This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Hs.KRAS4b
catalog :
83129
citations: 4
Reference
Cuevas Navarro A, Wagner M, Van R, Swain M, Mo S, Columbus J, et al. RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophy. Sci Adv. 2023;9:eadf4766 pubmed publisher
McFall T, Stites E. Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach. Cell Rep. 2021;37:110096 pubmed publisher
Lee S, Jeon Y, Kang J, Jang H, Lee H, Kim S. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer. Cancers (Basel). 2020;12: pubmed publisher
McFall T, Diedrich J, Mengistu M, Littlechild S, Paskvan K, Sisk Hackworth L, et al. A systems mechanism for KRAS mutant allele-specific responses to targeted therapy. Sci Signal. 2019;12: pubmed publisher
product information
Catalog Number :
83129
Product Name :
Hs.KRAS4b
article :
doi
id22172
pubmed_id
bacterial resistance :
Spectinomycin
cloning :
backbonepDonor-255
backbone_mutation
backbone_origin
backbone_size2693
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Other
Gateway Entry Clone
growth strain :
Gateway ORF Entry clone of human KRAS4B [NM_004985.4 ] with stop codon (for native or N-terminal fusions)
origin :
37
pi :
alt_names
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3attLR 23-mer (5'-TAACATCAGAGATTTTGAGACAC)
sequencing_primer_5M13F 23-mer (5'-CCCAGTCACGACGTTGTAAAACG)
site_3_destroyed
site_5_destroyed
entrez_gene
aliases'C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2
geneKRAS
id3845
genbank_ids
NM_004985.4
mutation
nameKRAS
shRNA_sequence
size567
species
9606
Homo sapiens
tags
resistance markers :
139
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA