:505-519.e22 pubmed publisher
Chen M, Lo Y, Chen X, Williams C, Donnelly J, Criss Z, et al. Growth Factor-Independent 1 Is a Tumor Suppressor Gene in Colorectal Cancer. Mol Cancer Res. 2019;17:697-708 pubmed publisher
Liu Y, Qin S, Chen T, Lei M, Dhar S, Ho J, et al. Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun. 2019;10:36 pubmed publisher
Zhu T, Tian D, Zhang L, Xu X, Xia K, Hu Z, et al. Novel mutations in mevalonate kinase cause disseminated superficial actinic porokeratosis. Br J Dermatol. 2018;: pubmed publisher
Zheng T, Ma G, Tang M, Li Z, Xu R. IL-8 Secreted from M2 Macrophages Promoted Prostate Tumorigenesis via STAT3/MALAT1 Pathway. Int J Mol Sci. 2018;20: pubmed publisher
Fritzell K, Xu L, Otrocka M, Andréasson C, Ohman M. Sensitive ADAR editing reporter in cancer cells enables high-throughput screening of small molecule libraries. Nucleic Acids Res. 2019;47:e22 pubmed publisher
LI Y, Du L, Wang J, Vega R, Lee T, Miao Y, et al. Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme. Cell Chem Biol. 2019;26:278-288.e6 pubmed publisher
Tiemann K, Garri C, Lee S, Malihi P, Park M, Alvarez R, et al. Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis. Oncogene. 2019;38:3003-3018 pubmed publisher
Sanson K, Hanna R, Hegde M, Donovan K, Strand C, Sullender M, et al. Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities. Nat Commun. 2018;9:5416 pubmed publisher
Mon E, Wei F, Ahmad R, Yamamoto T, Moroishi T, Tomizawa K. Regulation of mitochondrial iron homeostasis by sideroflexin 2. J Physiol Sci. 2019;69:359-373 pubmed publisher
Hong X, Li S, Li W, Xie M, Wei Z, Guo H, et al. Disruption of protein neddylation with MLN4924 attenuates paclitaxel-induced apoptosis and microtubule polymerization in ovarian cancer cells. Biochem Biophys Res Commun. 2018;: pubmed publisher
Adelmann C, Wang T, Sabatini D, Lander E. Genome-Wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines. Methods Mol Biol. 2019;1907:125-136 pubmed publisher
Makhoul C, Gosavi P, Duffield R, Delbridge B, Williamson N, Gleeson P. Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Mol Biol Cell. 2019;30:370-386 pubmed publisher
Wang R, Tan J, Chen T, Han H, Tian R, Tan Y, et al. ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion. J Cell Biol. 2019;218:267-284 pubmed publisher
Kowalczyk Quintas C, Chevalley D, Willen L, Jandus C, Vigolo M, Schneider P. Inhibition of Membrane-Bound BAFF by the Anti-BAFF Antibody Belimumab. Front Immunol. 2018;9:2698 pubmed publisher
Biddy B, Kong W, Kamimoto K, Guo C, Waye S, Sun T, et al. Single-cell mapping of lineage and identity in direct reprogramming. Nature. 2018;564:219-224 pubmed publisher
Tandon N, Thakkar K, LaGory E, Liu Y, Giaccia A. Generation of Stable Expression Mammalian Cell Lines Using Lentivirus. Bio Protoc. 2018;8: pubmed publisher
Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio A, Sérandour A, et al. Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation. Nucleic Acids Res. 2018;46:11214-11228 pubmed publisher
Nejati Moharrami N, Bjørkøy Tande E, Ryan L, Espevik T, Boyartchuk V. RORα controls inflammatory state of human macrophages. PLoS ONE. 2018;13:e0207374 pubmed publisher
Roberto G, Vieira G, Delsin L, Silva M, Hakime R, Engel E, et al. MiR-708-5p is inversely associated with EWS/FLI1 Ewing sarcoma but does not represent a prognostic predictor. Cancer Genet. 2019;230:21-27 pubmed publisher
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, et al. PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis. Apoptosis. 2019;24:135-144 pubmed publisher
Dias M, Fonseca C, Zeidler J, Albuquerque L, Da Silva M, Cararo Lopes E, et al. Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors. Mol Oncol. 2019;13:290-306 pubmed publisher
Eisemann T, Costa B, Harter P, Wick W, Mittelbronn M, Angel P, et al. Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma. Neuro Oncol. 2019;21:326-336 pubmed publisher
Ljepoja B, García Román J, Sommer A, Wagner E, Roidl A. MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators. Breast. 2019;43:31-38 pubmed publisher
Zhang P, Kang B, Xie G, Li S, Gu Y, Shen Y, et al. Genomic sequencing and editing revealed the GRM8 signaling pathway as potential therapeutic targets of squamous cell lung cancer. Cancer Lett. 2018;442:53-67 pubmed publisher
Kim D, Reyes Ordoñez A, Chen J. Lentivirus-Mediated RNAi in Skeletal Myogenesis. Methods Mol Biol. 2019;1889:95-110 pubmed publisher
Lee J, An J, Kang T, De D, Kim K. Discovery of Natural Compounds Promoting Cardiomyocyte Differentiation. Stem Cells Dev. 2019;28:13-27 pubmed publisher
Kosmidis S, Polyzos A, Harvey L, Youssef M, Denny C, Dranovsky A, et al. RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. Cell Rep. 2018;25:959-973.e6 pubmed publisher
Luong P, Hedl M, Yan J, Zuo T, Fu T, Jiang X, et al. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. elife. 2018;7: pubmed publisher
Mollaoglu G, Jones A, Wait S, Mukhopadhyay A, Jeong S, Arya R, et al. The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment. Immunity. 2018;49:764-779.e9 pubmed publisher
Odabas G, Cetin M, Turhal S, Baloglu H, Sayan A, Yagci T. Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma. Can J Gastroenterol Hepatol. 2018;2018:4040787 pubmed publisher
Hackett J, Huang Y, Günesdogan U, Gretarsson K, Kobayashi T, Surani M. Tracing the transitions from pluripotency to germ cell fate with CRISPR screening. Nat Commun. 2018;9:4292 pubmed publisher
Kim J, Alavi Naini F, Sun Y, Ma L. Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin. Am J Cancer Res. 2018;8:1823-1836 pubmed
Zolotarenko A, Chekalin E, Piruzian E, Bruskin S. FRA1 mediates the activation of keratinocytes: Implications for the development of psoriatic plaques. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3726-3734 pubmed publisher
Cai M, Li S, Shuai Y, Li J, Tan J, Zeng Q. Genome-wide CRISPR-Cas9 viability screen reveals genes involved in TNF-α-induced apoptosis of human umbilical vein endothelial cells. J Cell Physiol. 2019;234:9184-9193 pubmed publisher
Villiger L, Grisch Chan H, Lindsay H, Ringnalda F, Pogliano C, Allegri G, et al. Treatment of a metabolic liver disease by in vivo genome base editing in adult mice. Nat Med. 2018;24:1519-1525 pubmed publisher
Ungerleider N, Rao S, Shahbandi A, Yee D, Niu T, Frey W, et al. Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment. Breast Cancer Res. 2018;20:115 pubmed publisher
Luanpitpong S, Poohadsuan J, Samart P, Kiratipaiboon C, Rojanasakul Y, Issaragrisil S. Reactive oxygen species mediate cancer stem-like cells and determine bortezomib sensitivity via Mcl-1 and Zeb-1 in mantle cell lymphoma. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3739-3753 pubmed publisher
