pcDNA3-ALK3 wt | Addgene 80873 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pcDNA3-ALK3 wt

catalog :

80873

citations: 6

Reference
Meng Z, Zhang S, Li W, Wang Y, Wang M, Liu X, et al. Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis. Eur Heart J. 2023;44:2763-2783 pubmed publisher
Xie C, Jiang W, Lacroix J, Luo Y, Hao J. Insight into Molecular Mechanism for Activin A-Induced Bone Morphogenetic Protein Signaling. Int J Mol Sci. 2020;21: pubmed publisher
Renault L, Pati xf1 o L, Magnin F, Delemer B, Young J, Laissue P, et al. BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency. J Clin Endocrinol Metab. 2020;105: pubmed publisher
Peiffer B, Qi L, Ahmadi A, Wang Y, Guo Z, Peng H, et al. Activation of BMP Signaling by FKBP12 Ligands Synergizes with Inhibition of CXCR4 to Accelerate Wound Healing. Cell Chem Biol. 2019;26:652-661.e4 pubmed publisher
Botello Smith W, Alsamarah A, Chatterjee P, Xie C, Lacroix J, Hao J, et al. Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock. PLoS Comput Biol. 2017;13:e1005711 pubmed publisher
Raja E, Tzavlaki K, Vuilleumier R, Edlund K, Kahata K, Zieba A, et al. The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling. Oncotarget. 2016;7:1120-43 pubmed publisher

product information

Catalog Number :

80873

Product Name :

pcDNA3-ALK3 wt

article :

doi	10.18632/oncotarget.6683
id	21908
pubmed_id	26701726

bacterial resistance :

Ampicillin

cloning :

backbone

pcDNA3

backbone_mutation

backbone_origin

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

This plasmid contains a P2A mutation compared to NM_004329.2 and SL insertion after the c-terminal HA tag. The depositor states that these discrepancies do not affect plasmid function.

growth strain :

mammalian expression of ALK3 WT

origin :

pi :

alt_names

BMPR1A

bone morphogenetic protein receptor type 1A

cloning

clone_method	Restriction Enzyme
cloning_site_3	XhoI
cloning_site_5	EcoRI
promoter	CMV
sequencing_primer_3	BGH-rev
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	10q23del, ACVRLK3, ALK-3, ALK3, BMPR-1A, CD292, SKR5
gene	BMPR1A
id	657

genbank_ids

mutation

name

ALK3

shRNA_sequence

size

species

9606

Homo sapiens