pDONR223_ERBB3_WT | Addgene 82114 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pDONR223_ERBB3_WT

catalog :

82114

citations: 4

Reference
Matsuda K, Hirayama D, Hino N, Kuno S, Sakaue Sawano A, Miyawaki A, et al. Knockout of all ErbB-family genes delineates their roles in proliferation, survival, and migration. J Cell Sci. 2023;: pubmed publisher
Hanker A, Brown B, Meiler J, Marin A, Jayanthan H, Ye D, et al. Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity. Cancer Cell. 2021;39:1099-1114.e8 pubmed publisher
Shin D, Jo J, Han J. Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1-Mediated Lung Cancer. Mol Cancer Ther. 2018;17:2024-2033 pubmed publisher
Kim E, Ilic N, Shrestha Y, Zou L, Kamburov A, Zhu C, et al. Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles. Cancer Discov. 2016;6:714-26 pubmed publisher

product information

Catalog Number :

82114

Product Name :

pDONR223_ERBB3_WT

article :

doi	10.1158/2159-8290.CD-16-0160
id	22007
pubmed_id	27147599

bacterial resistance :

Spectinomycin

cloning :

backbone

pDONR223

backbone_mutation

backbone_origin

Invitrogen

backbone_size

2790

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Other

Gateway Entry vector

growth notes :

Open state: NO stop codon immediately follows insert. Supporting reference: Systematic morphological profiling of human gene and allele function via Cell Painting. Rohban MH, et al. Elife. 2017, Mar 18;6. pii: e24060. PubMed PMID 28315521

growth strain :

Gateway Donor vector containing ERBB3 , part of the Target Accelerator Plasmid Collection.

origin :

pi :

alt_names

NM_001982.3

cloning

clone_method	Gateway Cloning
cloning_site_3
cloning_site_5
promoter	None
sequencing_primer_3	M13-Rev
sequencing_primer_5	M13pUC-fwd
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	ErbB-3, FERLK, HER3, LCCS2, MDA-BF-1, VSCN1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
gene	ERBB3
id	2065

genbank_ids

mutation

name

ERBB3

shRNA_sequence

size

species

9606

Homo sapiens