Emmer B, Hesketh G, Kotnik E, Tang V, Lascuna P, Xiang J, et al. The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9. elife. 2018;7: pubmed publisher
Zhang L, Li X, Chao Y, He R, Liu J, Yuan Y, et al. KLF4, a miR-32-5p targeted gene, promotes cisplatin-induced apoptosis by upregulating BIK expression in prostate cancer. Cell Commun Signal. 2018;16:53 pubmed publisher
Pane L, Fulcoli F, Cirino A, Altomonte A, Ferrentino R, Bilio M, et al. Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer. Dis Model Mech. 2018;11: pubmed publisher
Findlay S, Heath J, Luo V, Malina A, Morin T, Coulombe Y, et al. SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice. EMBO J. 2018;37: pubmed publisher
Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, et al. Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response. Nat Med. 2018;24:1550-1558 pubmed publisher
Al Ahdal M, Murugaiah V, Varghese P, Abozaid S, Saba I, Al Qahtani A, et al. Entry Inhibition and Modulation of Pro-Inflammatory Immune Response Against Influenza A Virus by a Recombinant Truncated Surfactant Protein D. Front Immunol. 2018;9:1586 pubmed publisher
Zhang D, Lin J, Chao Y, Zhang L, Jin L, Li N, et al. Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression. J Exp Clin Cancer Res. 2018;37:176 pubmed publisher
Riley J, Quarato G, Cloix C, Lopez J, O Prey J, Pearson M, et al. Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. EMBO J. 2018;37: pubmed publisher
Darnell A, Subramaniam A, O Shea E. Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells. Mol Cell. 2018;71:229-243.e11 pubmed publisher
Nadjsombati M, McGinty J, Lyons Cohen M, Jaffe J, DiPeso L, Schneider C, et al. Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit. Immunity. 2018;49:33-41.e7 pubmed publisher
Amick J, Tharkeshwar A, Amaya C, Ferguson S. WDR41 supports lysosomal response to changes in amino acid availability. Mol Biol Cell. 2018;29:2213-2227 pubmed publisher
Samavarchi Tehrani P, Abdouni H, Samson R, Gingras A. A Versatile Lentiviral Delivery Toolkit for Proximity-dependent Biotinylation in Diverse Cell Types. Mol Cell Proteomics. 2018;17:2256-2269 pubmed publisher
Brennan T, Lin L, Huang X, Yang Y. Generation of Luciferase-expressing Tumor Cell Lines. Bio Protoc. 2018;8: pubmed publisher
Garri C, Howell S, Tiemann K, Tiffany A, Jalali Yazdi F, Alba M, et al. Identification, characterization and application of a new peptide against anterior gradient homolog 2 (AGR2). Oncotarget. 2018;9:27363-27379 pubmed publisher
Liu X, Zhang Y, Chen Y, Li M, Shao Z, Zhang M, et al. CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9. Curr Protoc Mol Biol. 2018;123:e64 pubmed publisher
Birnbaum M, Nemzow L, Kumar A, Gong F, Zhang F. A Rapid and Precise Mutation-Activated Fluorescence Reporter for Analyzing Acute Mutagenesis Frequency. Cell Chem Biol. 2018;25:1038-1049.e5 pubmed publisher
El Badawy A, Ghoneim N, Nasr M, Elkhenany H, Ahmed T, Ahmed S, et al. Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells. Biol Open. 2018;7: pubmed publisher
Coyne E, Bedard N, Wykes L, Stretch C, Jammoul S, Li S, et al. Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling. Endocrinology. 2018;159:2966-2977 pubmed publisher
LI Y, Du L, Aldana Masangkay G, Wang X, Urak R, Forman S, et al. Regulation of miR-34b/c-targeted gene expression program by SUMOylation. Nucleic Acids Res. 2018;: pubmed publisher
Haapaniemi E, Botla S, Persson J, Schmierer B, Taipale J. CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response. Nat Med. 2018;24:927-930 pubmed publisher
Lv L, Wang Q, Xu Y, Tsao L, Nakagawa T, Guo H, et al. Vpr Targets TET2 for Degradation by CRL4VprBP E3 Ligase to Sustain IL-6 Expression and Enhance HIV-1 Replication. Mol Cell. 2018;70:961-970.e5 pubmed publisher
Weyn Vanhentenryck S, Feng H, Ustianenko D, Duffié R, Yan Q, Jacko M, et al. Precise temporal regulation of alternative splicing during neural development. Nat Commun. 2018;9:2189 pubmed publisher
Sanchez D, Steger D, Skuli N, Bansal A, Simon M. PPARγ is dispensable for clear cell renal cell carcinoma progression. Mol Metab. 2018;14:139-149 pubmed publisher
McKinley K. Employing CRISPR/Cas9 genome engineering to dissect the molecular requirements for mitosis. Methods Cell Biol. 2018;144:75-105 pubmed publisher
Ng S, Yoshida N, Christie A, Ghandi M, Dharia N, Dempster J, et al. Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models. Nat Commun. 2018;9:2024 pubmed publisher
Yang T, Chong W, Wang W, Mazo G, Tanos B, Chen Z, et al. Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components. Nat Commun. 2018;9:2023 pubmed publisher
Bhattacharjee S, Bose P, Patel K, Roy S, Gain C, Gowda H, et al. Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival. Cell Death Dis. 2018;9:605 pubmed publisher
Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, et al. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018;37:4941-4954 pubmed publisher
Kannappan R, Mattapally S, Wagle P, Zhang J. Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. Am J Physiol Heart Circ Physiol. 2018;315:H512-H521 pubmed publisher
Wang L, Leite De Oliveira R, Huijberts S, Bosdriesz E, Pencheva N, Brunen D, et al. An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential. Cell. 2018;173:1413-1425.e14 pubmed publisher
Ryu K, Nandu T, Kim J, Challa S, DeBerardinis R, Kraus W. Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis. Science. 2018;360: pubmed publisher
Roders N, Herr F, Ambroise G, Thaunat O, Portier A, Vazquez A, et al. SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production. Front Immunol. 2018;9:787 pubmed publisher
Schiller L, Lemus Diaz N, Rinaldi Ferreira R, Böker K, Gruber J. Enhanced Production of Exosome-Associated AAV by Overexpression of the Tetraspanin CD9. Mol Ther Methods Clin Dev. 2018;9:278-287 pubmed publisher
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
Mukhamedshina Y, Akhmetzyanova E, Kostennikov A, Zakirova E, Galieva L, Garanina E, et al. Adipose-Derived Mesenchymal Stem Cell Application Combined With Fibrin Matrix Promotes Structural and Functional Recovery Following Spinal Cord Injury in Rats. Front Pharmacol. 2018;9:343 pubmed publisher
Li P, Jin Y, Qi F, Wu F, Luo S, Cheng Y, et al. SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65. Front Cell Infect Microbiol. 2018;8:113 pubmed publisher
Bambousková M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, et al. Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis. Nature. 2018;556:501-504 pubmed publisher
