pDONR223_MYC_WT | Addgene 82927 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pDONR223_MYC_WT

catalog :

82927

citations: 3

Reference
Yashar W, Curtiss B, Coleman D, VanCampen J, Kong G, Macaraeg J, et al. Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia. Mol Cancer Res. 2023;21:631-647 pubmed publisher
Morris V, Wang D, Li Z, Marion W, Hughes T, Sousa P, et al. Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells. Cell Rep. 2022;39:110752 pubmed publisher
Berger A, Brooks A, Wu X, Shrestha Y, Chouinard C, Piccioni F, et al. High-throughput Phenotyping of Lung Cancer Somatic Mutations. Cancer Cell. 2016;30:214-228 pubmed publisher

product information

Catalog Number :

82927

Product Name :

pDONR223_MYC_WT

article :

doi	10.1016/j.ccell.2016.06.022
id	25588
pubmed_id	27478040

bacterial resistance :

Spectinomycin

cloning :

backbone

pDONR223

backbone_mutation

backbone_origin

Invitrogen

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Other

Gateway Entry vector

growth notes :

CLOSED (stop codon immediately follows insert) Plasmid pDONR223_MYC_WT is also present in the Broad's Target Accelerator Genetic Pathways- Reference Set (plasmid #82084).

growth strain :

Gateway Donor vector containing MYC, part of the Target Accelerator Plasmid Collection.

origin :

pi :

alt_names

NM_002467

cloning

clone_method	Gateway Cloning
cloning_site_3
cloning_site_5
promoter	None
sequencing_primer_3	M13-Rev
sequencing_primer_5	M13pUC-fwd
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	MRTL, MYCC, bHLHe39, c-Myc
gene	MYC
id	4609

genbank_ids

mutation

name

Myc

shRNA_sequence

size

species

9606

Homo sapiens