pDONR223_STAT3_p.A662C_N664C | Addgene 82184 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pDONR223_STAT3_p.A662C_N664C

catalog :

82184

citations: 2

Reference
Lu D, Nagelberg A, Chow J, Chen Y, Michalchuk Q, Somwar R, et al. MET Exon 14 Splice-Site Mutations Preferentially Activate KRAS Signaling to Drive Tumourigenesis. Cancers (Basel). 2022;14: pubmed publisher
Kim E, Ilic N, Shrestha Y, Zou L, Kamburov A, Zhu C, et al. Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles. Cancer Discov. 2016;6:714-26 pubmed publisher

product information

Catalog Number :

82184

Product Name :

pDONR223_STAT3_p.A662C_N664C

article :

doi	10.1158/2159-8290.CD-16-0160
id	22007
pubmed_id	27147599

bacterial resistance :

Spectinomycin

cloning :

backbone

pDONR223

backbone_mutation

backbone_origin

Invitrogen

backbone_size

2790

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Other

Gateway Entry vector

growth notes :

Closed state: stop codon immediately follows insert Supporting reference: Systematic morphological profiling of human gene and allele function via Cell Painting. Rohban MH, et al. Elife. 2017, Mar 18;6. pii: e24060. PubMed PMID 28315521

growth strain :

Gateway Donor vector containing STAT3 , part of the Target Accelerator Plasmid Collection.

origin :

pi :

alt_names

cloning

clone_method	Gateway Cloning
cloning_site_3
cloning_site_5
promoter	None
sequencing_primer_3	M13-Rev
sequencing_primer_5	M13pUC-fwd
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	ADMIO, ADMIO1, APRF, HIES
gene	STAT3
id	6774

genbank_ids

NM_139276.2

mutation

A662C, N664C

name

STAT3

shRNA_sequence

size

species

9606

Homo sapiens