Xu B, Deng Y, Bi R, Guo H, Shu C, Shah N, et al. A first-in-class inhibitor, MLN4924 (pevonedistat), induces cell-cycle arrest, senescence, and apoptosis in human renal cell carcinoma by suppressing UBE2M-dependent neddylation modification. Cancer Chemother Pharmacol. 2018;81:1083-1093 pubmed publisher
Chan K, Wong O, Wong E, Chan K, Ip P, Tse K, et al. Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma. Int J Cancer. 2018;143:1456-1469 pubmed publisher
Canver M, Haeussler M, Bauer D, Orkin S, Sanjana N, Shalem O, et al. Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments. Nat Protoc. 2018;13:946-986 pubmed publisher
Mattapally S, Zhu W, Fast V, Gao L, Worley C, Kannappan R, et al. Spheroids of cardiomyocytes derived from human-induced pluripotent stem cells improve recovery from myocardial injury in mice. Am J Physiol Heart Circ Physiol. 2018;315:H327-H339 pubmed publisher
Streck N, Carmichael J, Buchkovich N. Nonenvelopment Role for the ESCRT-III Complex during Human Cytomegalovirus Infection. J Virol. 2018;92: pubmed publisher
Sena Esteves M, Gao G. Production of High-Titer Retrovirus and Lentivirus Vectors. Cold Spring Harb Protoc. 2018;2018:pdb.prot095687 pubmed publisher
Jallow F, Brockman J, Helzer K, Rugowski D, Goffin V, Alarid E, et al. 17?-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes. J Endocr Soc. 2018;2:293-309 pubmed publisher
Pagotto S, Veronese A, Soranno A, Lanuti P, Di Marco M, Russo M, et al. Hsa-miR-155-5p drives aneuploidy at early stages of cellular transformation. Oncotarget. 2018;9:13036-13047 pubmed publisher
Thekkeparambil Chandrabose S, Sriram S, Subramanian S, Cheng S, Ong W, Rozen S, et al. Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming. Stem Cell Res Ther. 2018;9:68 pubmed publisher
Ledger S, Howe A, Turville S, Aggarwal A, Savkovic B, Ong A, et al. Analysis and dissociation of anti-HIV effects of shRNA to CCR5 and the fusion inhibitor C46. J Gene Med. 2018;20:e3006 pubmed publisher
Suphatrakul A, Duangchinda T, Jupatanakul N, Prasittisa K, Onnome S, Pengon J, et al. Multi-color fluorescent reporter dengue viruses with improved stability for analysis of a multi-virus infection. PLoS ONE. 2018;13:e0194399 pubmed publisher
Johnson J, Lucas S, Amon L, Skelton S, Nazitto R, Carbonetti S, et al. Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection. Cell Host Microbe. 2018;23:366-381.e9 pubmed publisher
Sprague L, Lee J, Hutzen B, Wang P, Chen C, Conner J, et al. High Mobility Group Box 1 Influences HSV1716 Spread and Acts as an Adjuvant to Chemotherapy. Viruses. 2018;10: pubmed publisher
Bonfim Melo A, Ferreira d, Mortara R. Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. Front Microbiol. 2018;9:360 pubmed publisher
Chen W, Freinkman E, Sabatini D. Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites. Nat Protoc. 2017;12:2215-2231 pubmed publisher
Shimobayashi M, Albert V, Woelnerhanssen B, Frei I, Weissenberger D, Meyer Gerspach A, et al. Insulin resistance causes inflammation in adipose tissue. J Clin Invest. 2018;128:1538-1550 pubmed publisher
Sakabe T, Sakai K, Maeda T, Sunaga A, Furuta N, Schweitzer R, et al. Transcription factor scleraxis vitally contributes to progenitor lineage direction in wound healing of adult tendon in mice. J Biol Chem. 2018;293:5766-5780 pubmed publisher
Kim H, Kang M, Kim M, Shin Y, Chi S, Jeong J. Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence. Mol Cells. 2018;41:362-372 pubmed publisher
Wang C, Zhou H, Xue Y, Liang J, Narita Y, Gerdt C, et al. Epstein-Barr Virus Nuclear Antigen Leader Protein Coactivates EP300. J Virol. 2018;92: pubmed publisher
Novas R, Cardenas Rodriguez M, Lepanto P, Fabregat M, Rodao M, Fariello M, et al. Kinesin 1 regulates cilia length through an interaction with the Bardet-Biedl syndrome related protein CCDC28B. Sci Rep. 2018;8:3019 pubmed publisher
Bogdan D, Falcone J, Kanjiya M, Park S, Carbonetti G, Studholme K, et al. Fatty acid-binding protein 5 controls microsomal prostaglandin E synthase 1 (mPGES-1) induction during inflammation. J Biol Chem. 2018;293:5295-5306 pubmed publisher
Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, et al. MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development. J Exp Clin Cancer Res. 2018;37:28 pubmed publisher
Everman J, Rios C, Seibold M. Primary Airway Epithelial Cell Gene Editing Using CRISPR-Cas9. Methods Mol Biol. 2018;1706:267-292 pubmed publisher
Chen L, Chen J, Huang Y, Gu Y, Qiu J, Qian H, et al. The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations. Mol Cell. 2018;69:412-425.e6 pubmed publisher
Fok J, Hedayat S, Zhang L, Aronson L, Mirabella F, Pawlyn C, et al. HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target. Clin Cancer Res. 2018;24:2395-2407 pubmed publisher
Mulye M, Zapata B, Gilk S. Altering lipid droplet homeostasis affects Coxiella burnetii intracellular growth. PLoS ONE. 2018;13:e0192215 pubmed publisher
Palau A, Garz A, Diesch J, Zwick A, Malinverni R, Valero V, et al. Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes. Oncotarget. 2017;8:115002-115017 pubmed publisher
Moser S, Voerman J, Buckley D, Winter G, Schliehe C. Acute Pharmacologic Degradation of a Stable Antigen Enhances Its Direct Presentation on MHC Class I Molecules. Front Immunol. 2017;8:1920 pubmed publisher
Zhao G, Huang B, Rigueur D, Wang W, Bhoot C, Charles K, et al. CYR61/CCN1 Regulates Sclerostin Levels and Bone Maintenance. J Bone Miner Res. 2018;33:1076-1089 pubmed publisher
Jiang S, Wang L, Walsh M, Trudeau S, Gerdt C, Zhao B, et al. CRISPR/Cas9-Mediated Genome Editing in Epstein-Barr Virus-Transformed Lymphoblastoid B-Cell Lines. Curr Protoc Mol Biol. 2018;121:31.12.1-31.12.23 pubmed publisher
Ambrogio C, Köhler J, Zhou Z, Wang H, Paranal R, Li J, et al. KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS. Cell. 2018;172:857-868.e15 pubmed publisher
Gell J, Zhao J, Chen D, Hunt T, Clark A. PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. Stem Cell Res. 2018;27:46-56 pubmed publisher
Fink D, Sun M, Heyne G, Everson J, Chung H, Park S, et al. Coordinated d-cyclin/Foxd1 activation drives mitogenic activity of the Sonic Hedgehog signaling pathway. Cell Signal. 2018;44:1-9 pubmed publisher
Kudo T, Jeknic S, Macklin D, Akhter S, Hughey J, Regot S, et al. Live-cell measurements of kinase activity in single cells using translocation reporters. Nat Protoc. 2018;13:155-169 pubmed publisher
Kim N, Minami N, Yamada M, Imai H. Immobilized pH in culture reveals an optimal condition for somatic cell reprogramming and differentiation of pluripotent stem cells. Reprod Med Biol. 2017;16:58-66 pubmed publisher
