This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-ALK5 T204D
catalog :
80877
citations: 2
Reference
Zhu X, Wang Y, Soaita I, Lee H, Bae H, Boutagy N, et al. Acetate controls endothelial-to-mesenchymal transition. Cell Metab. 2023;35:1163-1178.e10 pubmed publisher
Morén A, Imamura T, Miyazono K, Heldin C, Moustakas A. Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases. J Biol Chem. 2005;280:22115-23 pubmed
product information
Catalog Number :
80877
Product Name :
pcDNA3-ALK5 T204D
article :
doi10.1074/jbc.M414027200
id21909
pubmed_id15817471
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
mammalian expression of constitutively active ALK5 T204D
origin :
37
pi :
alt_names
TGFBR1
transforming growth factor beta receptor 1
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TBR-i, TBRI, TGFR-1, tbetaR-I
geneTGFBR1
id7046
genbank_ids
mutationT204D (constitutively active)
nameALK5
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagHA
resistance markers :
2976
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA