pDONR223_STAT3_WT | Addgene 82235 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pDONR223_STAT3_WT

catalog :

82235

citations: 4

Reference
Yoon J, Grinchuk O, Tirado Magallanes R, Ngian Z, Tay E, Chuah Y, et al. E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity. Cell Death Differ. 2022;: pubmed publisher
Remy J, Linder B, Weirauch U, Day B, Stringer B, Herold Mende C, et al. STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death. Cancers (Basel). 2022;14: pubmed publisher
Chen K, Yang W, Xuan Y, Lin A. miR-526b-3p inhibits lung cancer cisplatin-resistance and metastasis by inhibiting STAT3-promoted PD-L1. Cell Death Dis. 2021;12:748 pubmed publisher
Kim E, Ilic N, Shrestha Y, Zou L, Kamburov A, Zhu C, et al. Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles. Cancer Discov. 2016;6:714-26 pubmed publisher

product information

Catalog Number :

82235

Product Name :

pDONR223_STAT3_WT

article :

doi	10.1158/2159-8290.CD-16-0160
id	22007
pubmed_id	27147599

bacterial resistance :

Spectinomycin

cloning :

backbone

pDONR223

backbone_mutation

backbone_origin

Invitrogen

backbone_size

2790

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Other

Gateway Entry vector

growth notes :

Open state: NO stop codon immediately follows insert. Supporting reference: Systematic morphological profiling of human gene and allele function via Cell Painting. Rohban MH, et al. Elife. 2017, Mar 18;6. pii: e24060. PubMed PMID 28315521

growth strain :

Gateway Donor vector containing STAT3, part of the Target Accelerator Plasmid Collection.

origin :

pi :

alt_names

NM_139276.2

cloning

clone_method	Gateway Cloning
cloning_site_3
cloning_site_5
promoter	None
sequencing_primer_3	M13-Rev
sequencing_primer_5	M13pUC-fwd
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	ADMIO, ADMIO1, APRF, HIES
gene	STAT3
id	6774

genbank_ids

mutation

name

STAT3

shRNA_sequence

size

species

9606

Homo sapiens