Najm F, Strand C, Donovan K, Hegde M, Sanson K, Vaimberg E, et al. Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens. Nat Biotechnol. 2018;36:179-189 pubmed publisher
Larabee J, Hauck G, Ballard J. Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin. J Biol Chem. 2018;293:1810-1819 pubmed publisher
Zhang Z, Fan Y, Xie F, Zhou H, Jin K, Shao L, et al. Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7. Nat Commun. 2017;8:2116 pubmed publisher
Sobocińska J, Roszczenko Jasińska P, Zareba Kozioł M, Hromada Judycka A, Matveichuk O, Traczyk G, et al. Lipopolysaccharide Upregulates Palmitoylated Enzymes of the Phosphatidylinositol Cycle: An Insight from Proteomic Studies. Mol Cell Proteomics. 2018;17:233-254 pubmed publisher
Evavold C, Ruan J, Tan Y, Xia S, Wu H, Kagan J. The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages. Immunity. 2018;48:35-44.e6 pubmed publisher
Kidan N, Khamaisie H, Ruimi N, Roitman S, Eshel E, Dally N, et al. Ectopic Expression of Snail and Twist in Ph+ Leukemia Cells Upregulates CD44 Expression and Alters Their Differentiation Potential. J Cancer. 2017;8:3952-3968 pubmed publisher
Hirano J, Okamoto T, Sugiyama Y, Suzuki T, Kusakabe S, Tokunaga M, et al. Characterization of SPP inhibitors suppressing propagation of HCV and protozoa. Proc Natl Acad Sci U S A. 2017;114:E10782-E10791 pubmed publisher
Germano G, Lamba S, Rospo G, Barault L, Magrì A, Maione F, et al. Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth. Nature. 2017;552:116-120 pubmed publisher
Sebrell T, Sidar B, Bruns R, Wilkinson R, Wiedenheft B, Taylor P, et al. Live imaging analysis of human gastric epithelial spheroids reveals spontaneous rupture, rotation and fusion events. Cell Tissue Res. 2018;371:293-307 pubmed publisher
Taipale M. Quantitative Profiling of Chaperone/Client Interactions with LUMIER Assay. Methods Mol Biol. 2018;1709:47-58 pubmed publisher
Li G, Montgomery J, Eckert M, Chang J, Tienda S, Lengyel E, et al. An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells. Nat Commun. 2017;8:1775 pubmed publisher
Segatto M, Fittipaldi R, Pin F, Sartori R, Dae Ko K, Zare H, et al. Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival. Nat Commun. 2017;8:1707 pubmed publisher
Meyerson N, Zhou L, Guo Y, Zhao C, Tao Y, Krug R, et al. Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation. Cell Host Microbe. 2017;22:627-638.e7 pubmed publisher
Blakely C, Watkins T, Wu W, Gini B, Chabon J, McCoach C, et al. Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. Nat Genet. 2017;49:1693-1704 pubmed publisher
Moder M, Velimezi G, Owusu M, Mazouzi A, Wiedner M, Ferreira da Silva J, et al. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nat Commun. 2017;8:1238 pubmed publisher
Barter M, Gomez R, Hyatt S, Cheung K, Skelton A, Xu Y, et al. The long non-coding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells. Development. 2017;144:4510-4521 pubmed publisher
Parisi L, Li N, Atilla Gokcumen G. Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis. Cell Chem Biol. 2017;24:1445-1454.e8 pubmed publisher
Wang Y, Chen L, Tian Z, Shen X, Wang X, Wu H, et al. CRISPR-Cas9 mediated gene knockout in human coronary artery endothelial cells reveals a pro-inflammatory role of TLR2. Cell Biol Int. 2018;42:187-193 pubmed publisher
Reddy A, Zhang J, Davis N, Moffitt A, Love C, Waldrop A, et al. Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017;171:481-494.e15 pubmed publisher
Lombardi M, Gillieron C, Berkelaar M, Gabay C. Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesis. PLoS ONE. 2017;12:e0185426 pubmed publisher
Thiepold A, Lorenz N, Foltyn M, Engel A, Divé I, Urban H, et al. Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death. Brain. 2017;140:2623-2638 pubmed publisher
Go D, Lee Y, Lee D, Kim J, Jo I, Han Y, et al. 3-Decylcatechol induces autophagy-mediated cell death through the IRE1?/JNK/p62 in hepatocellular carcinoma cells. Oncotarget. 2017;8:58790-58800 pubmed publisher
Fok K, Bose R, Sheng K, Chang C, Katz Egorov M, Culty M, et al. Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response. Endocrinology. 2017;158:4000-4016 pubmed publisher
Voronkova M, Luanpitpong S, Rojanasakul L, Castranova V, Dinu C, Riedel H, et al. SOX9 Regulates Cancer Stem-Like Properties and Metastatic Potential of Single-Walled Carbon Nanotube-Exposed Cells. Sci Rep. 2017;7:11653 pubmed publisher
Luanpitpong S, Angsutararux P, Samart P, Chanthra N, Chanvorachote P, Issaragrisil S. Hyper-O-GlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma. Sci Rep. 2017;7:10607 pubmed publisher
Napier B, Monack D. Creating a RAW264.7 CRISPR-Cas9 Genome Wide Library. Bio Protoc. 2017;7: pubmed publisher
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed publisher
Kim S, Yang C, Lee H, Kim J, Kim Y, Kim Y, et al. ESRRA (estrogen-related receptor α) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense. Autophagy. 2018;14:152-168 pubmed publisher
Rocchi A, Yamamoto S, Ting T, Fan Y, SADLEIR K, Wang Y, et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet. 2017;13:e1006962 pubmed publisher
Wanet A, Caruso M, Domelevo Entfellner J, Najar M, Fattaccioli A, Demazy C, et al. The Transcription Factor 7-Like 2-Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Axis Connects Mitochondrial Biogenesis and Metabolic Shift with Stem Cell Commitment to Hepatic Differentiation. Stem Cells. 2017;35:2184-2197 pubmed publisher
Kim M, Choi O, Pyo S, Choi S, Park C. Identification of novel ALK2 inhibitors and their effect on cancer cells. Biochem Biophys Res Commun. 2017;492:121-127 pubmed publisher
Plebani R, Tripaldi R, Lanuti P, Recchiuti A, Patruno S, Di Silvestre S, et al. Establishment and long-term culture of human cystic fibrosis endothelial cells. Lab Invest. 2017;97:1375-1384 pubmed publisher
Debaize L, Jakobczyk H, Rio A, Gandemer V, Troadec M. Optimization of proximity ligation assay (PLA) for detection of protein interactions and fusion proteins in non-adherent cells: application to pre-B lymphocytes. Mol Cytogenet. 2017;10:27 pubmed publisher
Stewart A, Kendziorski G, Deak Z, Brown D, Fini M, Copely K, et al. Co-transplantation of mesenchymal and neural stem cells and overexpressing stromal-derived factor-1 for treating spinal cord injury. Brain Res. 2017;1672:91-105 pubmed publisher
Deng W, McLaughlin S, Klinke D. Quantifying spontaneous metastasis in a syngeneic mouse melanoma model using real time PCR. Analyst. 2017;142:2945-2953 pubmed publisher
Conway D, Coon B, Budatha M, Arsenovic P, Orsenigo F, Wessel F, et al. VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN. Curr Biol. 2017;27:2219-2225.e5 pubmed publisher
Sakil H, Stantic M, Wolfsberger J, Brage S, Hansson J, Wilhelm M. ?Np73 regulates the expression of the multidrug-resistance genes ABCB1 and ABCB5 in breast cancer and melanoma cells - a short report. Cell Oncol (Dordr). 2017;40:631-638 pubmed publisher
Feng Q, Jagannathan S, Bradley R. The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity. Mol Cell. 2017;67:239-251.e6 pubmed publisher
Anuj -, Arivazhagan L, Surabhi R, Kanakarajan A, Sundaram S, Pitani R, et al. KIBRA attains oncogenic activity by repressing RASSF1A. Br J Cancer. 2017;: pubmed publisher
Carlson S, Soulette C, Yang Z, Elias J, Brooks A, Gozani O. RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation. J Biol Chem. 2017;292:13381-13390 pubmed publisher
Hein L, Apaja P, Hattersley K, Grose R, Xie J, Proud C, et al. A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome. Biochim Biophys Acta Mol Cell Res. 2017;1864:1554-1565 pubmed publisher
Kanie T, Abbott K, Mooney N, Plowey E, Demeter J, JACKSON P. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev Cell. 2017;42:22-36.e12 pubmed publisher
Lamborn I, Jing H, Zhang Y, DRUTMAN S, Abbott J, Munir S, et al. Recurrent rhinovirus infections in a child with inherited MDA5 deficiency. J Exp Med. 2017;214:1949-1972 pubmed publisher
Dave K, Sur I, Yan J, Zhang J, Kaasinen E, Zhong F, et al. Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth. elife. 2017;6: pubmed publisher
Zhao X, Wang X, Fang L, Lan C, Zheng X, Wang Y, et al. A combinatorial strategy using YAP and pan-RAF inhibitors for treating KRAS-mutant pancreatic cancer. Cancer Lett. 2017;402:61-70 pubmed publisher
Wang W, Jin Y, Zeng N, Ruan Q, Qian F. SOD2 Facilitates the Antiviral Innate Immune Response by Scavenging Reactive Oxygen Species. Viral Immunol. 2017;30:582-589 pubmed publisher
Jaiswal A, Peddinti G, Akimov Y, Wennerberg K, Kuznetsov S, Tang J, et al. Seed-effect modeling improves the consistency of genome-wide loss-of-function screens and identifies synthetic lethal vulnerabilities in cancer cells. Genome Med. 2017;9:51 pubmed publisher
Quirós P, Prado M, Zamboni N, D Amico D, Williams R, Finley D, et al. Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals. J Cell Biol. 2017;216:2027-2045 pubmed publisher
Nappo G, Handle F, Santer F, McNeill R, Seed R, Collins A, et al. The immunosuppressive cytokine interleukin-4 increases the clonogenic potential of prostate stem-like cells by activation of STAT6 signalling. Oncogenesis. 2017;6:e342 pubmed publisher
Vanoli F, Jasin M. Generation of chromosomal translocations that lead to conditional fusion protein expression using CRISPR-Cas9 and homology-directed repair. Methods. 2017;121-122:138-145 pubmed publisher
Shimokawa C, Kanaya T, Hachisuka M, Ishiwata K, Hisaeda H, Kurashima Y, et al. Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections. Immunity. 2017;46:863-874.e4 pubmed publisher
Ma Y, Walsh M, Bernhardt K, Ashbaugh C, Trudeau S, Ashbaugh I, et al. CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors. Cell Host Microbe. 2017;21:580-591.e7 pubmed publisher
Monge C, DiStasio N, Rossi T, Sébastien M, Sakai H, Kalman B, et al. Quiescence of human muscle stem cells is favored by culture on natural biopolymeric films. Stem Cell Res Ther. 2017;8:104 pubmed publisher
Schneider R, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, van Strien P, et al. Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell. 2017;20:785-800.e8 pubmed publisher
Rohrbach T, Jones R, Hicks P, Weaver A, Cooper T, Eustace N, et al. MARCKS phosphorylation is modulated by a peptide mimetic of MARCKS effector domain leading to increased radiation sensitivity in lung cancer cell lines. Oncol Lett. 2017;13:1216-1222 pubmed publisher
Strezoska Z, Perkett M, Chou E, Maksimova E, Anderson E, McClelland S, et al. High-content analysis screening for cell cycle regulators using arrayed synthetic crRNA libraries. J Biotechnol. 2017;251:189-200 pubmed publisher
Toriyama M, Toriyama M, Wallingford J, Finnell R. Folate-dependent methylation of septins governs ciliogenesis during neural tube closure. FASEB J. 2017;31:3622-3635 pubmed publisher
Hastings A, Yockey L, Jagger B, Hwang J, Uraki R, Gaitsch H, et al. TAM Receptors Are Not Required for Zika Virus Infection in Mice. Cell Rep. 2017;19:558-568 pubmed publisher
Verusingam N, Yeap S, Ky H, Paterson I, Khoo S, Cheong S, et al. Susceptibility of Human Oral Squamous Cell Carcinoma (OSCC) H103 and H376 cell lines to Retroviral OSKM mediated reprogramming. Peerj. 2017;5:e3174 pubmed publisher
Fu Q, Chen K, Zhu Q, Wang W, Huang F, Miao L, et al. ?-catenin promotes intracellular bacterial killing via suppression of Pseudomonas aeruginosa-triggered macrophage autophagy. J Int Med Res. 2017;45:556-569 pubmed publisher
Vyas R, Meredith D, Lane R. Lysine-specific demethylase-1 (LSD1) depletion disrupts monogenic and monoallelic odorant receptor (OR) expression in an olfactory neuronal cell line. Mol Cell Neurosci. 2017;82:1-11 pubmed publisher
Xu Y, Wang X, Chen Y, Chen S, Yang X, Sun Y, et al. Integration of Receptor Tyrosine Kinases Determines Sensitivity to PI3K?-selective Inhibitors in Breast Cancer. Theranostics. 2017;7:974-986 pubmed publisher
Morita S, Villalta S, Feldman H, Register A, Rosenthal W, Hoffmann Petersen I, et al. Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes. Cell Metab. 2017;25:883-897.e8 pubmed publisher
Stratford J, Yan F, Hill R, Major M, Graves L, Der C, et al. Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability. PLoS ONE. 2017;12:e0174863 pubmed publisher
Takayama K, Matsuura A, Itakura E. Dissection of ubiquitinated protein degradation by basal autophagy. FEBS Lett. 2017;591:1199-1211 pubmed publisher
Kolli N, Lu M, Maiti P, Rossignol J, Dunbar G. CRISPR-Cas9 Mediated Gene-Silencing of the Mutant Huntingtin Gene in an In Vitro Model of Huntington's Disease. Int J Mol Sci. 2017;18: pubmed publisher
Liu W, Chen H, Wong N, Haynes W, Baker C, Wang X. Pseudohypoxia induced by miR-126 deactivation promotes migration and therapeutic resistance in renal cell carcinoma. Cancer Lett. 2017;394:65-75 pubmed publisher
Riddick G, Kotliarova S, Rodriguez V, Kim H, Linkous A, Storaska A, et al. A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity. Sci Rep. 2017;7:43605 pubmed publisher
Qiu H, Zhong J, Luo L, Tang Z, Liu N, Kang K, et al. Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation. Int J Biol Sci. 2017;13:157-166 pubmed publisher
Huang X, Zhou G, Wu W, Ma G, D Amore P, Mukai S, et al. Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation. Invest Ophthalmol Vis Sci. 2017;58:1228-1236 pubmed publisher
Donovan K, Hegde M, Sullender M, Vaimberg E, Johannessen C, Root D, et al. Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool. PLoS ONE. 2017;12:e0170445 pubmed publisher
Rahman A, Haugh J. Kinetic Modeling and Analysis of the Akt/Mechanistic Target of Rapamycin Complex 1 (mTORC1) Signaling Axis Reveals Cooperative, Feedforward Regulation. J Biol Chem. 2017;292:2866-2872 pubmed publisher
Araujo T, Zeidler J, Oliveira P, Dias M, Armelin H, Laurindo F. Protein disulfide isomerase externalization in endothelial cells follows classical and unconventional routes. Free Radic Biol Med. 2017;103:199-208 pubmed publisher
Ocampo A, Reddy P, Martínez Redondo P, Platero Luengo A, Hatanaka F, Hishida T, et al. In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming. Cell. 2016;167:1719-1733.e12 pubmed publisher
Marmisolle I, Martínez J, Liu J, Mastrogiovanni M, Fergusson M, Rovira I, et al. Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation. Arch Biochem Biophys. 2017;613:12-22 pubmed publisher
Tsetsenis T. Monitoring Synapses Via Trans-Synaptic GFP Complementation. Methods Mol Biol. 2017;1538:45-52 pubmed
Wei W, Guo H, Chang J, Yu Y, Liu G, Zhang N, et al. ICAM-5/Telencephalin Is a Functional Entry Receptor for Enterovirus D68. Cell Host Microbe. 2016;20:631-641 pubmed publisher
Zhu P, Wang Y, Wu J, Huang G, Liu B, Ye B, et al. LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells. Nat Commun. 2016;7:13608 pubmed publisher
Okashita N, Suwa Y, Nishimura O, Sakashita N, Kadota M, Nagamatsu G, et al. PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency. Stem Cell Reports. 2016;7:1072-1086 pubmed publisher
Lee M, Sumpter R, Zou Z, Sirasanagandla S, Wei Y, Mishra P, et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017;18:48-60 pubmed publisher
Wang J, Qiao L, Hou Z, Luo G. TIM-1 Promotes Hepatitis C Virus Cell Attachment and Infection. J Virol. 2017;91: pubmed publisher
Zhang Y, Fang X, Dai M, Cao Q, Tan T, He W, et al. Cardiac-specific down-regulation of carnitine palmitoyltransferase-1b (CPT-1b) prevents cardiac remodeling in obese mice. Obesity (Silver Spring). 2016;24:2533-2543 pubmed publisher
Leithner A, Eichner A, Muller J, Reversat A, Brown M, Schwarz J, et al. Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. Nat Cell Biol. 2016;18:1253-1259 pubmed publisher
Won H, de la Torre Ubieta L, Stein J, Parikshak N, Huang J, Opland C, et al. Chromosome conformation elucidates regulatory relationships in developing human brain. Nature. 2016;538:523-527 pubmed publisher
Ni T, Li X, Lu N, An T, Liu Z, Fu R, et al. Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer. Nat Cell Biol. 2016;18:1221-1232 pubmed publisher
Bulanova D, Akimov Y, Rokka A, Laajala T, Aittokallio T, Kouvonen P, et al. Orphan G protein-coupled receptor GPRC5A modulates integrin ?1-mediated epithelial cell adhesion. Cell Adh Migr. 2017;11:434-446 pubmed publisher
Dugina V, Alieva I, Khromova N, Kireev I, Gunning P, Kopnin P. Interaction of microtubules with the actin cytoskeleton via cross-talk of EB1-containing +TIPs and γ-actin in epithelial cells. Oncotarget. 2016;7:72699-72715 pubmed publisher
Tong B, Lee C, Cheng W, Lai K, Foskett J, Cheung K. Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry. Sci Signal. 2016;9:ra89 pubmed publisher
Arakawa H. A method to convert mRNA into a gRNA library for CRISPR/Cas9 editing of any organism. Sci Adv. 2016;2:e1600699 pubmed publisher
Josowitz R, Mulero Navarro S, Rodriguez N, Falce C, Cohen N, Ullian E, et al. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports. 2016;7:355-369 pubmed publisher
Zhang T, Xue L, Li L, Tang C, Wan Z, Wang R, et al. BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy. J Biol Chem. 2016;291:21616-21629 pubmed
Kaminski R, Chen Y, Salkind J, Bella R, Young W, Ferrante P, et al. Negative Feedback Regulation of HIV-1 by Gene Editing Strategy. Sci Rep. 2016;6:31527 pubmed publisher
Ma G, Duan Y, Huang X, Qian C, Chee Y, Mukai S, et al. Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases. Invest Ophthalmol Vis Sci. 2016;57:3935-43 pubmed publisher
Du L, LI Y, Fakih M, Wiatrek R, Duldulao M, Chen Z, et al. Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal. Nat Commun. 2016;7:12326 pubmed publisher
Guo Y, Ma J, Zheng Y, Li L, Gui X, Wang Q, et al. HPV16 E6 upregulates Aurora A expression. Oncol Lett. 2016;12:1387-1393 pubmed
Chidley C, Trauger S, Birsoy K, O Shea E. The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine. elife. 2016;5: pubmed publisher
Liang C, Xu Y, Zheng D, Sun X, Xu Q, Duan D. RNAi-mediated silencing of HLA A2 suppressed acute rejection against human fibroblast xenografts in the striatum of 6-OHDA lesioned rats. J Neuroimmunol. 2016;297:28-37 pubmed publisher
Oki K, Plonczynski M, Gomez Sanchez E, Gomez Sanchez C. YPEL4 modulates HAC15 adrenal cell proliferation and is associated with tumor diameter. Mol Cell Endocrinol. 2016;434:93-8 pubmed publisher
Wang Y, Sun S, Liu Q, Yu Y, Guo J, Wang K, et al. Autocrine Complement Inhibits IL10-Dependent T-cell-Mediated Antitumor Immunity to Promote Tumor Progression. Cancer Discov. 2016;6:1022-35 pubmed publisher
Yi H, Zeng D, Shen Z, Liao J, Wang X, Liu Y, et al. Integrin alphavbeta3 enhances ?-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity. Oncotarget. 2016;7:40387-40397 pubmed publisher
Bartok E, Kampes M, Hornung V. Measuring IL-1? Processing by Bioluminescence Sensors II: The iGLuc System. Methods Mol Biol. 2016;1417:97-113 pubmed publisher
Jin C, Peng X, Liu F, Cheng L, Xie T, Lu X, et al. Interferon-induced sterile alpha motif and histidine/aspartic acid domain-containing protein 1 expression in astrocytes and microglia is mediated by microRNA-181a. AIDS. 2016;30:2053-64 pubmed publisher
Jones M, Jallepalli P. Engineering and Functional Analysis of Mitotic Kinases Through Chemical Genetics. Methods Mol Biol. 2016;1413:349-63 pubmed publisher
Tapia O, Gerace L. Analysis of Nuclear Lamina Proteins in Myoblast Differentiation by Functional Complementation. Methods Mol Biol. 2016;1411:177-94 pubmed publisher
Tosatto A, Sommaggio R, Kummerow C, Bentham R, Blacker T, Berecz T, et al. The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α. EMBO Mol Med. 2016;8:569-85 pubmed publisher
Jahani Asl A, Yin H, Soleimani V, Haque T, Luchman H, Chang N, et al. Control of glioblastoma tumorigenesis by feed-forward cytokine signaling. Nat Neurosci. 2016;19:798-806 pubmed publisher
Philippe C, Vargas Landin D, Doucet A, van Essen D, Vera Otarola J, Kuciak M, et al. Activation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive loci. elife. 2016;5: pubmed publisher
Song H, Park S, Kang H, Vassilopoulos A. Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates. J Vis Exp. 2016;:53563 pubmed publisher
Cheong T, Compagno M, Chiarle R. Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system. Nat Commun. 2016;7:10934 pubmed publisher
Wang T, Lander E, Sabatini D. Viral Packaging and Cell Culture for CRISPR-Based Screens. Cold Spring Harb Protoc. 2016;2016:pdb.prot090811 pubmed publisher
Mavuluri J, Beesetti S, Surabhi R, Kremerskothen J, Venkatraman G, Rayala S. Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells. Mol Cell Biol. 2016;36:1354-65 pubmed publisher
Chanvorachote P, Luanpitpong S. Iron induces cancer stem cells and aggressive phenotypes in human lung cancer cells. Am J Physiol Cell Physiol. 2016;310:C728-39 pubmed publisher
Malaver Ortega L, Sumer H, Liu J, Verma P. Inhibition of JAK-STAT ERK/MAPK and Glycogen Synthase Kinase-3 Induces a Change in Gene Expression Profile of Bovine Induced Pluripotent Stem Cells. Stem Cells Int. 2016;2016:5127984 pubmed publisher
Lee C, Tong B, Cheng C, Hung H, Cheung K. Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology. Sci Rep. 2016;6:20282 pubmed publisher
Puujalka E, Heinz M, Hoesel B, Friedl P, Schweighofer B, Wenzina J, et al. Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma. J Invest Dermatol. 2016;136:967-977 pubmed publisher
Malan D, Zhang M, Stallmeyer B, Müller J, Fleischmann B, Schulze Bahr E, et al. Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction. Basic Res Cardiol. 2016;111:14 pubmed publisher
Doench J, Fusi N, Sullender M, Hegde M, Vaimberg E, Donovan K, et al. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9. Nat Biotechnol. 2016;34:184-191 pubmed publisher
Guye P, Ebrahimkhani M, Kipniss N, Velazquez J, Schoenfeld E, Kiani S, et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun. 2016;7:10243 pubmed publisher
Beach J, Aspuria P, Cheon D, Lawrenson K, Agadjanian H, Walsh C, et al. Sphingosine kinase 1 is required for TGF-β mediated fibroblastto- myofibroblast differentiation in ovarian cancer. Oncotarget. 2016;7:4167-82 pubmed publisher
Chen X, Xue L, Hou S, Jin Z, Zhang T, Zheng F, et al. Long-acting cocaine hydrolase for addiction therapy. Proc Natl Acad Sci U S A. 2016;113:422-7 pubmed publisher
He J, Huang L, Qiu H, Li J, Luo L, Li Y, et al. A new design of a lentiviral shRNA vector with inducible co-expression of ARGONAUTE 2 for enhancing gene silencing efficiency. Cell Biosci. 2015;5:67 pubmed publisher
Qiu H, Zhong J, Luo L, Liu N, Kang K, Qu J, et al. A PCR-Based Method to Construct Lentiviral Vector Expressing Double Tough Decoy for miRNA Inhibition. PLoS ONE. 2015;10:e0143864 pubmed publisher
DeNicola G, Chen P, Mullarky E, Sudderth J, Hu Z, Wu D, et al. NRF2 regulates serine biosynthesis in non-small cell lung cancer. Nat Genet. 2015;47:1475-81 pubmed publisher
Rohrbach T, Shah N, Jackson W, Feeney E, Scanlon S, Gish R, et al. The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization. PLoS ONE. 2015;10:e0140870 pubmed publisher
Lee J, Tang S, Ortiz V, Vo T, Fruman D. MCL-1-independent mechanisms of synergy between dual PI3K/mTOR and BCL-2 inhibition in diffuse large B cell lymphoma. Oncotarget. 2015;6:35202-17 pubmed publisher
Luanpitpong S, Li J, Manke A, Brundage K, Ellis E, McLaughlin S, et al. SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma. Oncogene. 2016;35:2824-33 pubmed publisher
Elsarraj H, Hong Y, Valdez K, Michaels W, Hook M, Smith W, et al. Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion. Breast Cancer Res. 2015;17:128 pubmed publisher
Wollebo H, Bellizzi A, Kaminski R, Hu W, White M, Khalili K. CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection. PLoS ONE. 2015;10:e0136046 pubmed publisher
Basak P, Dillon R, Leslie H, Raouf A, Mowat M. The Deleted in Liver Cancer 1 (Dlc1) tumor suppressor is haploinsufficient for mammary gland development and epithelial cell polarity. BMC Cancer. 2015;15:630 pubmed publisher
Hirai H, Firpo M, Kikyo N. Derivation of LIF-independent mouse iPS cells with modified Oct4. Stem Cell Res. 2015;15:384-6 pubmed publisher
Zagani R, El Assaad W, Gamache I, Teodoro J. Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells. Oncotarget. 2015;6:28282-95 pubmed publisher
Simmons A, Alberola Ila J. Retroviral Transduction of T Cells and T Cell Precursors. Methods Mol Biol. 2016;1323:99-108 pubmed publisher
Wroblewska L, Kitada T, Endo K, Siciliano V, Stillo B, Saito H, et al. Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery. Nat Biotechnol. 2015;33:839-41 pubmed publisher
Wang B, Lee C, Witt A, Thakkar A, Ince T. Heat shock factor 1 induces cancer stem cell phenotype in breast cancer cell lines. Breast Cancer Res Treat. 2015;153:57-66 pubmed publisher
Rubtsova S, Zhitnyak I, Gloushankova N. A Novel Role of E-Cadherin-Based Adherens Junctions in Neoplastic Cell Dissemination. PLoS ONE. 2015;10:e0133578 pubmed publisher
Yuan J, Zhang Y, Sheng Y, Fu X, Cheng H, Zhou R. MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals. Autophagy. 2015;11:1081-98 pubmed publisher
Chu H, Rios C, Huang C, Wesolowska Andersen A, Burchard E, O Connor B, et al. CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18. Gene Ther. 2015;22:822-9 pubmed publisher
Zhang Y, Bao M, Dai M, Wang X, He W, Tan T, et al. Cardiospecific CD36 suppression by lentivirus-mediated RNA interference prevents cardiac hypertrophy and systolic dysfunction in high-fat-diet induced obese mice. Cardiovasc Diabetol. 2015;14:69 pubmed publisher
Witwicka H, Jia H, Kutikov A, Reyes Gutiérrez P, Li X, Odgren P. TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption. PLoS ONE. 2015;10:e0127537 pubmed publisher
Pan D, Jiang C, Ma Z, Blonska M, You M, Lin X. MALT1 is required for EGFR-induced NF-?B activation and contributes to EGFR-driven lung cancer progression. Oncogene. 2016;35:919-28 pubmed publisher
Fisher M, Adhikary G, Xu W, Kerr C, Keillor J, Eckert R. Type II transglutaminase stimulates epidermal cancer stem cell epithelial-mesenchymal transition. Oncotarget. 2015;6:20525-39 pubmed
Fisher M, Keillor J, Xu W, Eckert R, Kerr C. Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell Survival. Mol Cancer Res. 2015;13:1083-94 pubmed publisher
Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, et al. Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2. PLoS ONE. 2015;10:e0119727 pubmed publisher
Johnson H, King S, Asokan S, Rotty J, Bear J, Haugh J. F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling. J Cell Biol. 2015;208:443-55 pubmed publisher
Howard S, Yanez D, Stark J. DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining. PLoS Genet. 2015;11:e1004943 pubmed publisher
Mauger O, Klinck R, Chabot B, Muchardt C, Allemand E, Batsché E. Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions. Nucleic Acids Res. 2015;43:1869-82 pubmed publisher
Czarnecki P, Gabriel G, Manning D, Sergeev M, Lemke K, Klena N, et al. ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Nat Commun. 2015;6:6023 pubmed publisher
Pacheco L, Gomez L, Dias J, Ziebarth N, Howard G, Schiller P. Progerin expression disrupts critical adult stem cell functions involved in tissue repair. Aging (Albany NY). 2014;6:1049-63 pubmed
Duportet X, Wroblewska L, Guye P, Li Y, Eyquem J, Rieders J, et al. A platform for rapid prototyping of synthetic gene networks in mammalian cells. Nucleic Acids Res. 2014;42:13440-51 pubmed publisher
Charni Chaabane S, Coomans de Brachène A, Essaghir A, Velghe A, Lo Re S, Stockis J, et al. PDGF-D expression is down-regulated by TGFβ in fibroblasts. PLoS ONE. 2014;9:e108656 pubmed publisher
Götz R, Sendtner M. Cooperation of tyrosine kinase receptor TrkB and epidermal growth factor receptor signaling enhances migration and dispersal of lung tumor cells. PLoS ONE. 2014;9:e100944 pubmed publisher
Guo Y, Meng X, Ma J, Zheng Y, Wang Q, Wang Y, et al. Human papillomavirus 16 E6 contributes HIF-1? induced Warburg effect by attenuating the VHL-HIF-1? interaction. Int J Mol Sci. 2014;15:7974-86 pubmed publisher
Setta Kaffetzi N, Simpson M, Navarini A, Patel V, Lu H, Allen M, et al. AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking. Am J Hum Genet. 2014;94:790-7 pubmed publisher
Wutka A, Palagani V, Barat S, Chen X, El Khatib M, Götze J, et al. Capsaicin treatment attenuates cholangiocarcinoma carcinogenesis. PLoS ONE. 2014;9:e95605 pubmed publisher
Fischer S, Ronellenfitsch M, Thiepold A, Harter P, Reichert S, Kogel D, et al. Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid. PLoS ONE. 2014;9:e94921 pubmed publisher
Missan D, Chittur S, DiPersio C. Regulation of fibulin-2 gene expression by integrin ?3?1 contributes to the invasive phenotype of transformed keratinocytes. J Invest Dermatol. 2014;134:2418-2427 pubmed publisher
Joo E, Yamada K. MYPT1 regulates contractility and microtubule acetylation to modulate integrin adhesions and matrix assembly. Nat Commun. 2014;5:3510 pubmed publisher
Zhao P, Torcaso A, Mariano A, Xu L, Mohsin S, Zhao L, et al. Anoctamin 6 regulates C2C12 myoblast proliferation. PLoS ONE. 2014;9:e92749 pubmed publisher
Mallya S, Fitch B, Lee J, So L, Janes M, Fruman D. Resistance to mTOR kinase inhibitors in lymphoma cells lacking 4EBP1. PLoS ONE. 2014;9:e88865 pubmed publisher
Ablett M, O Brien C, Sims A, Farnie G, Clarke R. A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity. Oncotarget. 2014;5:599-612 pubmed
Leyton Mange J, Mills R, Macri V, Jang M, Butte F, Ellinor P, et al. Rapid cellular phenotyping of human pluripotent stem cell-derived cardiomyocytes using a genetically encoded fluorescent voltage sensor. Stem Cell Reports. 2014;2:163-70 pubmed publisher
Wang C, Qin L, Manes T, Kirkiles Smith N, Tellides G, Pober J. Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2. J Exp Med. 2014;211:395-404 pubmed publisher
Li Z, Dong L, Dean E, Yang L. Acidosis decreases c-Myc oncogene expression in human lymphoma cells: a role for the proton-sensing G protein-coupled receptor TDAG8. Int J Mol Sci. 2013;14:20236-55 pubmed publisher
Hong S, Kim J, Starenki D, Park J. Autophagy sensitivity of neuroendocrine lung tumor cells. Int J Oncol. 2013;43:2031-8 pubmed publisher
Guo Y, Meng X, Wang Q, Wang Y, Shang H. The ING4 Binding with p53 and Induced p53 Acetylation were Attenuated by Human Papillomavirus 16 E6. PLoS ONE. 2013;8:e71453 pubmed publisher
Matatall K, Agapova O, Onken M, Worley L, Bowcock A, Harbour J. BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma. BMC Cancer. 2013;13:371 pubmed publisher
Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel C, Höing S, et al. Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS ONE. 2013;8:e59252 pubmed publisher
Wang D, Wise M, Li F, Dey M. Phytochemicals attenuating aberrant activation of ?-catenin in cancer cells. PLoS ONE. 2012;7:e50508 pubmed publisher
Bajaj A, Li Q, Zheng Q, Pumiglia K. Loss of NF1 expression in human endothelial cells promotes autonomous proliferation and altered vascular morphogenesis. PLoS ONE. 2012;7:e49222 pubmed publisher
Griner S, Joshi J, Nahta R. Growth differentiation factor 15 stimulates rapamycin-sensitive ovarian cancer cell growth and invasion. Biochem Pharmacol. 2013;85:46-58 pubmed publisher
Frank S, Zhang M, Scholer H, Greber B. Small molecule-assisted, line-independent maintenance of human pluripotent stem cells in defined conditions. PLoS ONE. 2012;7:e41958 pubmed publisher
Scheibye Knudsen M, Ramamoorthy M, Sykora P, Maynard S, Lin P, Minor R, et al. Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. J Exp Med. 2012;209:855-69 pubmed publisher
Cai Q, Guo Y, Xiao B, Banerjee S, Saha A, Lu J, et al. Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosis. PLoS Pathog. 2011;7:e1002418 pubmed publisher
Patel S, Simon M. Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos. J Biol Chem. 2010;285:15587-98 pubmed publisher
Moretti A, Bellin M, Jung C, Thies T, Takashima Y, Bernshausen A, et al. Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. FASEB J. 2010;24:700-11 pubmed publisher
Byrne J, Nguyen H, Reijo Pera R. Enhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblasts. PLoS ONE. 2009;4:e7118 pubmed publisher
Kulkarni A, McNeill D, Gleichmann M, Mattson M, Wilson D. XRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cells. Nucleic Acids Res. 2008;36:5111-21 pubmed publisher
Stewart S, Dykxhoorn D, Palliser D, Mizuno H, Yu E, An D, et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA. 2003;9:493-501 pubmed
product information
Catalog Number :
8454
Product Name :
pCMV-VSV-G
article :
doi10.1261/rna.2192803
id190
pubmed_id12649500
bacterial resistance :
Ampicillin
cloning :
backbonena
backbone_mutation
backbone_origin
backbone_size6363
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Envelope protein for producing lentiviral and MuLV retroviral particles. Use in conjunction with a packaging vector such as pCMV-dR8.2 dvpr (lentiviral) or pUMVC (MuLV retroviral).
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
genbank_ids
mutation
name
shRNA_sequence
size
species
tags
resistance markers :
568
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA